NCT07129044

Brief Summary

The aim of this randomized controlled trial was to evaluate the effect of the flipped classroom model on pediatric pain management knowledge and learning motivation among nursing students. A total of 84 third-year nursing students from a public university in Turkey were randomly assigned to intervention (n=42) and control (n=42) groups. The intervention group received education using the flipped classroom model, while the control group followed a self-directed learning approach. Data were collected at three time points: before the intervention (pre-test), one month after the intervention (post-test), and three months after the intervention (follow-up test). The Pediatric Pain Knowledge Test and the Motivation Scale Towards Learning were used to assess outcomes. At baseline, there were no significant differences between the groups. Post-test and follow-up results showed that the intervention group demonstrated a statistically significant and sustained increase in both pediatric pain knowledge and learning motivation scores (p\<0.001), while the control group showed no meaningful change. These findings support the flipped classroom model as an effective and sustainable teaching strategy in nursing education, particularly for improving knowledge and motivation in pediatric pain management.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
84

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Feb 2022

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2022

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 20, 2022

Completed
26 days until next milestone

Study Completion

Last participant's last visit for all outcomes

August 15, 2022

Completed
3 years until next milestone

First Submitted

Initial submission to the registry

August 4, 2025

Completed
15 days until next milestone

First Posted

Study publicly available on registry

August 19, 2025

Completed
Last Updated

August 19, 2025

Status Verified

August 1, 2025

Enrollment Period

6 months

First QC Date

August 4, 2025

Last Update Submit

August 11, 2025

Conditions

Keywords

Pediatric pain managementFlipped classroomNursing studentsLearning motivationRandomized controlled trial

Outcome Measures

Primary Outcomes (1)

  • Pediatric Pain Management Knowledge Score

    The Pediatric Pain Management Knowledge Scale, developed by Aydın \& Bektaş (2021), measures nursing students' knowledge of pediatric pain. It consists of 29 items rated on a 5-point Likert scale, covering six sub-dimensions: pain awareness (6 items), pain physiopathology (4), barriers to pain management (11), pain diagnosis (2), pain assessment (2), and pain control (4). Items 3, 6, 8, 10-15, 17, and 21 are reverse coded. Scores range from 29 to 145; higher scores indicate greater knowledge. In this study, Cronbach's alpha was 0.845.

    Baseline (pre-test), 1 month after intervention (post-test), and 3 months after intervention (follow-up)

Secondary Outcomes (1)

  • Motivation Level Toward Instructional Materials

    Baseline (pre-test), 1 month after intervention (post-test), and 3 months after intervention (follow-up)

Study Arms (2)

Flipped Classroom Training on Pediatric Pain Management

EXPERIMENTAL

Participants in this group received pediatric pain management training through a flipped classroom model for 4 weeks. Training videos and readings were provided in advance and in-class sessions included interactive activities, discussions, and case-based learning.

Behavioral: Flipped Classroom Training on Pediatric Pain Management

Self-Directed Learning on Pediatric Pain Management

ACTIVE COMPARATOR

Participants in this group received the same pediatric pain management materials as the intervention group (lecture notes, readings, and video lectures) for self-study without any interactive activities or instructor-led sessions.

Behavioral: Self-Directed Learning on Pediatric Pain Management

Interventions

Participants in this group received pediatric pain management training designed to increase nursing students' knowledge and motivation. The training was delivered using a flipped classroom model over 4 weeks. Students were provided with pre-class educational materials, including video lectures, readings, and lecture notes. In-class sessions included interactive activities, discussions, case-based learning, and problem-solving exercises. Content was based on current pediatric pain management guidelines and adapted to nursing education standards.

Flipped Classroom Training on Pediatric Pain Management

Participants in this group received pediatric pain management training designed to increase nursing students' knowledge and motivation. Students were provided with the same pre-class educational materials as the intervention group, including video lectures, readings, and lecture notes, for self-study without any interactive activities or instructor-led sessions. Content was based on current pediatric pain management guidelines and adapted to nursing education standards.

Self-Directed Learning on Pediatric Pain Management

Eligibility Criteria

Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Being enrolled in the "Child Health and Diseases Nursing" course for the first time
  • Having access to the Internet and a computer or smartphone
  • Agreeing to attend synchronous sessions via Google Classroom
  • Volunteering to participate in the study

You may not qualify if:

  • Having previously received any education on pediatric pain management
  • Withdrawing consent at any point during the study
  • Failing to complete the pre-test, post-test, or three-month follow-up assessment (e.g., missing a measurement session due to internet connectivity issues)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Mehmet Akif Ersoy University, Faculty of Health Sciences

Burdur, 15100, Turkey (Türkiye)

Location

Related Publications (33)

  • Ekim A, Ocakci AF. Knowledge and attitudes regarding pain management of pediatric nurses in Turkey. Pain Manag Nurs. 2013 Dec;14(4):e262-e267. doi: 10.1016/j.pmn.2012.02.004. Epub 2012 Apr 4.

  • Martin F, Sun T, Westine CD. A systematic review of research on online teaching and learning from 2009 to 2018. Comput Educ. 2020 Dec;159:104009. doi: 10.1016/j.compedu.2020.104009. Epub 2020 Sep 9.

  • Paralikar S, Shah CJ, Joshi A, Kathrotia R. Acquisition of Higher-Order Cognitive Skills (HOCS) Using the Flipped Classroom Model: A Quasi-Experimental Study. Cureus. 2022 Apr 18;14(4):e24249. doi: 10.7759/cureus.24249. eCollection 2022 Apr.

  • Zhang D, Huang A, Lei Y, Liu H, Yang L, Wang C, Yuan T, Li X, Zhang L, Shang W. Nursing students' experiences and perceptions regarding in-class flipped classroom: a mixed-methods study. BMC Med Educ. 2025 May 8;25(1):675. doi: 10.1186/s12909-025-07248-x.

  • Yuan L. Effect of Educational Interventions for Improving the Nurses' Knowledge, Attitude, and Practice of Pediatric Pain Management: A Aystematic Review and Meta-Analysis. Pain Manag Nurs. 2024 Aug;25(4):e271-e278. doi: 10.1016/j.pmn.2024.04.005. Epub 2024 May 3.

  • Xu P, Chen Y, Nie W, Wang Y, Song T, Li H, Li J, Yi J, Zhao L. The effectiveness of a flipped classroom on the development of Chinese nursing students' skill competence: A systematic review and meta-analysis. Nurse Educ Today. 2019 Sep;80:67-77. doi: 10.1016/j.nedt.2019.06.005. Epub 2019 Jun 14.

  • Guidelines on the management of chronic pain in children. Geneva: World Health Organization; 2020. Available from http://www.ncbi.nlm.nih.gov/books/NBK566553/

  • Ulgen H, Tufekci FG. The Effect of Pain Management Education on Nurses' Pain Knowledge and Attitudes. Pain Manag Nurs. 2024 Jun;25(3):e186-e191. doi: 10.1016/j.pmn.2023.12.011. Epub 2024 Feb 10.

  • Ung A, Salamonson Y, Hu W, Gallego G. Assessing knowledge, perceptions and attitudes to pain management among medical and nursing students: a review of the literature. Br J Pain. 2016 Feb;10(1):8-21. doi: 10.1177/2049463715583142. Epub 2015 May 13.

  • Shi, X.-Y., Yin, Q., Wang, Q.-W., Lu, B.-R., Li, G.-X., Huang, S.-H., & Sun, Z.-G. (2025). Is the flipped classroom more effective than the traditional classroom in clinical medical education: A systematic review and meta-analysis. Frontiers in Education, 9, Article 1485540. https://doi.org/10.3389/feduc.2024.1485540

    RESULT
  • Shanmugam SR, Alabdullah AAS, Alenezi MH, Aldughyshim SK, Alnemer MF, Almutairi WK, Alhadyan GS, Albugomi RZ, Alkhulayfi FA. Knowledge and attitudes toward pediatric pain management among nursing interns from a selected university in Riyadh, Saudi Arabia: a descriptive cross-sectional quantitative study. PeerJ. 2025 Apr 21;13:e19288. doi: 10.7717/peerj.19288. eCollection 2025.

  • Atefeh S. Barriers and facilitators of pain management in children: a scoping review. BMC Anesthesiol. 2025 Apr 1;25(1):148. doi: 10.1186/s12871-025-02941-2.

  • Shah P, Siu A. Considerations for neonatal and pediatric pain management. Am J Health Syst Pharm. 2019 Sep 16;76(19):1511-1520. doi: 10.1093/ajhp/zxz166.

  • Raja SN, Carr DB, Cohen M, Finnerup NB, Flor H, Gibson S, Keefe FJ, Mogil JS, Ringkamp M, Sluka KA, Song XJ, Stevens B, Sullivan MD, Tutelman PR, Ushida T, Vader K. The revised International Association for the Study of Pain definition of pain: concepts, challenges, and compromises. Pain. 2020 Sep 1;161(9):1976-1982. doi: 10.1097/j.pain.0000000000001939.

  • Merrou S, Baslam A, Idrissi Jouicha A, Ouhaz Z, El Adib AR. Blended learning and simulation in nursing education: A quasi-experimental study on a nursing institute. J Educ Health Promot. 2023 Sep 29;12:303. doi: 10.4103/jehp.jehp_72_23. eCollection 2023.

  • Liu, Y., Li, Y., Lei, M., Liu, P., Theobald, J., Meng, L., Liu, T., Zhang, C., & Jin, C. (2018). Effectiveness of the flipped classroom on the development of self-directed learning in nursing education: A meta-analysis. Frontiers of Nursing, 5, 317-329. https://doi.org/10.1515/fon-2018-0032

    RESULT
  • Liu YM, Lin GL, Chao KY, Jih HJ, Yang BH, Chiang YC. Comparison of the effectiveness of teaching strategies for a pediatric pain management program for undergraduate nursing students: A quantitative evaluation using an objective structured clinical examination. Nurse Educ Pract. 2020 Feb;43:102707. doi: 10.1016/j.nepr.2020.102707. Epub 2020 Jan 18.

  • Kutu, H., & Sözbilir, M. (2011). Öğretim Materyalleri Motivasyon Anketinin Türkçeye Uyarlanması: Güvenirlik ve Geçerlik Çalışması. Necatibey Faculty of Education Electronic Journal of Science and Mathematics Education, 5(1), 292-312.

    RESULT
  • Keller, J. M. (2006). Development of two measures of learner motivation. In Academy of Human Resource Development International Conference Proceedings (pp. 1063-1070).

    RESULT
  • International Association for the Study of Pain. (2018). IASP curriculum outline on pain for nursing. https://www.iasp-pain.org/education/curricula/iasp-curriculum-outline-on-pain-for-nursing/

    RESULT
  • Gadallah, M. A., Hassan, A. M., Shargawy, S. A. (2017). Undergraduate nursing students' knowledge and attitude regarding pain management of children in Upper Egypt. J Nurs Educ Pract, 7(6), 100-7. https://doi.org/10.5430/jnep.v7n6p100

    RESULT
  • ChildKind International. (2020). Homepage. https://childkindinternational.org/

    RESULT
  • Chen, Y., Wang, Y., Kinshuk, & Chen, N. S. (2014). Is FLIP enough? Or should we use the FLIPPED model instead? Computers & Education, 79, 16-27. https://doi.org/10.1016/j.compedu.2014.07.004

    RESULT
  • Busebaia TJA, Thompson J, Fairbrother H, Ali P. The role of family in supporting adherence to diabetes self-care management practices: An umbrella review. J Adv Nurs. 2023 Oct;79(10):3652-3677. doi: 10.1111/jan.15689. Epub 2023 May 7.

  • Bond M. Pain education issues in developing countries and responses to them by the International Association for the Study of Pain. Pain Res Manag. 2011 Nov-Dec;16(6):404-6. doi: 10.1155/2011/654746.

  • Betihavas V, Bridgman H, Kornhaber R, Cross M. The evidence for 'flipping out': A systematic review of the flipped classroom in nursing education. Nurse Educ Today. 2016 Mar;38:15-21. doi: 10.1016/j.nedt.2015.12.010. Epub 2015 Dec 22.

  • Aydin B, Bektas M. Pediatric Pain Management Knowledge Levels of Intern Nursing Students. Pain Manag Nurs. 2020 Jun;21(3):290-298. doi: 10.1016/j.pmn.2019.06.012. Epub 2019 Aug 8.

  • WHO Guidelines on the Pharmacological Treatment of Persisting Pain in Children with Medical Illnesses. Geneva: World Health Organization; 2012. Available from http://www.ncbi.nlm.nih.gov/books/NBK138354/

  • Faul F, Erdfelder E, Lang AG, Buchner A. G*Power 3: a flexible statistical power analysis program for the social, behavioral, and biomedical sciences. Behav Res Methods. 2007 May;39(2):175-91. doi: 10.3758/bf03193146.

  • 12. Cohen, J. (2013). Statistical power analysis for the behavioral sciences. Routledge. https://doi.org/10.4324/9780203771587

    RESULT
  • Barranquero-Herbosa M, Abajas-Bustillo R, Ortego-Mate C. Effectiveness of flipped classroom in nursing education: A systematic review of systematic and integrative reviews. Int J Nurs Stud. 2022 Nov;135:104327. doi: 10.1016/j.ijnurstu.2022.104327. Epub 2022 Jul 21.

  • Alshehri FA, Levett-Jones T, Pich J. Nursing students' knowledge of and attitudes towards pain management: An integrative review. Nurse Educ Today. 2024 Aug;139:106207. doi: 10.1016/j.nedt.2024.106207. Epub 2024 Apr 10.

  • 1. Akdeniz Kudubeş, A., Bektaş, İ., & Bektaş, M. (2021). Nursing role in children pain management. Journal of Education and Research in Nursing, 18(1), 107-113. https://doi.org/10.5152/jern.2021.91489

    RESULT

MeSH Terms

Conditions

Agnosia

Condition Hierarchy (Ancestors)

Perceptual DisordersNeurobehavioral ManifestationsNeurologic ManifestationsNervous System DiseasesSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Masking Details
Not applicable. Participants and researchers were aware of group assignments due to the nature of the educational intervention.
Purpose
OTHER
Intervention Model
PARALLEL
Model Details: Participants were randomly assigned to either the intervention group receiving flipped classroom-based pediatric pain management training or the control group receiving self-directed learning. The intervention lasted four weeks, and data were collected at three time points: pre-test (baseline), post-test (immediately after the intervention), and follow-up (three months later).
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Assistant Professor, Department of Pediatric Nursing, Faculty of Health Sciences, Burdur Mehmet Akif Ersoy University

Study Record Dates

First Submitted

August 4, 2025

First Posted

August 19, 2025

Study Start

February 1, 2022

Primary Completion

July 20, 2022

Study Completion

August 15, 2022

Last Updated

August 19, 2025

Record last verified: 2025-08

Data Sharing

IPD Sharing
Will not share

Individual participant data will not be shared because participants did not provide consent for external data sharing and the study materials are governed by institutional privacy regulations. Data will remain accessible only to the study team

Locations