Comparison of the Effects of External Oblique Intercostal Plane Block, Subcostal Transverse Abdominis Plane Block, and Their Combination in the Management of Postoperative Pain in Laparoscopic Cholecystectomy Surgery
1 other identifier
interventional
105
0 countries
N/A
Brief Summary
This study aims to compare the efficacy of Subcostal Transversus Abdominis Plan Block, External Oblique Intercostal Plan Block and the combination of these two blocks, which are used in anesthesiology practice for postoperative pain in laparoscopy cholecystectomy surgery.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for not_applicable
Started Sep 2025
Shorter than P25 for not_applicable
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
July 31, 2025
CompletedFirst Posted
Study publicly available on registry
September 18, 2025
CompletedStudy Start
First participant enrolled
September 23, 2025
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 10, 2025
CompletedStudy Completion
Last participant's last visit for all outcomes
December 31, 2025
CompletedSeptember 18, 2025
July 1, 2025
3 months
July 31, 2025
September 17, 2025
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Postoperative Analgesic Consumption
The opioid consumption via patient controlled analgesia (PCA) in 24 hours postoperatively
24 hours postoperatively
Secondary Outcomes (1)
Postoperative Pain Scores
up to 24 hours after surgery
Study Arms (3)
Group 1: subcostal transversus abdominis plane block
ACTIVE COMPARATORThis group will receive 30 ml 0.25% of bupivacaine for the subcostal transversus abdominis plane block prior to surgery.
Group 2: external oblique intercostal plane block
ACTIVE COMPARATORThis group will receive 30 ml 0.25% of bupivacaine for the external oblique intercostal plane block prior to surgery.
Group 3: subcostal transversus abdominis and external oblique intercostal plane block combination
ACTIVE COMPARATORThis group will receive 15 ml 0.25% of bupivacaine for the external oblique intercostal plane block, in combination with 15 ml 0.25% of bupivacaine for the subcostal transversus abdominis plane block prior to surgery.
Interventions
Under ultrasound guidance, 30 ml of bupivacaine is injected along the fascia of transversus abdominis muscle.
Under ultrasound guidance, 30 ml of bupivacaine is injected between the fascias of external oblique and intercostal muscles.
The combination of the two blocks will be applied in 15 ml of volume for each.
Eligibility Criteria
You may qualify if:
- Patients scheduled for laparoscopic cholecystectomy surgery
- Patients aged between 18 to 80 years
- Having an anesthesiology risk assessment of ASA I, II, or III
You may not qualify if:
- Patients who do not give written and oral consent
- Patients with coagulopathy
- History of allergic reaction or intoxication by local anesthetics
- Severe organ failure
- Mental retardation or illiteracy
- Presence of infection on the injection site
- Pregnancy
- Patients whom the procedure is extended to open cholecystectomy
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- DOUBLE
- Who Masked
- PARTICIPANT, OUTCOMES ASSESSOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- MD
Study Record Dates
First Submitted
July 31, 2025
First Posted
September 18, 2025
Study Start
September 23, 2025
Primary Completion
December 10, 2025
Study Completion
December 31, 2025
Last Updated
September 18, 2025
Record last verified: 2025-07
Data Sharing
- IPD Sharing
- Will not share