Prevalence of Hypomineralized Second Primary Molars In A Group of Egyptian Children

NCT06736535 | Not Yet Recruiting

• 1 other identifier: HPC in Egyptian Children
• Study Type: observational
• Target: 825
• Locations: 0 countries
• Sites: N/A

Brief Summary

Aim of the study: This study aims to detect the prevalence of hypomineralized second primary molars and its association with hypomineralized primary canines in a group of Egyptian children. Furthermore, it also addresses the possible etiological factors that might predispose hypomineralization of deciduous teeth. Rationale: This study tends to fill the knowledge gap about the prevalence of hypomineralized second primary molars as well as its association with hypomineralized primary canines in a group of Egyptian children. In addition to identifying the possible predisposing etiological factors.

Conditions

Hypomineralization of Enamel

Outcome Measures

Primary Outcomes (2)

• Prevalence of HPC in Egyptian Children

  Baseline

• Prevalence of HSPM in Egyptian Children

  Baseline

Eligibility Criteria

• Age: 4 Years - 9 Years
• Sex: all
• Age Groups: Child (0-17)
• Sampling Method: Non-Probability Sample

Study Population

Children attending Outpatient clinics of Cairo University will be recruited in the study.

You may qualify if:

• Children aged 4-9 years.
• Cooperative patients.
• Medically Free children.
• Both Genders; females and males will be included.

You may not qualify if:

• Non-Egyptian nationality.
• Special Health Care Needs Patients.
• Other developmental enamel defects (Non-MIH/HSPM); Amelogenesis Imperfecta, dental fluorosis and hypoplasia.
• Other medical syndromes.

Sponsors & Collaborators

• Cairo University: lead

Related Publications (5)

• Bekes K, Steffen R, Kramer N. Hypomineralised second primary molars: the Wurzburg concept. Eur Arch Paediatr Dent. 2024 Aug;25(4):597-602. doi: 10.1007/s40368-024-00913-7. Epub 2024 May 28.

  PMID: 38805129 BACKGROUND

• da Silva Figueiredo Se MJ, Ribeiro APD, Dos Santos-Pinto LAM, de Cassia Loiola Cordeiro R, Cabral RN, Leal SC. Are Hypomineralized Primary Molars and Canines Associated with Molar-Incisor Hypomineralization? Pediatr Dent. 2017 Nov 1;39(7):445-449.

  PMID: 29335050 BACKGROUND

• Elfrink ME, Ghanim A, Manton DJ, Weerheijm KL. Standardised studies on Molar Incisor Hypomineralisation (MIH) and Hypomineralised Second Primary Molars (HSPM): a need. Eur Arch Paediatr Dent. 2015 Jun;16(3):247-55. doi: 10.1007/s40368-015-0179-7. Epub 2015 Apr 18.

  PMID: 25894247 BACKGROUND

• Borrego-Marti N, Peris-Corominas R, Maura-Solivellas I, Ferres-Padro E, Ferres-Amat E. Hypomineralisation of second primary molars and primary canines: Prevalence and description of lesions in a population of 153 patients visited at a hospital paediatric dentistry service. Eur J Paediatr Dent. 2021 Sep;22(3):237-242. doi: 10.23804/ejpd.2021.22.03.11.

  PMID: 34544254 BACKGROUND

• Lygidakis NA, Garot E, Somani C, Taylor GD, Rouas P, Wong FSL. Best clinical practice guidance for clinicians dealing with children presenting with molar-incisor-hypomineralisation (MIH): an updated European Academy of Paediatric Dentistry policy document. Eur Arch Paediatr Dent. 2022 Feb;23(1):3-21. doi: 10.1007/s40368-021-00668-5. Epub 2021 Oct 20.

  PMID: 34669177 BACKGROUND

MeSH Terms

Conditions

Dental Enamel Hypomineralization

Condition Hierarchy (Ancestors)

Developmental Defects of Enamel; Tooth Abnormalities; Stomatognathic System Abnormalities; Stomatognathic Diseases; Tooth Diseases; Congenital Abnormalities; Congenital, Hereditary, and Neonatal Diseases and Abnormalities

Central Study Contacts

Farida Khalid Noaman

CONTACT

01060511700; farida.noaman@dentistry.cu.edu.eg

Study Design

• Study Type: observational
• Observational Model: ECOLOGIC OR COMMUNITY
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Prevalence of Hypomineralized Second Primary Molars and Its Association with Hypomineralized Primary Canines In A Group of Egyptian Children

Study Record Dates

• First Submitted: December 12, 2024
• First Posted: December 16, 2024
• Study Start: January 1, 2025
• Primary Completion: January 1, 2026
• Study Completion: February 1, 2026
• Last Updated: December 16, 2024

Record last verified: 2024-12

Data Sharing

• IPD Sharing: Will not share