NCT06896032

Brief Summary

The purpose of this study Will investigate and compare the effects of retro-walking and forward-walking underwater treadmill training on pain, function and ROM in subjects with chronic knee OA

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
60

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Mar 2025

Shorter than P25 for not_applicable

Geographic Reach
1 country

2 active sites

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

February 22, 2025

Completed
1 month until next milestone

First Posted

Study publicly available on registry

March 26, 2025

Completed
4 days until next milestone

Study Start

First participant enrolled

March 30, 2025

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 30, 2025

Completed
25 days until next milestone

Study Completion

Last participant's last visit for all outcomes

July 25, 2025

Completed
Last Updated

April 16, 2025

Status Verified

March 1, 2025

Enrollment Period

3 months

First QC Date

February 22, 2025

Last Update Submit

April 13, 2025

Conditions

Keywords

Knee Osteoarthritis

Outcome Measures

Primary Outcomes (2)

  • Pain intensity

    Pain intensity will be measured by visual analog scale (VAS. ). It is line with worst pain at one end and no pain at the other end

    up to three monthes

  • knee disability

    knee disablity will be measured by The Western Ontario and McMaster Universities osteoarthritis index. The WOMAC is a self-administered instrument containing 24 items measuring 3 subscales: physical function (17 items), pain (5 items), and stiffness (2 items).Scores range from 0 to 96 for the total WOMAC where 0 represents the best health status and 96 the worst possible status.

    up to three months

Secondary Outcomes (1)

  • knee range of motion

    up to three months

Study Arms (3)

group A (experimental1)

EXPERIMENTAL

forward walking group

Other: physical therapy intervention

group B (experimental 2)

EXPERIMENTAL

retro walking group

Other: physical therapy intervention

group c

OTHER

control group

Other: physical therapy intervention

Interventions

retro-walking and forward-walking underwater treadmill training

Also known as: hydro therapy, aquatic therapy
group A (experimental1)group B (experimental 2)group c

Eligibility Criteria

Age40 Years - 60 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • patients with chronic knee OA.
  • Age ranges from 40-60 years old of both genders.
  • body mass index (BMI) 25- 35kg/m2.
  • The degree of osteoarthritis was mild or moderate and have a Kellgren- Lawrence radiographic grade of of1-3.
  • unilateral knee osteoarthritis involvement.

You may not qualify if:

  • hydrophobia.
  • pregnancy.
  • infection.
  • psychiatric disorder.
  • haemorrhagic diathesis.
  • cardiac pacemaker.
  • all Subjects with deformity of hip, knee \& ankle.
  • any CNS or PNS involvement.
  • recent steroidal or intraarticular injections (3 months).
  • systemic inflammatory disease and bone malignancy.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

cairo U

Cairo, Cairo Governorate, 02, Egypt

ENROLLING BY INVITATION

cairo U

Cairo, Cairo Governorate, 02, Egypt

RECRUITING

MeSH Terms

Conditions

Osteoarthritis, KneeOsteoarthritis

Interventions

Aquatic Therapy

Condition Hierarchy (Ancestors)

ArthritisJoint DiseasesMusculoskeletal DiseasesRheumatic Diseases

Intervention Hierarchy (Ancestors)

HydrotherapyPhysical Therapy ModalitiesTherapeuticsRehabilitation

Central Study Contacts

nourhan atwa said, bacalora

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
INVESTIGATOR, OUTCOMES ASSESSOR
Masking Details
Opaque sealed envelope
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: Retro walking and forward walking training exercise
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
physical therapist

Study Record Dates

First Submitted

February 22, 2025

First Posted

March 26, 2025

Study Start

March 30, 2025

Primary Completion

June 30, 2025

Study Completion

July 25, 2025

Last Updated

April 16, 2025

Record last verified: 2025-03

Locations