Brain Attack Surveillance in Corpus Christi--Cognitive (BASIC-Cognitive)

NCT03403257 | Active Not Recruiting

• 1 other identifier: R01NS100687
• Study Type: observational
• Target: 634
• Locations: 1 country
• Sites: 1

Brief Summary

The Mexican American population in the U.S. is rapidly growing and aging. This project seeks to determine the prevalence and outcomes of cognitive impairment and dementia in Mexican Americans. It also seeks solutions to help patients with cognitive impairment and dementia and their caregivers get the resources they need.

Conditions

Dementia, Vascular; Dementia, Mixed; Dementia; Dementia Alzheimers

Keywords

Caregiving; Hispanic; Mexican American; Epidemiology; Community

Outcome Measures

Primary Outcomes (3)

• Prevalence of mild cognitive impairment and dementia in Mexican Americans and non Hispanic whites

  Prevalence estimates

  2 year data collection

• Trajectory of cognitive function in Mexican Americans and non Hispanic whites

  Change in cognitive function among subjects entered at baseline

  2 year follow-up after baseline

• Caregiver outcomes and changes over time

  Comparative caregiver outcomes among Mexican Americans and non Hispanic whites

  4 years

Secondary Outcomes (1)

• Needs and community available resources for cognitive impairment

  2 years

Study Arms (2)

Subjects with cognitive impairment

Subjects with MoCA \<26

Other: No interventions

Caregivers

Primary caregivers of subjects

Other: No interventions

Interventions

No interventions OTHER

No intervention

Caregivers; Subjects with cognitive impairment

Eligibility Criteria

• Age: 65 Years+
• Gender Eligibility Details: Self-described
• Healthy Volunteers: No
• Age Groups: Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Residents of Nueces County, Texas

You may qualify if:

• years of age or older 2. MoCA \< 26 3. Nueces County resident at least 6 months a year 4. English or Spanish speaking 5. Community dwelling or nursing home

Sponsors & Collaborators

• National Institutes of Health (NIH): collaborator
• University of Michigan: lead

Study Sites (1)

Corpus Christi Nueces County Health District

Corpus Christi, Texas, 78416, United States

Location

Related Publications (11)

• Briceno EM, Mehdipanah R, Gonzales X, Heeringa S, Levine DA, Langa KM, Garcia N, Longoria R, Morgenstern LB. Methods and Early Recruitment of a Community-Based Study of Cognitive Impairment Among Mexican Americans and Non-Hispanic Whites: The BASIC-Cognitive Study. J Alzheimers Dis. 2020;73(1):185-196. doi: 10.3233/JAD-190761.

  PMID: 31771059 RESULT

• Briceno EM, Mehdipanah R, Gonzales XF, Heeringa SG, Levine DA, Langa KM, Zahs D, Garcia N, Longoria R, Morgenstern LB. Bilingualism, assessment language, and the Montreal Cognitive Assessment in Mexican Americans. J Am Geriatr Soc. 2021 Jul;69(7):1971-1981. doi: 10.1111/jgs.17209. Epub 2021 May 7.

  PMID: 33963535 RESULT

• Mehdipanah R, Briceno EM, Gonzales XF, Heeringa SG, Levine DA, Langa KM, Garcia N, Longoria R, Morgenstern LB. Dementia care needs for individuals and caregivers among Mexican Americans and non-Hispanic Whites. Aging Ment Health. 2022 Aug;26(8):1630-1641. doi: 10.1080/13607863.2021.1925222. Epub 2021 Jun 7.

  PMID: 34096422 RESULT

• Briceno EM, Mehdipanah R, Gonzales XF, Heeringa SG, Levine DA, Langa KM, Zahs D, Garcia N, Longoria R, Vargas A, Morgenstern LB. Differential Relationships Between the Montreal Cognitive Assessment and Informant-Rated Cognitive Decline Among Mexican Americans and Non-Hispanic Whites. J Geriatr Psychiatry Neurol. 2022 Jul;35(4):555-564. doi: 10.1177/08919887211029383. Epub 2021 Jul 22.

  PMID: 34291678 RESULT

• Khan N, Garcia N, Mehdipanah R, Briceno EM, Heeringa SG, Levine DA, Gonzales XF, Langa KM, Longoria R, Morgenstern LB. Lack of Any Caregiving for Those with Dementia. J Alzheimers Dis. 2022;86(2):531-535. doi: 10.3233/JAD-215418.

  PMID: 35068465 RESULT

• Gonzales XF, Heeringa SG, Briceno EM, Mehdipanah R, Levine DA, Langa KM, Garcia N, Longoria R, Morgenstern LB. Mexican Americans Participate in Research More than Expected while non-Hispanic Whites Participate Less than Expected. J Health Care Poor Underserved. 2022;33(2):590-596. doi: 10.1353/hpu.2022.0049.

  PMID: 35574862 RESULT

• Mehdipanah R, Briceno EM, Heeringa SG, Gonzales XF, Levine DA, Langa KM, Garcia N, Longoria R, Chang W, Morgenstern LB. Neighborhood SES and Cognitive Function Among Hispanic/Latinx Residents: Why Where You Live Matters. Am J Prev Med. 2022 Oct;63(4):574-581. doi: 10.1016/j.amepre.2022.04.016. Epub 2022 Jun 9.

  PMID: 35691843 RESULT

• Becker CJ, Heeringa SG, Chang W, Briceno EM, Mehdipanah R, Levine DA, Langa KM, Gonzales XF, Garcia N, Longoria R, Springer MV, Zahuranec DB, Morgenstern LB. Differential Impact of Stroke on Cognitive Impairment in Mexican Americans and Non-Hispanic White Americans. Stroke. 2022 Nov;53(11):3394-3400. doi: 10.1161/STROKEAHA.122.039533. Epub 2022 Aug 12.

  PMID: 35959679 RESULT

• Martins-Caulfield J, Mehdipanah R, Briceno EM, Chang W, Heeringa SG, Gonzales XF, Levine DA, Langa KM, Zahuranec DB, Garcia N, Morgenstern LB. Dementia Diagnosis Unawareness and Caregiver Burden in a Multi-ethnic Cohort. J Gen Intern Med. 2025 Jul;40(10):2284-2291. doi: 10.1007/s11606-024-09333-1. Epub 2025 Jan 14.

  PMID: 39808391 DERIVED

• Morgenstern LB, Briceno EM, Mehdipanah R, Chang W, Lewandowski-Romps L, Gonzales XF, Levine DA, Langa KM, Garcia N, Khan N, Zahuranec DB, Heeringa SG. A Community-Based Study of Dementia in Mexican American and Non-Hispanic White Individuals. J Alzheimers Dis. 2024;97(2):649-658. doi: 10.3233/JAD-230729.

  PMID: 38143352 DERIVED

• Khan N, Briceno EM, Mehdipanah R, Lewandowski-Romps L, Heeringa SG, Garcia N, Levine DA, Langa KM, Morgenstern LB. A community-based study of reporting demographic and clinical information concordance between informants and cognitively impaired participants. Aging Clin Exp Res. 2023 Jul;35(7):1571-1576. doi: 10.1007/s40520-023-02435-6. Epub 2023 May 19.

  PMID: 37204754 DERIVED

MeSH Terms

Conditions

Dementia; Alzheimer Disease; Dementia, Vascular; Mixed Dementias

Condition Hierarchy (Ancestors)

Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Neurocognitive Disorders; Mental Disorders; Tauopathies; Neurodegenerative Diseases; Cerebrovascular Disorders; Intracranial Arteriosclerosis; Intracranial Arterial Diseases; Leukoencephalopathies; Arteriosclerosis; Arterial Occlusive Diseases; Vascular Diseases; Cardiovascular Diseases

Study Officials

• Lewis Morgenstern, MD

  University of Michigan

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: January 11, 2018
• First Posted: January 18, 2018
• Study Start: April 11, 2018
• Primary Completion: April 30, 2026
• Study Completion (Estimated): April 30, 2027
• Last Updated: February 17, 2026

Record last verified: 2026-02

Locations

US (1)