Alternative to Gait Speed in Sarcopenia Assessment

NCT07065448 | Completed

• 1 other identifier: IstPRMTRH-TYY1
• Study Type: observational
• Target: 96
• Locations: 1 country
• Sites: 1

Brief Summary

This study aims to assess the reliability of the Elbow Performance Test as an upper extremity-based alternative for evaluating sarcopenia severity. Unlike traditional lower extremity-focused assessments, this test may offer a practical solution for individuals with mobility limitations or comorbidities affecting the lower limbs. Participants will include older adults with sarcopenia and healthy young adults. Functional tests, including the 4-meter Gait Speed Test, SPPB, TUG, and the Elbow Performance Test, will be administered twice within a 7-10-day interval. Reliability will be analyzed using intraclass correlation coefficients (ICC).

Conditions

Sarcopenia; Elderly

Keywords

sarcopenia; reliability and validity; muscle strength; upper extremity function; physical performance parameters

Outcome Measures

Primary Outcomes (1)

• the Elbow Performance Test

  The total time required to complete thirty consecutive elbow flexion-extension movements, performed with a one-kilogram sandbag attached to the distal forearm of the dominant arm.

  Two assessment sessions conducted seven to ten days apart to evaluate test-retest reliability using intraclass correlation coefficients (ICC).

Secondary Outcomes (3)

• the 4-meter Gait Speed Test

  Two assessment sessions conducted seven to ten days apart to evaluate test-retest reliability using intraclass correlation coefficients (ICC).

• the Short Physical Performance Battery (SPPB)

  Two assessment sessions conducted seven to ten days apart to evaluate test-retest reliability using intraclass correlation coefficients (ICC).

• Timed Up and Go (TUG)

  Two assessment sessions conducted seven to ten days apart to evaluate test-retest reliability using intraclass correlation coefficients (ICC).

Study Arms (2)

Group 1

older adults with sarcopenia

Other: physical performance tests

Group 2

healthy young adults

Other: physical performance tests

Interventions

physical performance tests OTHER

All participants underwent the 4-meter Gait Speed Test, the Short Physical Performance Battery (SPPB), the Timed Up and Go (TUG) test, and the Elbow Performance Test twice, with a 7-10-day interval between sessions. In the Elbow Performance Test, a 1-kilogram sandbag was fixed to the distal forearm of the dominant arm, and participants were asked to perform 30 consecutive elbow flexion-extension movements.

Group 1; Group 2

Eligibility Criteria

• Age: 18 Years+
• Sex: male
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Sarcopenia Group and Healthy Young Control Group

You may qualify if:

• Individuals who consent to participate in the study
• \*Sarcopenia Group
• Male participants aged 60 years or older
• Diagnosed with sarcopenia according to EWGSOP2 criteria
• \*Healthy Young Control Group
• Male participants aged 40 years or younger
• SARC-F screening test score \< 4

You may not qualify if:

• Inability to cooperate
• Poor general condition due to acute medical problems
• Chronic decompensated cardiac, renal, or hepatic failure
• Presence of rheumatologic, psychiatric, or neurological disorders
• Use of performance-enhancing or fatigue-reducing medications

Sponsors & Collaborators

• Istanbul Physical Medicine Rehabilitation Training and Research Hospital: lead

Study Sites (1)

Istanbul Physical Medicine Rehabilitation Training and Research Hospital

Istanbul, 31180, Turkey (Türkiye)

Location

Related Publications (4)

• Bahat G, Tufan A, Tufan F, Kilic C, Akpinar TS, Kose M, Erten N, Karan MA, Cruz-Jentoft AJ. Cut-off points to identify sarcopenia according to European Working Group on Sarcopenia in Older People (EWGSOP) definition. Clin Nutr. 2016 Dec;35(6):1557-1563. doi: 10.1016/j.clnu.2016.02.002. Epub 2016 Feb 11.

  PMID: 26922142 BACKGROUND

• Power GA, Dalton BH, Rice CL. Human neuromuscular structure and function in old age: A brief review. J Sport Health Sci. 2013 Dec;2(4):215-226. doi: 10.1016/j.jshs.2013.07.001.

  PMID: 27011872 BACKGROUND

• Karacan I, Turker KS. Exploring neuronal mechanisms of osteosarcopenia in older adults. J Physiol. 2024 Aug 9. doi: 10.1113/JP285666. Online ahead of print.

  PMID: 39119811 BACKGROUND

• Cruz-Jentoft AJ, Bahat G, Bauer J, Boirie Y, Bruyere O, Cederholm T, Cooper C, Landi F, Rolland Y, Sayer AA, Schneider SM, Sieber CC, Topinkova E, Vandewoude M, Visser M, Zamboni M; Writing Group for the European Working Group on Sarcopenia in Older People 2 (EWGSOP2), and the Extended Group for EWGSOP2. Sarcopenia: revised European consensus on definition and diagnosis. Age Ageing. 2019 Jan 1;48(1):16-31. doi: 10.1093/ageing/afy169.

  PMID: 30312372 BACKGROUND

MeSH Terms

Conditions

Sarcopenia

Condition Hierarchy (Ancestors)

Muscular Atrophy; Neuromuscular Manifestations; Neurologic Manifestations; Nervous System Diseases; Atrophy; Pathological Conditions, Anatomical; Pathological Conditions, Signs and Symptoms; Signs and Symptoms

Study Officials

• İlhan Karacan, Prof.

  Istanbul Physical Medicine Rehabilitation Training and Research Hospital

  STUDY DIRECTOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER GOV
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: M.D.

Study Record Dates

• First Submitted: July 3, 2025
• First Posted: July 15, 2025
• Study Start: April 1, 2025
• Primary Completion: July 27, 2025
• Study Completion: July 27, 2025
• Last Updated: July 30, 2025

Record last verified: 2025-07

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)