Prevalence of Hypomineralized Second Primary Molars and Its Association with Molar-Incisor Hypomineralization.

NCT06727539 | Not Yet Recruiting

• 1 other identifier: HSPM in Egyptian children
• Study Type: observational
• Target: 825
• Locations: 0 countries
• Sites: N/A

Brief Summary

The aim for thid study is to detect the prevalence of HSPM and the possible association between MIH and HSPM in a group of Egyptian children aged from 6-12 years. The study will also observe the possible etiological factors that might predispose hypomineralization of primary teeth. To our knowledge, there are no relevant studies that considered the prevalence of HSPM and its possible etiology in Egypt or its association with MIH. So, this study will address this knowledge gap. The possible relationship between HSPM and MIH is highly significant in pediatric dentistry, since the early diagnosis of HSPM as soon as second primary molars erupt makes it possible to initiate more intensive supervision and preventive measures, as these patients are otherwise prone to developing MIH in permanent teeth within a few years.

Conditions

Molar Incisor Hypomineralisation; Molar Incisor Hypomineralization; Hypomineralization Molar Incisor; Hypomineralization of Enamel

Outcome Measures

Primary Outcomes (1)

• Prevalence of HSPM in a group of Egyptian children using EAPD scoring criteria

  Prevalence of Hypomineralized Second Primary Molars in a group of Egyptian children using EAPD (European Academy of Pediatric Dentistry) scoring criteria

  Baseline

Secondary Outcomes (1)

• Correlation of HSPM with MIH

  Baseline

Eligibility Criteria

• Age: 7 Years - 12 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)
• Sampling Method: Non-Probability Sample

Study Population

The study will be done on pediatric patients with the age between 6-12 years old, attending outpatient clinic in the Department of Pediatric Dentistry and Public Health, Cairo university.

You may qualify if:

• Both genders will be included
• Children and adolescents with age group from 6-12 years
• Participants who agreed to sign rhe informed consent

You may not qualify if:

• Patients having enamel defects like fluorosis, amelogenesis imperfecta and dentinogenesis imperfecta
• Special health care needs
• Non-Egyptian children

Sponsors & Collaborators

• Cairo University: lead

Related Publications (3)

• Marcianes M, Garcia-Camba P, Albaladejo A, Varela Morales M. Predictive Value of Hypomineralization of Second Primary Molars for Molar Incisor Hypomineralization and Other Relationships between Both Developmental Defects of Dental Enamel. J Clin Med. 2023 Aug 25;12(17):5533. doi: 10.3390/jcm12175533.

  PMID: 37685598 BACKGROUND

• Estivals J, Fahd C, Baillet J, Rouas P, Manton DJ, Garot E. The prevalence and characteristics of and the association between MIH and HSPM in South-Western France. Int J Paediatr Dent. 2023 May;33(3):298-304. doi: 10.1111/ipd.13040. Epub 2022 Dec 27.

  PMID: 36511101 BACKGROUND

• Bekes K, Steffen R, Kramer N. Update of the molar incisor hypomineralization: Wurzburg concept. Eur Arch Paediatr Dent. 2023 Dec;24(6):807-813. doi: 10.1007/s40368-023-00848-5. Epub 2023 Oct 19.

  PMID: 37856065 BACKGROUND

MeSH Terms

Conditions

Molar Hypomineralization; Dental Enamel Hypomineralization

Condition Hierarchy (Ancestors)

Developmental Defects of Enamel; Tooth Abnormalities; Stomatognathic System Abnormalities; Stomatognathic Diseases; Tooth Diseases; Congenital Abnormalities; Congenital, Hereditary, and Neonatal Diseases and Abnormalities

Central Study Contacts

Nada ElSaeid

CONTACT

+201275907807; nada.elsaeid@dentistry.cu.edu.eg

Shaimaa Sabry, Dr.

CONTACT

+201006495926

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Main investigator

Study Record Dates

• First Submitted: December 9, 2024
• First Posted: December 11, 2024
• Study Start: January 1, 2025
• Primary Completion: January 1, 2026
• Study Completion: February 1, 2026
• Last Updated: December 16, 2024

Record last verified: 2024-12

Data Sharing

• IPD Sharing: Will not share