Effects of Kaltenborn and Mulligan Mobilisation in Patients With Carpal Tunnel Syndrome.

NCT06687018 | Recruiting

• 1 other identifier: REC/RCR & AHS/24/0129
• Study Type: interventional
• Target: 48
• Locations: 1 country
• Sites: 1

Brief Summary

Carpal Tunnel Syndrome is the most common mononeuropathy that results from the compression of median nerve in carpal tunnel, leading to entrapment neuropathy. The symptoms become aggravated during drawing, typing or playing video games. The aim of study will be to compare the effects of Kaltenborn and Mulligan mobilisation on pain, disability and hand function in patients with carpal tunnel syndrome.

Conditions

Carpal Tunnel Syndrome (CTS)

Keywords

Kaltenborn, Mulligan, Pain, Disability, Hand Function, CTS

Outcome Measures

Primary Outcomes (2)

• Numeric Pain Rating Scale

  Changes from baseline, Numeric Rating Scale (NRS) is the most commonly used scale in which the pain rate ranges from 0 (no pain) to 10 (worst pain). The NPRS has validity of 0.86 to 0.95 and reliability of 0.96.

  4 weeks

• Boston Carpal Tunnel Questionnaire

  Questionnaire used to assess functional status and symptom severity. There are two subscales in BCTQ. The Functional Status Scale evaluates hand function, whereas the Symptom Severity Scale (SSS) provides PRO data on the degree of symptoms. Eleven items make up the Symptom Severity scale, which rates symptoms related to pain, paresthesia, numbness, weakness, and grasping trouble. Eight items make up the Functional Status Scale (FSS), which evaluates functional deficiencies. Form 1 (no symptoms/difficulties) to 5 (worst symptoms/cannot do the task at all) each item is graded.(20). In BCQT, SSS has reliability 0.89 and FSS has 0.93.

  4 weeks

Study Arms (2)

Kaltenborn mobilisation

EXPERIMENTAL

Kaltenborn mobilisation along with conventional treatment.

Other: Kaltenborn mobilisation

Mulligan mobilisation

ACTIVE COMPARATOR

Mulligan mobilisation along with conventional treatment.

Other: Mulligan mobilisation

Interventions

Kaltenborn mobilisation OTHER

Kaltenborn mobilisation Grade 3 along with common treatment for 3 minutes, repeated 3 sets with rest of 1 minutes, three sessions per week for four weeks. Conventional treatment comprises a hot pack for 10 minutes, SWD for 5 minutes, and nerve and tendon gliding exercises.

Kaltenborn mobilisation

Mulligan mobilisation OTHER

Mulligan mobilisation with 10 repetitions with 3 sets and three sessions per week for four weeks. Conventional treatment comprises a hot pack for 10 minutes, SWD for 5 minutes, and nerve and tendon gliding exercises

Mulligan mobilisation

Eligibility Criteria

• Age: 20 Years - 45 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Both genders between 20 and 45 years of age
• Individuals having localized pain, tingling and numbness in the median nerve distribution
• Positive Tinel sign and positive Phalen's test

You may not qualify if:

• Any sensory and/or motor deficit in either the ulnar or radial nerve traumatic neck injury
• Previous hand surgery or trauma or cervical radiculopathy
• Systemic disease e.g. diabetes mellitus or thyroid disease or rheumatoid arthritis

Sponsors & Collaborators

• Riphah International University: lead

Study Sites (1)

Ejaz Hospital

Lahore, Punjab Province, Pakistan

RECRUITING

Related Publications (6)

• Bougea A, Zambelis T, Voskou P, Katsika PZ, Tzavara C, Kokotis P, Karandreas N. Reliability and Validation of the Greek Version of the Boston Carpal Tunnel Questionnaire. Hand (N Y). 2018 Sep;13(5):593-599. doi: 10.1177/1558944717725379. Epub 2017 Aug 20.

  PMID: 28825339 BACKGROUND

• Abdolrazaghi HA, Khansari M, Mirshahi M, Ahmadi Pishkuhi M. Effectiveness of Tendon and Nerve Gliding Exercises in the Treatment of Patients With Mild Idiopathic Carpal Tunnel Syndrome: A Randomized Controlled Trial. Hand (N Y). 2023 Mar;18(2):222-229. doi: 10.1177/15589447211006857. Epub 2021 Apr 15.

  PMID: 33855879 BACKGROUND

• Exelby L. Peripheral mobilisations with movement. Man Ther. 1996 Jun;1(3):118-126. doi: 10.1054/math.1996.0259.

  PMID: 11440498 BACKGROUND

• Spagnoli AM, Fino P, Fioramonti P, Sanese G, Scuderi N. Bifid median nerve and carpal tunnel syndrome: an uncommon anatomical variation. Ann Ital Chir. 2017;88:95-96.

  PMID: 28447963 BACKGROUND

• Li ZM, Jordan DB. Carpal tunnel mechanics and its relevance to carpal tunnel syndrome. Hum Mov Sci. 2023 Feb;87:103044. doi: 10.1016/j.humov.2022.103044. Epub 2022 Nov 25.

  PMID: 36442295 BACKGROUND

• Talebi GA, Saadat P, Javadian Y, Taghipour M. Comparison of two manual therapy techniques in patients with carpal tunnel syndrome: A randomized clinical trial. Caspian J Intern Med. 2020;11(2):163-170. doi: 10.22088/cjim.11.2.163.

  PMID: 32509244 BACKGROUND

MeSH Terms

Conditions

Carpal Tunnel Syndrome; Pain

Condition Hierarchy (Ancestors)

Median Neuropathy; Mononeuropathies; Peripheral Nervous System Diseases; Neuromuscular Diseases; Nervous System Diseases; Nerve Compression Syndromes; Cumulative Trauma Disorders; Sprains and Strains; Wounds and Injuries; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• Ali Raza, MS-OMPT

  Riphah International University

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Imran Amjad, Phd

CONTACT

03324390125; Imran.amjad@riphah.edu.pk

Imran Amjad, Phd

CONTACT

051-5481826; Imran.amjad@riphah.edu.pk

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: November 12, 2024
• First Posted: November 13, 2024
• Study Start: January 4, 2024
• Primary Completion: January 7, 2025
• Study Completion: January 7, 2025
• Last Updated: November 13, 2024

Record last verified: 2024-11

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)