The Effect of a Single Training Session on Changes in Inflammatory, Hormonal, and Metabolic Markers in Athletes.

NCT07264751 | Completed

• 1 other identifier: AKS wrestlers
• Study Type: observational
• Target: 5
• Locations: 1 country
• Sites: 1

Brief Summary

The study aims to assess the acute response of wrestlers to a single training session. Short-term changes in inflammatory, hormonal, and metabolic markers will be analyzed, which may reflect the development of fatigue and recovery processes following intense exercise. Participation in the study involves performing a standard training session and collecting blood samples at three time points to assess the physiological response. The results will provide a better understanding of the mechanisms of adaptation to exercise in strength and endurance athletes.

Conditions

Training; Hormone; Exercise Training; Inflammation Biomarkers

Keywords

wrestlers; catecholamines; Single training session; Inflammatory markers; Hormonal response

Outcome Measures

Primary Outcomes (6)

• hsCRP

  highly sensitive reactive C-protein

  1. Before training (at rest), 2. Immediately after training, 3. 24 hours after exercise.

• CK

  creatine kinase

  1. Before training (at rest), 2. Immediately after training, 3. 24 hours after exercise.

• TNF-alpha

  tumor necrosis factor alpha

  1. Before training (at rest), 2. Immediately after training, 3. 24 hours after exercise.

• IL-6

  Interleukine-6

  1. Before training (at rest), 2. Immediately after training, 3. 24 hours after exercise.

• A

  Adrenaline

  1. Before training (at rest), 2. Immediately after training, 3. 24 hours after exercise.

• Noradrenaline

  Noradrenaline

  1. Before training (at rest), 2. Immediately after training, 3. 24 hours after exercise.

Secondary Outcomes (4)

• Kortisol

  1. Before training (at rest), 2. Immediately after training, 3. 24 hours after exercise.

• TP

  1. Before training (at rest), 2. Immediately after training, 3. 24 hours after exercise.

• Urea

  1. Before training (at rest), 2. Immediately after training, 3. 24 hours after exercise.

• Albumin

  1. Before training (at rest), 2. Immediately after training, 3. 24 hours after exercise.

Other Outcomes (1)

• UA

  1. Before training (at rest), 2. Immediately after training, 3. 24 hours after exercise.

Interventions

physical training BEHAVIORAL

The intervention consists of a standardized, high-intensity wrestling training session designed to simulate typical strength-endurance exercise performed by elite wrestlers. The session includes sport-specific drills, resistance exercises, and aerobic conditioning components appropriate for this athletic discipline. All participants will perform the session under supervision to ensure safety and adherence to the planned intensity and duration.

Eligibility Criteria

• Sex: male
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The study participants are elite wrestlers who are also members of a national-level sports club and members of the national team. All athletes have experience competing in international events. The group includes athletes who have won medals at both national and international competitions. Participants are highly trained, with extensive experience in strength-endurance wrestling disciplines, and represent the top competitive level in their sport. The study aims to evaluate acute physiological responses to a single high-intensity training session in this highly specialized discipline.

You may qualify if:

• Currently engaged in regular strength-endurance wrestling training.
• Medically cleared for high-intensity exercise by a sports physician.
• Willingness to participate and provide written informed consent.
• Availability to attend the training session and all blood sampling time points (pre-training, immediately post-training, 24 hours post-training)

You may not qualify if:

• Presence of acute or chronic illness that may affect exercise performance or physiological response
• Recent musculoskeletal injury limiting participation in high-intensity training.
• Use of medications or supplements that may interfere with hormonal, inflammatory, or metabolic markers
• History of endocrine disorders, adrenal insufficiency, or other conditions affecting catecholamine or cortisol levels
• Inability or unwillingness to comply with study procedures.

Sponsors & Collaborators

• Poznan University of Physical Education: lead

Study Sites (1)

Poznań University of Physical Education, Faculty of Physical Culture in Gorzów Wielkopolski

Gorzów Wielkopolski, Polska, 66-400, Poland

Location

MeSH Terms

Interventions

Physical Conditioning, Human

Intervention Hierarchy (Ancestors)

Exercise; Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Officials

• Anna Kasperska, PhD

  Poznań University of Physical Education, Faculty of Sport Sciences in Gorzów Wielkopolski, Poland;

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: November 23, 2025
• First Posted: December 4, 2025
• Study Start: February 1, 2014
• Primary Completion: May 1, 2014
• Study Completion: June 1, 2014
• Last Updated: December 4, 2025

Record last verified: 2025-10

Data Sharing

• IPD Sharing: Will not share

Locations

PL (1)