NCT06098937

Brief Summary

Approximately thirty contact lens adapted subjects will be enrolled in this feasibility, bilateral, randomized, double masked (subject and investigator masked), repeated measures insertion study.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
30

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Sep 2023

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 5, 2023

Completed
22 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 27, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 27, 2023

Completed
2 days until next milestone

First Submitted

Initial submission to the registry

September 29, 2023

Completed
26 days until next milestone

First Posted

Study publicly available on registry

October 25, 2023

Completed
1.1 years until next milestone

Results Posted

Study results publicly available

December 10, 2024

Completed
Last Updated

December 10, 2024

Status Verified

December 1, 2024

Enrollment Period

22 days

First QC Date

September 29, 2023

Results QC Date

October 1, 2024

Last Update Submit

December 5, 2024

Conditions

Keywords

Contact Lens

Outcome Measures

Primary Outcomes (1)

  • Primary Gaze Orientation for 5 Minutes

    Primary gaze orientation is measured in degrees using a slit lamp and reticule.

    5 minutes after lens insertion

Study Arms (4)

Kalifilcon A Daily Disposable Toric

EXPERIMENTAL

Kalifilcon A Daily Disposable Toric

Device: Kalifilcon Toric Lens

Total1 for Astigmatism

ACTIVE COMPARATOR

Total1 for Astigmatism

Device: Total1 for Astigmatism

Precision1 for Astigmatism

ACTIVE COMPARATOR

Precision1 for Astigmatism

Device: Precision1 for Astigmatism

MyDay Toric

ACTIVE COMPARATOR

MyDay Toric

Device: MyDay Toric

Interventions

Kalifilcon A Daily Disposable Toric for Ametropia

Kalifilcon A Daily Disposable Toric

Total1 for Astigmatism

Total1 for Astigmatism

Precision1 for Astigmatism

Precision1 for Astigmatism

MyDay Toric

MyDay Toric

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Be 18 years or older on the date the Informed Consent Form (ICF) is signed and have capacity to read, understand and provide written voluntary informed consent.
  • Have physiologically normal anterior segments not exhibiting clinically significant biomicroscopy findings.
  • Have no active ocular disease or allergic conjunctivitis.
  • Not be using any topical ocular medications.
  • Be willing and able to follow instructions.
  • Have signed a statement of informed consent.

You may not qualify if:

  • Participating in a conflicting study in the opinion of the Investigator.
  • Considered by the Investigator to not be a suitable candidate for participation

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Bausch & Lomb, Incorporated

Rochester, New York, 14609, United States

Location

MeSH Terms

Conditions

Astigmatism

Condition Hierarchy (Ancestors)

Refractive ErrorsEye Diseases

Results Point of Contact

Title
Jeffery Schafer, OD, MS Director, Clinical Research
Organization
Bausch & Lomb

Publication Agreements

PI is Sponsor Employee
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, INVESTIGATOR
Purpose
TREATMENT
Intervention Model
CROSSOVER
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 29, 2023

First Posted

October 25, 2023

Study Start

September 5, 2023

Primary Completion

September 27, 2023

Study Completion

September 27, 2023

Last Updated

December 10, 2024

Results First Posted

December 10, 2024

Record last verified: 2024-12

Data Sharing

IPD Sharing
Will not share

Locations