Hypo-mineralization of Primary and Permanent Teeth in a Group of Children With Stunted Growth.A Cross Sectional Study.

NCT04774653 | Unknown

• 1 other identifier: 00022021
• Study Type: observational
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

The second primary molar (SPM) development start at the same time as development of the first permanent molars (FPM) and permanent incisors so any systemic disturbance - causing stunted growth -occur , will result in hypo-mineralization of SPM as well as FPM and permanent incisors (Butler 1967, Weerheijm and Mejàre 2003). The literature shows no previous studies that discuss the association between hypo- mineralized second primary molar (HSPM), MIH and the stunted growth in children. aim: Estimate Prevalence of HSPM and MIH in stunted children.Evaluate the association between HSPM, MIH and the stunted growth in a group of Egyptian children. • The diagnostic criteria for MIH established based on the European Academy of Pediatric Dentistry criteria (Weerheijm and Mejàre 2003) while diagnostic criteria for HSPM was established by (Elfrink et al. 2008).

Conditions

Short Stature; Hypomineralization Molar Incisor; Hypomineralization of Enamel

Keywords

MIH; HSPM; Stunded children; Prevalence

Outcome Measures

Primary Outcomes (1)

• Prevalence of HSPM in stunted children

  Clinical examination (Weerheijm \& Mejàre, 2003) Length /Height for age WHO growth charts (WHO, Length/Height for age Boys and Girls Available., www.who.int/childgrowth (2017).

  6 Months from April to October 2021

Secondary Outcomes (1)

• Prevalence of MIH in stunted children

  6 Months ( from April to October 2021)

Other Outcomes (1)

• Association of MIH &HSPM with short stature

  6 Months ( from April to October 2021)

Study Arms (3)

MIH Group in short stature from 6-8 years old

Molar Incisor Hypomineralization in stunted children aged from 6-8 years

Other: No intervention

HSPM Group in short stature from 5-8 years old

Hypomineralization of Second Primary Molars in stunted children aged from 5-8 years

Other: No intervention

Both MIH &HSPM Group in stunted (from 5-8) years old

When both primary molars and permanent teeth( First permanent molars \& permanent incisors) are hypo-mineralized in children with short stature with age range from 5-8 years old

Other: No intervention

Interventions

No intervention OTHER

Associations and prevalence will be calculated

Both MIH &HSPM Group in stunted (from 5-8) years old; HSPM Group in short stature from 5-8 years old; MIH Group in short stature from 6-8 years old

Eligibility Criteria

• Age: 5 Years - 8 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)
• Sampling Method: Probability Sample

Study Population

Egyptian children aged from 5 to 8 years with short stature attending to Outpatient Clinic of Pediatric Dentistry Department, Faculty of Dentistry, Cairo University.

You may qualify if:

• Children aged from 5 to 8 years.
• Both genders.
• Stunted growth (Stunting: when the height for age is less than the mean by two standard deviations of the WHO Child Standards for growth or less than the 5th centile for age)

You may not qualify if:

• Children with extracted primary second molars and permanent incisors and molars.
• Children with history of dental trauma.
• Children with orthodontic bands or dental appliances.

Sponsors & Collaborators

• Cairo University: lead

Study Sites (1)

Department of Pediatric Dentistry, Faculty of Dentistry, Cairo University

Cairo, 0022, Egypt

RECRUITING

MeSH Terms

Conditions

Dwarfism; Molar Hypomineralization; Dental Enamel Hypomineralization

Condition Hierarchy (Ancestors)

Bone Diseases, Developmental; Bone Diseases; Musculoskeletal Diseases; Genetic Diseases, Inborn; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Endocrine System Diseases; Developmental Defects of Enamel; Tooth Abnormalities; Stomatognathic System Abnormalities; Stomatognathic Diseases; Tooth Diseases; Congenital Abnormalities

Study Officials

• Rania Nasr, Assoc. Prof.

  Department of Pediatric Dentistry and Dental Public Health, Faculty of Dentistry, Cairo University

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Rania Nasr, Assoc. Prof.

CONTACT

0020/ 01005037367; nasrania05@yahoo.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor Dr. Rania Nasr

Study Record Dates

• First Submitted: February 19, 2021
• First Posted: March 1, 2021
• Study Start: April 1, 2021
• Primary Completion: October 1, 2021
• Study Completion: December 1, 2021
• Last Updated: March 1, 2021

Record last verified: 2021-02

Locations

EG (1)