Wear Experience With Daily Disposable Contact Lenses for Astigmatism Over a Long-Wear Day

NCT07303920 | Recruiting FDA Device

• 1 other identifier: 20252462
• Study Type: interventional
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study to assess the wear experience of people who have astigmatism when wearing a daily disposable contact lens for astigmatism over long days of wear.

Conditions

Astigmatism

Outcome Measures

Primary Outcomes (1)

• Comfort

  Proportion of participants with positive Visual Analog Scale (VAS, \>50 on a 0-100 scale)

  Measured over 16 hours of wear

Study Arms (1)

Contact Lens Wear

OTHER

All participants will be fit with the study contact lenses for astigmatism

Device: Daily disposable contact lenses for astigmatism

Interventions

Daily disposable contact lenses for astigmatism DEVICE

All participants will be fit with the study lenses

Also known as: Dailies Total1 for Astigmatism

Contact Lens Wear

Eligibility Criteria

• Age: 18 Years - 40 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Current soft toric contact lens wearer with long hours of wear
• Willing to follow the contact lens wearing schedule required by the study
• Vision 20/25 or better with current soft toric contact lenses
• Self-report completion of a comprehensive eye examination in the past two years

You may not qualify if:

• Have a history of corneal ocular surgery
• Have current ocular inflammation or infection as assessed by the study investigator who will complete the study
• Are past rigid contact lens wearers
• Have a history of being diagnosed with dry eye or ocular allergies
• Have known systemic health conditions that are thought to alter tear film physiology
• Have a history of viral eye disease
• Have a history of ocular surgery
• Have a history of severe ocular trauma
• Have a history of corneal dystrophies or degenerations
• Have active ocular infection or inflammation
• Are currently using isotretinoin-derivatives or ocular medications
• Are pregnant or breast feeding

Sponsors & Collaborators

• Ohio State University: lead
• Alcon Research: collaborator

Study Sites (1)

The Ohio State University College of Optometry

Columbus, Ohio, 43210, United States

RECRUITING

MeSH Terms

Conditions

Astigmatism

Condition Hierarchy (Ancestors)

Refractive Errors; Eye Diseases

Central Study Contacts

Study Coordinators

CONTACT

614-292-8858; OPT-EyeStudies@osu.edu

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: OTHER
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: December 23, 2025
• First Posted: December 26, 2025
• Study Start: March 4, 2026
• Primary Completion (Estimated): June 30, 2026
• Study Completion (Estimated): June 30, 2026
• Last Updated: March 25, 2026

Record last verified: 2026-03

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)