Ultrasound Guided Erector Spinae Plane Block vs External Oblique Intercostal Plane Block for Nephrectomy

NCT06048744 | Completed

• 1 other identifier: 9/2023ANET1-2
• Study Type: interventional
• Target: 25
• Locations: 1 country
• Sites: 1

Brief Summary

The patients will be randomly allocated into two equal groups using a computer program. Group A: will receive U S guided external oblique intercostal block after induction. Group B: Patients will receive US guided erector spine block after induction.

Conditions

Post Operative Pain

Outcome Measures

Primary Outcomes (1)

• time for first rescue analgesia

  hours

  day 0

Secondary Outcomes (2)

• visual analogue score VAS score

  24 hours

• the number of rescue analgesics

  24hours

Study Arms (2)

external oblique intercostal block

ACTIVE COMPARATOR

After induction of general anesthesia, external oblique intercostal blocks will be performed with patients positioned in the supine position with their ipsilateral arm abducted. A 14-15 MHz linear ultrasound transducer (Sono-Site) was placed in the sagittal plane between the midclavicular and anterior axillary lines at the level of sixth rib. 30 ml of bupivacaine 0.25% will be administered incrementally. The drug will be injected after a negative aspiration into the plane deep to the external oblique muscle and superficial to the sixth and seventh ribs and their associated intercostal muscles.

Procedure: external oblique intercostal block

Erector Spine Block

ACTIVE COMPARATOR

After induction of general anesthesia, patients will be positioned in the lateral position . A linear ultrasound transducer will be placed on the midline to identify the T8 spinous process. From this position, the ultrasound transducer was moved 2-3 cm laterally to visualize the hyperechoic line of the T8 transverse process with its associated acoustic shadow inferiorly, and the overlying erector spinae muscle superiorly. 30 ml 0.25% bupivacaine will be injected.

Procedure: Erector Spine block

Interventions

external oblique intercostal block PROCEDURE

U S guided external oblique intercostal block after induction.

external oblique intercostal block

Erector Spine block PROCEDURE

US guided erector spine block after induction

Erector Spine Block

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Eligible patients will be older than 21 years old with American society of anesthesiology ASA physical status I\& II\&III scheduled for elective (Subcostal) Nephrectomy

You may not qualify if:

• Patients who are:
• Uncooperative.
• Having allergy to any of the study drugs.
• Known abuse of alcohol or medication.
• Having Local infection at the site of injection or systemic infection.
• Pregnancy.
• With coagulation disorders or on anticoagulation therapy.

Sponsors & Collaborators

• Menoufia University: lead

Study Sites (1)

Menoufia university

Cairo, Shibin Elkom, Egypt

Location

MeSH Terms

Conditions

Pain, Postoperative

Condition Hierarchy (Ancestors)

Postoperative Complications; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Pain; Neurologic Manifestations; Signs and Symptoms

Study Officials

• AMAL G SAFAN, MD

  Menoufia University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: lecturer of anaethesia

Study Record Dates

• First Submitted: September 11, 2023
• First Posted: September 21, 2023
• Study Start: September 1, 2023
• Primary Completion: December 20, 2023
• Study Completion: January 25, 2024
• Last Updated: January 26, 2024

Record last verified: 2024-01

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)