The Application of Multimodal Ultrasound Imaging in Carpal Tunnel Syndrome

NCT06766370 | Not Yet Recruiting

• 1 other identifier: 2024-796-01
• Study Type: observational
• Target: 40
• Locations: 0 countries
• Sites: N/A

Brief Summary

The aim of this study is to explore the application value of multimodal ultrasound parameters in the diagnosis and treatment follow-up of Carpal Tunnel Syndrome.

Conditions

Carpal Tunnel Syndrome (CTS)

Keywords

ultrasound

Outcome Measures

Primary Outcomes (1)

• Boston Carpal Tunnel Syndrome Questionnaire ，BCTQ

  The Boston Carpal Tunnel Score is a patient-reported questionnaire that examines symptom severity and overall functional status of patients with carpal tunnel syndrome. The Symptom Severity Scale (SSS) with 11 questions is scored on a Likert scale of 1-5 and the Functional Status Scale (FSS) with 8 questions is scored from 1-5 with 1 as no difficulty and 5 as difficult.The higher scores mean a worse outcome.

  1,3,6,12 months

Secondary Outcomes (2)

• the patient's sensory nerve conduction velocity (SNCV)

  3,6,12months

• the patient's distal motor latency (DML).

  3,6,12months

Interventions

Ultrasound-guided nerve hydrodissection treatment PROCEDURE

Under ultrasound guidance, a mixed solution of corticosteroids and local anesthetics is injected around the nerve, followed by release of the transverse carpal ligament.

Eligibility Criteria

• Age: 18 Years - 70 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

This study primarily utilizes ultrasound multimodal imaging to observe the changes in multiple parameter indicators before and after the treatment of nerve hydrodissection combined with transverse carpal ligament release in patients clinically diagnosed with mild to moderate Carpal Tunnel Syndrome.

You may qualify if:

• Age between 18 and 70 years;
• Presence of sensory abnormalities and motor dysfunction in the median nerve distribution area;
• Positive Tinel's sign or Phalen's test;
• Neurophysiological examination consistent with mild to moderate Carpal Tunnel Syndrome.-

You may not qualify if:

• Severe Carpal Tunnel Syndrome;
• Concurrent rheumatic, metabolic, systemic, or other systemic diseases;
• Concurrent cervical spondylosis or other peripheral neuropathies;
• Wrist joint trauma, surgery, space-occupying lesions, or nerve itself with space-occupying lesions;
• Concurrent malignant tumors or severe cardiopulmonary diseases;
• History of previous wrist surgery or injections;
• Pregnancy;
• Allergy to corticosteroids or local anesthetics.-

Sponsors & Collaborators

• The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School: lead

MeSH Terms

Conditions

Carpal Tunnel Syndrome

Condition Hierarchy (Ancestors)

Median Neuropathy; Mononeuropathies; Peripheral Nervous System Diseases; Neuromuscular Diseases; Nervous System Diseases; Nerve Compression Syndromes; Cumulative Trauma Disorders; Sprains and Strains; Wounds and Injuries

Central Study Contacts

Nanjing Trum Tower Hospital

CONTACT

15651890325; weijing_zhang@163.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 1 Year
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School

Study Record Dates

• First Submitted: December 22, 2024
• First Posted: January 9, 2025
• Study Start: February 1, 2025
• Primary Completion: December 1, 2025
• Study Completion (Estimated): December 1, 2028
• Last Updated: January 9, 2025

Record last verified: 2025-01

Data Sharing

• IPD Sharing: Will not share