NCT06069609

Brief Summary

Brief summary: Approximately 30 soft toric contact lens adapted subjects will be enrolled in this feasibility, bilateral, randomized, double-masked (subject and investigator), repeated measures insertion study.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
30

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Aug 2023

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 11, 2023

Completed
4 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 15, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 15, 2023

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

September 19, 2023

Completed
17 days until next milestone

First Posted

Study publicly available on registry

October 6, 2023

Completed
1.7 years until next milestone

Results Posted

Study results publicly available

July 1, 2025

Completed
Last Updated

July 1, 2025

Status Verified

June 1, 2025

Enrollment Period

4 days

First QC Date

September 19, 2023

Results QC Date

September 24, 2024

Last Update Submit

June 12, 2025

Conditions

Keywords

Contact Lens

Outcome Measures

Primary Outcomes (1)

  • Primary Gaze Orientation

    Primary gaze orientation 5 minutes after lens insertion

    Assessed 5 minutes after lens insertion

Study Arms (2)

kalifilcon A Daily Disposable Toric

EXPERIMENTAL
Device: kalifilcon A Daily Disposable Toric

Acuvue Oasys 1-Day for Astigmatism

ACTIVE COMPARATOR
Device: Acuvue Oasys 1-Day for Astigmatism

Interventions

kalifilcon A Daily Disposable Toric

kalifilcon A Daily Disposable Toric

Acuvue Oasys 1-Day for Astigmatism

Acuvue Oasys 1-Day for Astigmatism

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Be 18 years or older on the date the Informed Consent Form (ICF) is signed and have capacity to read, understand and provide written voluntary informed consent.
  • Have physiologically normal anterior segments not exhibiting clinically significant biomicroscopy findings.
  • Have no active ocular disease or allergic conjunctivitis
  • Not be using any topical ocular medications.
  • Be willing and able to follow instructions.
  • Have signed a statement of informed consent.

You may not qualify if:

  • The subject is not eligible to participate in the study if the subject is:
  • Participating in a conflicting study in the opinion of the Investigator.
  • Considered by the Investigator to not be a suitable candidate for participation.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Bausch & Lomb, Incorporated

Rochester, New York, 14609, United States

Location

MeSH Terms

Conditions

Astigmatism

Condition Hierarchy (Ancestors)

Refractive ErrorsEye Diseases

Results Point of Contact

Title
Jeffery Schafer, OD, MS Director, Clinical Research
Organization
Bausch & Lomb

Publication Agreements

PI is Sponsor Employee
Yes
Restrictive Agreement
No

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, INVESTIGATOR
Purpose
TREATMENT
Intervention Model
CROSSOVER
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 19, 2023

First Posted

October 6, 2023

Study Start

August 11, 2023

Primary Completion

August 15, 2023

Study Completion

August 15, 2023

Last Updated

July 1, 2025

Results First Posted

July 1, 2025

Record last verified: 2025-06

Data Sharing

IPD Sharing
Will not share

Locations