A Mobile App For Drug Dosage Calculation In The Context Of Pediatric And Adult Resuscitation: A Cross-Over Randomized Controlled Trial

NCT06804915 | Completed

• 1 other identifier: 2025-922
• Study Type: interventional
• Target: 24
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to investigate whether the use of the EZResus app by physicians and nurses reduces medication errors in simulated adult and pediatric resuscitation scenarios compared to the use of standard protocols. This study is a randomized controlled crossover trial with two groups comparing the use of EZResus app with standard protocol in four simulated resuscitation scenarios. The participants will form resuscitation teams, each including an attending physician and two nurses responsible for the preparation and administration of medications. Each team will conduct one adult and one pediatric resuscitation scenario using the EZResus application, along with one adult and one pediatric resuscitation scenario following standard protocols.The teams will be individually randomized to start the scenarios either with or without the medical application using sealed envelopes. The participants will be recruited from one regional hospital (Haut-Richelieu hospital) and one university hospital (Charles LeMoyne Hospital).

Conditions

Mobile App Use in Resuscitation

Keywords

mobile app; smartphone; resuscitation; drug errors

Outcome Measures

Primary Outcomes (1)

• Drug administration appropriate or not

  In this study, the drug administration will be classified as either appropriate or inappropriate, with inappropriate administration being defined by one or more of the following criterias : * the administration of the incorrect medication * the use of an inappropriate route of administration * a prescribed dosage that deviates by more than 10% from the appropriate dose (as defined in the medication tables in appendix) or * an administered dosage that deviates by more than 10% from the prescribed dosage * The omission of a medication considered essential for treatment.

  duration of the simulation: 15-25 minutes per scenario

Secondary Outcomes (10)

• Drug administration appropriate or not - prescription phase

  duration of the simulation: 15-25 minutes per scenario

• Drug administration appropriate or not

  duration of the simulation: 15-25 minutes per scenario

• time to drug prescription

  duration of the simulation: 15-25 minutes per scenario

• time for drug preparation

  duration of the simulation: 15-25 minutes per scenario

• time to drug delivery

  duration of the simulation: 15-25 minutes per scenario

Study Arms (2)

Medical calculator application use (EzResus)

EXPERIMENTAL

Participants (physicians and nurses) will be allowed to use a medical calculator application called EzResus. They will receive a 5-minute training prior to the simulations. Participants are also allowed to use other ressources, such as local protocols, medication administration guide.

Behavioral: simulation

Standard care

ACTIVE COMPARATOR

Participants are also allowed to use the ressources they use in their practice, apart from a medical calculator application. They are allowed to use local protocols, medication administration guides, medical mobile apps that don't calculate drug doses.

Behavioral: simulation

Interventions

simulation BEHAVIORAL

Each team of physician and nurses will participate in 4 scenarios: 2 adult, 2 pediatric. In each scenario, physician and nurses will have a clinical description of the scenario with the age and weight of each patient. The simulations will be conducted at the clinical simulation laboratory at Jean-Marc Lepage Pavilion of the University of Sherbrooke using high-fidelity mannequins. SimMan 3GPus will be used for adult scenarios and SimJunior for pediatric scenarios, both from Laerdal company. Participants will receive a briefing containing key information about the scenario and the patient just before starting the simulation. During the scenarios, the physician is expected to prescribe medications by mentioning the name, the dose and the route of administration of every medication. Moreover, if multiple dilution for a medication is possible, the physician is expected to mention the desired dilution.

Medical calculator application use (EzResus); Standard care

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• Emergency physicians or emergency nurses working in the resuscitation room and working in one of the two eligible hospital centers.

You may not qualify if:

• Being part of the research team or affiliated in any way with the EZResus team.

Sponsors & Collaborators

• Université de Sherbrooke: lead

Study Sites (1)

Hôpital Charles-Le Moyne

Greenfield Park, Quebec, J3V 6M6, Canada

Location

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Emergency medicine and Pediatric emergency medicine specialist

Model Details: Each team will conduct one adult and one pediatric resuscitation scenario using the EZResus application, along with one adult and one pediatric resuscitation scenario following standard protocols.The teams will be individually randomized to start the scenarios either with or without the medical application using sealed envelopes. Standard protocol is defined as standard care using any resources usually used by professionals, except for medical calculator applications.

Study Record Dates

• First Submitted: January 10, 2025
• First Posted: February 3, 2025
• Study Start: January 10, 2025
• Primary Completion: January 15, 2025
• Study Completion: January 15, 2025
• Last Updated: February 3, 2025

Record last verified: 2025-01

Data Sharing

• IPD Sharing: Will share

Locations

CA (1)