COVID-19 Knowledge, Attitudes, Practices and Perceived Risk: Cross Sectional Mixed Methods

NCT07021716 | Completed

• 1 other identifier: 24-08027786
• Study Type: observational
• Target: 148
• Locations: 1 country
• Sites: 1

Brief Summary

Knowledge, attitudes, behaviors and perceived risk highlight the importance of education translated into actions to reduce the risk of global infections. The purpose was to investigate the knowledge, attitudes and practices (KAP), and perceived risk associated with COVID-19 among patients with multiple sclerosis (MS), healthcare providers and laypeople during the first 6-months of the pandemic. A descriptive, cross-sectional, partially mixed-methods explanatory sequential design was employed, using convenience sampling. Data were collected through a demographic and a KAP questionnaires including perceived risk assessment. Quantitative data were analyzed with descriptive and inferential statistics, while qualitative comments underwent thematic analysis.

Conditions

COVID - 19; Multiple Sclerosis

Keywords

COVID; Knowledge; Attitudes; Practices

Outcome Measures

Primary Outcomes (4)

• Knowledge

  Knowledge associated with COVID-19

  6 months

• Perceived Risk

  Perceived risk for contracting COVID-19 was assessed using a 5-point scale (0=no risk at all, 1=a small risk, 2=a moderate risk, 3=a high risk, 4=Don't know). Perceived risk of COVID was assessed as a categorical variable. It was analyzed as dichotomous variable (low risk vs. moderate/high risk) and as 4-categorical variable (low risk, moderate risk, high risk and don't know). Perceived risk was assessed and analyzed in each group, patients with MS, healthcare professionals and lay people.

  6 months

• Attitudes

  Attitudes associated with COVID-19

  6 months

• Practices

  Practices associated with COVID-19

  6 months

Study Arms (3)

Patients with multiple sclerosis

Patients with multiple sclerosis answered the KAP survey providing answers to open ended questions analyzed qualitatively.

Other: No Interventions

Healthcare professionals

Healthcare professionals answered the KAP survey providing answers to open ended questions analyzed qualitatively.

Other: No Interventions

Laypeople

Laypeople answered the KAP survey providing answers to open ended questions analyzed qualitatively.

Other: No Interventions

Interventions

No Interventions OTHER

No Interventions

Healthcare professionals; Laypeople; Patients with multiple sclerosis

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The population for this study included healthcare professionals (nurses and physicians), patients with MS, and lay people from the northeast region in the USA. It included participants from New York, Connecticut and Massachusetts. A convenience sampling approach was used to enhance recruitment. The participants were recruited via blast emails through health centers, MS centers, and community resources. Data were collected via an online self-reported questionnaire from April 2020 to September 2020. The surveys were completed online via anonymous and confidential software, i.e., a 'Monkey' survey. The inclusion criteria of the study included adult people (≥18 years), consisting of patients with MS, healthcare professionals (nurses and physicians), and adult lay people. The project did not include any exclusion criteria.

Sponsors & Collaborators

• Hunter College of City University of New York: lead

Study Sites (1)

Hunter College

New York, New York, 10010, United States

Location

MeSH Terms

Conditions

COVID-19; Multiple Sclerosis; Behavior

Condition Hierarchy (Ancestors)

Pneumonia, Viral; Pneumonia; Respiratory Tract Infections; Infections; Virus Diseases; Coronavirus Infections; Coronaviridae Infections; Nidovirales Infections; RNA Virus Infections; Lung Diseases; Respiratory Tract Diseases; Demyelinating Autoimmune Diseases, CNS; Autoimmune Diseases of the Nervous System; Nervous System Diseases; Demyelinating Diseases; Autoimmune Diseases; Immune System Diseases

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: June 9, 2025
• First Posted: June 15, 2025
• Study Start: April 1, 2020
• Primary Completion: September 1, 2020
• Study Completion: December 30, 2020
• Last Updated: June 15, 2025

Record last verified: 2020-12

Locations

US (1)