NCT07200960

Brief Summary

The study aims to compare the efficacy in pain control and total opioid consumption after the use of ESPB and retrolaminar block in patients undergoing major oncological breast surgery..

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
90

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Feb 2022

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2022

Completed
2.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2024

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2024

Completed
12 months until next milestone

First Submitted

Initial submission to the registry

September 29, 2025

Completed
2 days until next milestone

First Posted

Study publicly available on registry

October 1, 2025

Completed
Last Updated

January 8, 2026

Status Verified

January 1, 2026

Enrollment Period

2.6 years

First QC Date

September 29, 2025

Last Update Submit

January 6, 2026

Conditions

Pain ManagementOpoid Managment

Outcome Measures

Primary Outcomes (1)

  • Comparison of pain score of patients receiving ESPB and retrolaminar block

    Numeric rating scale score

    2hours post surgery

Secondary Outcomes (1)

  • Comparison of total opioid consumption in 24 hours of patients receiving ESPB and retrolaminar block

    24 hours post surgery

Study Arms (2)

Patient receiving ESPB for major oncological breast surgery

EXPERIMENTAL

Patient receiving ESPB for major oncological breast surgery

Procedure: ESPB

Patient receiving Retrolaminar block for major oncological breast surgery

EXPERIMENTAL

Patient receiving ESPB for major oncological breast surgery

Procedure: ESPB

Interventions

ESPBPROCEDURE

Patient receiving ESPB for major oncological breast surgery Patient receiving Retrolaminar Block for major oncological breast surgery

Also known as: Retrolaminar Block
Patient receiving ESPB for major oncological breast surgeryPatient receiving Retrolaminar block for major oncological breast surgery

Eligibility Criteria

Age18 Years - 60 Years
Sexfemale(Gender-based eligibility)
Gender Eligibility Detailsfemale population has a bigger incision as compared to male population.
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Female patients between 18- 60 years ASA 1 and 2

You may not qualify if:

  • Patient refusal Allergic reaction infection emergency case BMI \>35

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Shaukat Khanum Memorial Cancer Hospital & Research Centre.

Lahore, Punjab Province, Pakistan

Location

MeSH Terms

Conditions

Agnosia

Condition Hierarchy (Ancestors)

Perceptual DisordersNeurobehavioral ManifestationsNeurologic ManifestationsNervous System DiseasesSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Masking Details
will be asked regarding the group of blocks being employed.
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 29, 2025

First Posted

October 1, 2025

Study Start

February 1, 2022

Primary Completion

September 1, 2024

Study Completion

October 1, 2024

Last Updated

January 8, 2026

Record last verified: 2026-01

Data Sharing

IPD Sharing
Will not share

Locations

PA(1)