Thoracolumbar Fascia Thickness in Patients With Parkinson's Disease

NCT07006376 | Completed

• 1 other identifier: E-59394181-604.01-112208
• Study Type: observational
• Target: 80
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this study is to examine thoracolumbar fascia thickness, trunk flexibility, trunk control and upper extremity skills in Parkinson's disease patients. Patients between the ages of 55-80 who have been diagnosed with Parkinson's disease by a neurologist and healthy individuals with similar demographic characteristics will be included in the study as a control group. Demographic information of the individuals will be recorded and clinical evaluations will be made. Staging of Parkinson's patients will be done with the Modified Hoehn and Yahr Scale (MHRS), and disease severity will be done with the Unified Parkinson's Disease Rating Scale (UPDRS). Thoracolumbar fascia thickness of individuals in both groups will be evaluated with ultrasonography, trunk flexibility with the Active Trunk Range of Motion Assessment and Sit-Reach test, trunk functions with the Trunk Impairment Scale, and manual skills with the Purdue Pegboard Test.

Conditions

Parkinson Disease

Outcome Measures

Primary Outcomes (3)

• Ultrasonography Measurement

  The thickness of the Thoracolumbar Fascia will be measured by ultrasonography at the level of the L3 lumbar vertebra and using a predefined standard protocol.

  Baseline

• Range of Motion Assessment

  Active trunk ranges of motion will be assessed during flexion/extension, rotation, and lateral flexion using a universal goniometer.

  Baseline

• Sit and Reach Test

  For this test, a tape measure will be fixed to a table at the exact level of the subjects' feet. Subjects will sit in front of the table with bare feet and legs straight. Then, they will slowly extend forward as far as possible, keeping their hands together and without bending their knees. During this extension, attention will be paid to the subjects' straight backs and to avoid sudden movements.

  Baseline

Study Arms (2)

Study Group

Patients with Parkinson's Disease

Control Group

Healthy individuals with similar demographic characteristics

Eligibility Criteria

• Age: 55 Years - 80 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients with Parkinson's Disease

You may qualify if:

• Age between 50 and 80
• Mini Mental State Examination (MMSE) score between 24 and 30
• Diagnosed with Parkinson's by a neurologist
• MH\&Y stage 2-3

You may not qualify if:

• Inability to communicate verbally
• Use of walking aids
• Elderly people with severe visual impairment, neurological disorders and/or congestive heart failure
• Older adults in whom exercise is not recommended.

Sponsors & Collaborators

• Ankara University: lead

Study Sites (1)

Atılım University

Ankara, Turkey (Türkiye)

Location

Related Publications (2)

• De Coninck K, Hambly K, Dickinson JW, Passfield L. Measuring the morphological characteristics of thoracolumbar fascia in ultrasound images: an inter-rater reliability study. BMC Musculoskelet Disord. 2018 Jun 1;19(1):180. doi: 10.1186/s12891-018-2088-5.

  PMID: 29859080 RESULT

• Yerli S, Yinanc SB, Yagci G, Erbahceci F, Ozcakar L. Thoracolumbar fascia and chronic low back pain in idiopathic lumbar scoliosis: an ultrasonographic study. Eur Spine J. 2024 Jun;33(6):2469-2475. doi: 10.1007/s00586-024-08266-x. Epub 2024 Apr 23.

  PMID: 38653872 RESULT

MeSH Terms

Conditions

Parkinson Disease

Condition Hierarchy (Ancestors)

Parkinsonian Disorders; Basal Ganglia Diseases; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Movement Disorders; Synucleinopathies; Neurodegenerative Diseases

Study Officials

• Ayla Fil Balkan, Assoc Prof

  Hacettepe University

  STUDY CHAIR

• Gül Yalçın Çakmaklı, Assoc Prof

  Hacettepe University

  STUDY CHAIR

• Süleyman Korkusuz, Assist.Prof

  Atılım University

  STUDY CHAIR

• Büşra Seçkinoğulları Korkusuz, PhD

  Ankara University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: May 28, 2025
• First Posted: June 5, 2025
• Study Start: June 11, 2025
• Primary Completion: August 20, 2025
• Study Completion: September 20, 2025
• Last Updated: March 25, 2026

Record last verified: 2025-07

Locations

TU (1)