External Oblique Intercostal Block vs Subcostal Transversus Abdominis Plane Block in Open Nephrectomy

NCT06778707 | Active Not Recruiting DMC

• 1 other identifier: 36264PR998/12/24
• Study Type: interventional
• Target: 80
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of the study is to compare the analgesic efficacy of external oblique intercostal block vs subcostal transversus abdominis plane block in patients undergoing open nephrectomy.

Conditions

Analgesia , Open Renal Surgeries

Keywords

External Oblique Intercostal Block; Subcostal Transversus Abdominis Plane Block

Outcome Measures

Primary Outcomes (1)

• Total morphine consumption in the first postoperative 24 hour

  Total morphine consumption in the first postoperative 24 hour

  first postoperative 24 hour

Secondary Outcomes (2)

• NRS when patient reach recovery room and at 2 hour, 6 hour, 12 hour, 18 hour and 24 hour

  when patient reach recovery room and at 2 hour, 6 hour, 12 hour, 18 hour and 24 hour

• Total intraoperative fentanyl consumption with exclusion of fentanyl used in induction

  intraoperative

Study Arms (2)

group E

ACTIVE COMPARATOR

This group of patients will receive external oblique intercostal block in supine position. A high-frequency linear transducer will be placed in sagittal plane between the midclavicular and anterior axillary line at the level of the 6 to 8th rib. The pointing mark of the probe will be directed cranially and may be slightly tilted medially for better identification of external oblique muscle and intercostal muscles. After sterilization of skin and through the in-plane technique directing from cranial to caudal, a needle will be used to pierce the skin, subcutaneous tissue then external oblique muscle to hydrodissect the fascial plane between external oblique muscle and intercostal muscles with 25 ml bupivacaine 0.25 % and 4 mg dexamethasone added to it.

Procedure: External Oblique Intercostal Block

group T

ACTIVE COMPARATOR

Subcostal transversus abdominis plane block will be applied to this group and patients will be supine. A high-frequency linear transducer will be placed directly below and along costal margin. After sterilization of skin, with in-plane technique and from lateral to medial, a needle will be used to pierce the skin, subcutaneous tissue then rectus muscle and 25 ml of 0.25 % bupivacaine with 4 mg dexamethasone will be injected between rectus muscle and transversus abdominis muscle.

Procedure: Subcostal Transversus Abdominis Plane Block

Interventions

External Oblique Intercostal Block PROCEDURE

In group E, a needle will be used to pierce the skin, subcutaneous tissue then external oblique muscle to hydrodissect the fascial plane between external oblique muscle and intercostal muscles with 25 ml bupivacaine 0.25 % and 4 mg dexamethasone added to it.

group E

Subcostal Transversus Abdominis Plane Block PROCEDURE

In group T, a needle will be used to pierce the skin, subcutaneous tissue then rectus muscle and 25 ml of 0.25 % bupivacaine with 4 mg dexamethasone will be injected between rectus muscle and transversus abdominis muscle.

group T

Eligibility Criteria

• Age: 21 Years - 60 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Patients who will be included in the study age from 21 to 60 years, both male and female, with American Society of Anesthesiologists (ASA) Physical Status Classification System I-III.

You may not qualify if:

• Any patient refuses to participate, has bleeding or coagulation disorders, hepatic dysfunction, psychiatric diseases, on chronic opioid use, with history of allergy to local anesthetics and has infection at the needle entry point will be excluded.

Sponsors & Collaborators

• Tanta University: lead

Study Sites (1)

Tanta University

Tanta, 1234, Egypt

Location

Related Publications (1)

• 1.Bansal P, Sultania N, Mittal T. External oblique intercostal block in open nephrectomy patients-A zenith in analgesia for anterolateral upper abdominal surgeries: A case series. Asian Journal of Medical Sciences. 2024;15(2):264-8.

  BACKGROUND

Related Links

• https://ajmsjournal.info/index.php/AJMS/article/view/382?articlesBySimilarityPage=15

MeSH Terms

Conditions

Agnosia

Condition Hierarchy (Ancestors)

Perceptual Disorders; Neurobehavioral Manifestations; Neurologic Manifestations; Nervous System Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• Ahmed A Abdelwahed, lecturer

  Tanta University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, INVESTIGATOR
• Masking Details: double blinded prospective
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Lecturer at anesthesia & surgical ICU & Pain Medicine

Study Record Dates

• First Submitted: January 10, 2025
• First Posted: January 16, 2025
• Study Start: January 5, 2025
• Primary Completion: June 30, 2025
• Study Completion: August 20, 2025
• Last Updated: January 16, 2025

Record last verified: 2025-01

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL
• Time Frame: data will be available after finishing the study within one year
• Access Criteria: google scholar

Locations

EG (1)