Exercise Management in Parkinson's Disease

NCT07302386 | Recruiting

• 1 other identifier: 949
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this study is to examine the benefits that individuals with Parkinson's disease will gain from the rehabilitation program by enabling them to manage their exercise times independently using telerehabilitation method. The main research questions examined in this study are as follows:

• Are the improvements in quality of life, walking speed and changes in functionality parameters achieved by individuals with Parkinson's disease through managing their own exercise plans as effective as those achieved through a supervised exercise programme?
• Is it effective for Parkinson's patients to manage their own exercise plans in improving their adherence to exercise?

Conditions

Parkinson Disease (PD)

Outcome Measures

Primary Outcomes (7)

• Change in motor impairment

  The Unified Parkinson's Disease Rating Scale (UPDRS) is used to determine the symptoms and clinical severity of PD. The UPDRS-III subscore will be used to assess changes in motor impairment.

  Baseline and the end of the 8 weeks exercise program

• Change in behavioral regulations in exercise

  Behavioral Regulations in Exercise Questionnaire-2 consists of 19 items and five subscales. The subscales consist of external regulation, internalized regulation, defined regulation, internal regulation and lack of motivation. It is a 5-point Likert-type scale scored between 0-4.

  Baseline and the end of the 8 weeks exercise program

• Change in lower extremity power and endurance

  Five Times Sit to Stand Test will be used to measure repetitive movement performance. The patient will be asked to sit down and stand up 5 times as quickly as possible, and this time will be recorded in seconds.

  Baseline and the end of the 8 weeks exercise program

• Change in walking speed

  10-Meter Walk Test will be applied to assess walking speed. The first 2 meters of the 14-meter distance are allocated for acceleration, the last 2 meters for deceleration, and the time taken to walk the 10-meter distance is recorded. Walking speed is calculated in meters per second.

  Baseline and the end of the 8 weeks exercise program

• Change in mobility

  Timed Up and Go Test is used to assess mobility, balance, and risk of falling. The patient is asked to stand up from a chair, walk around a cone 3 meters away, and return to sit on the chair. The total time is recorded using a stopwatch.

  Baseline and the end of the 8 weeks exercise program

• Change in body position

  Activities-Specific Balance Confidence is a measure that assesses a person's level of confidence in their balance both indoors and outdoors. It consists of 16 different activities and is rated on a scale from no confidence (-0) to complete confidence (-100). A higher score indicates a greater level of confidence in balance.

  Baseline and the end of the 8 weeks exercise program

• Change in quality of life

  The Parkinson's Disease Quality of Life Questionnaire (PDQ-39) will be used to assess quality of life. It consists of 39 items and is composed of 8 sub-parameters: mobility, activities of daily living, stigma, social support, communication, emotional well-being, and physical discomfort. As the score increases, quality of life deteriorates.

  Baseline and the end of the 8 weeks exercise program

Study Arms (2)

Self-Management Group

EXPERIMENTAL

The self-management group will perform the exercise programme prescribed by the physical therapist and tailored to the patient's needs via a web-based system twice a week for eight weeks, at a time of their choosing.

Other: Telerehabilitation

Telerehabilitation Group

ACTIVE COMPARATOR

Telerehabilitation group will perform the exercise programme prescribed by the physical therapist and tailored to the patient's needs via a web-based system twice a week for eight weeks.

Other: Telerehabilitation

Interventions

Telerehabilitation OTHER

The exercises will consist of stretching, strengthening, balance, and neuromotor exercises that the patient can perform independently at home.

Self-Management Group; Telerehabilitation Group

Eligibility Criteria

• Age: 45 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Diagnosed with Idiopathic Parkinson's Disease by a neurologist according to the UK Parkinson's Disease Association Brain Bank clinical diagnostic criteria
• H\&Y Stage I-III
• Montreal Cognitive Assessment Scale MoCA≥21
• Having the necessary technological devices to participate in telerehabilitation
• Being able to walk 100 meters
• Having at least a primary school diploma

You may not qualify if:

• Presence of a neurological disorder other than Parkinson's disease
• Presence of any cardiopulmonary or musculoskeletal problem that affects gait and balance
• Receiving Deep Brain Stimulation (DBS) treatment or having undergone DBS surgery in the past
• Presence of vision or hearing problems

Sponsors & Collaborators

• Marmara University: lead

Study Sites (1)

Marmara University

Maltepe, Istanbul, 34852, Turkey (Türkiye)

RECRUITING

Related Publications (7)

• Franchignoni F, Giordano A, Ronconi G, Rabini A, Ferriero G. Rasch validation of the Activities-specific Balance Confidence Scale and its short versions in patients with Parkinson's disease. J Rehabil Med. 2014 Jun;46(6):532-9. doi: 10.2340/16501977-1808.

  PMID: 24687205 BACKGROUND

• Huang SL, Hsieh CL, Wu RM, Tai CH, Lin CH, Lu WS. Minimal detectable change of the timed "up & go" test and the dynamic gait index in people with Parkinson disease. Phys Ther. 2011 Jan;91(1):114-21. doi: 10.2522/ptj.20090126. Epub 2010 Oct 14.

  PMID: 20947672 BACKGROUND

• Dean CM, Richards CL, Malouin F. Walking speed over 10 metres overestimates locomotor capacity after stroke. Clin Rehabil. 2001 Aug;15(4):415-21. doi: 10.1191/026921501678310216.

  PMID: 11518442 BACKGROUND

• Duncan RP, Leddy AL, Earhart GM. Five times sit-to-stand test performance in Parkinson's disease. Arch Phys Med Rehabil. 2011 Sep;92(9):1431-6. doi: 10.1016/j.apmr.2011.04.008.

  PMID: 21878213 BACKGROUND

• Goetz CG, Fahn S, Martinez-Martin P, Poewe W, Sampaio C, Stebbins GT, Stern MB, Tilley BC, Dodel R, Dubois B, Holloway R, Jankovic J, Kulisevsky J, Lang AE, Lees A, Leurgans S, LeWitt PA, Nyenhuis D, Olanow CW, Rascol O, Schrag A, Teresi JA, Van Hilten JJ, LaPelle N. Movement Disorder Society-sponsored revision of the Unified Parkinson's Disease Rating Scale (MDS-UPDRS): Process, format, and clinimetric testing plan. Mov Disord. 2007 Jan;22(1):41-7. doi: 10.1002/mds.21198.

  PMID: 17115387 BACKGROUND

• Fahn S. Unified Parkinson's disease rating scale. Recent developments in Parkinson's disease. 1987:153-63.

  BACKGROUND

• Bloem BR, Okun MS, Klein C. Parkinson's disease. Lancet. 2021 Jun 12;397(10291):2284-2303. doi: 10.1016/S0140-6736(21)00218-X. Epub 2021 Apr 10.

  PMID: 33848468 BACKGROUND

MeSH Terms

Conditions

Parkinson Disease

Interventions

Telerehabilitation

Condition Hierarchy (Ancestors)

Parkinsonian Disorders; Basal Ganglia Diseases; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Movement Disorders; Synucleinopathies; Neurodegenerative Diseases

Intervention Hierarchy (Ancestors)

Rehabilitation; Aftercare; Continuity of Patient Care; Patient Care; Therapeutics; Health Services; Health Care Facilities Workforce and Services; Telemedicine; Delivery of Health Care; Patient Care Management; Health Services Administration

Study Officials

• Semra Oğuz, PhD

  Marmara University

  STUDY DIRECTOR

Central Study Contacts

Gökçe Kartal

CONTACT

+905055624837; gokcekrtl2@gmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: MSc, PT

Study Record Dates

• First Submitted: December 11, 2025
• First Posted: December 24, 2025
• Study Start: December 15, 2025
• Primary Completion (Estimated): November 7, 2026
• Study Completion (Estimated): December 2, 2026
• Last Updated: March 31, 2026

Record last verified: 2026-03

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)