Prevalence And Severity Of Molar Incisor Hypomineralization Among A Group Of Children With Type I Diabetes Milletus.

NCT06342089 | Not Yet Recruiting

• 1 other identifier: NCT06342089
• Study Type: observational
• Target: 238
• Locations: 0 countries
• Sites: N/A

Brief Summary

• Determine the prevalence of molar incisor hypomineralization among a group of children with type I diabetes millutes, its severity and treatment need via clinical examination of children with type I diabetes millutes .
• Teeth will be cleaned gently using gauze and wet with saliva during examination. A disposable diagnostic set (mirror, probe) will be used for each patient where mirrors will be used for proper visualization especially for maxillary teeth.
• Blunt explorers will be used to aid in tactile sensation if needed, as during the differentiation between rough and smooth enamel edges and/or during the inspection of the caries extent if it exists. No diagnostic radiographs will be taken.
• The severity and treatment needs of each case with MIH will be recorded in patient's chart.
• The results of the study will be regularly monitored by the supervisors who will have full access to these results.

Conditions

Molar Incisor Hypomineralization

Keywords

Molar Incisor Hypomineralization (MIH); Type I diabetes milletus(TIDM)

Outcome Measures

Primary Outcomes (1)

• prevalence of molar incisor Hypomineralization among among a group of children with type I diabetes milletus.

  The prevalence will be measured according to the diagnostic criteria of molar incisor Hypomineralization established by European Academy of Pediatric Dentistry. Measuring unit: percentage

  one year

Secondary Outcomes (2)

• Severity of molar incisor Hypomineralization among among a group of children with type I diabetes milletus.

  one year

• Treatment need

  one year

Study Arms (1)

children with type I diabetes milletus

•Patient aged 8 to 14 years and diagnosed with type I diabetes milletus with erupted all 4 first permanent molars.

Other: Type I diabetes milletus

Interventions

Type I diabetes milletus OTHER

the exposure is type I diabetes milletus

children with type I diabetes milletus

Eligibility Criteria

• Age: 8 Years - 14 Years
• Sex: all
• Age Groups: Child (0-17)
• Sampling Method: Non-Probability Sample

Study Population

* This cross-sectional study will be carried out by recruiting a sample of participants previously diagnosed with types I diabetes milletus aged from( 8-14) accept to participate. * All permanent molars must be erupted as the diagnosis of molar incisor hypomineralization required at least one permanent molar involved . * The patient mustn't have any other medical conditions nor orthodontic appliance that may affect the enamel quality

You may qualify if:

• Patient aged 8 to 14 years and diagnosed with types I diabetes milletus.
• Eruption of all 4 first permanent molars.
• Acceptance to participate.

You may not qualify if:

• Presence of orthodontic appliance.
• Patient with any other type of enamel defect.
• Patients with any other systemic conditions rather than types I diabetes milletus that may affect tooth development.

Sponsors & Collaborators

• Cairo University: lead

Related Publications (5)

• Cingolani R, Stolz W, Ploog K. Electronic states and optical transitions in modulation-doped n-type GaxIn1-xAs/AlxIn1-xAs multiple quantum wells. Phys Rev B Condens Matter. 1989 Aug 15;40(5):2950-2955. doi: 10.1103/physrevb.40.2950. No abstract available.

  PMID: 9992226 BACKGROUND

• Ghanim A, Silva MJ, Elfrink MEC, Lygidakis NA, Marino RJ, Weerheijm KL, Manton DJ. Molar incisor hypomineralisation (MIH) training manual for clinical field surveys and practice. Eur Arch Paediatr Dent. 2017 Aug;18(4):225-242. doi: 10.1007/s40368-017-0293-9. Epub 2017 Jul 18.

  PMID: 28721667 BACKGROUND

• Lygidakis NA, Garot E, Somani C, Taylor GD, Rouas P, Wong FSL. Best clinical practice guidance for clinicians dealing with children presenting with molar-incisor-hypomineralisation (MIH): an updated European Academy of Paediatric Dentistry policy document. Eur Arch Paediatr Dent. 2022 Feb;23(1):3-21. doi: 10.1007/s40368-021-00668-5. Epub 2021 Oct 20.

  PMID: 34669177 BACKGROUND

• Steffen R, Kramer N, Bekes K. The Wurzburg MIH concept: the MIH treatment need index (MIH TNI) : A new index to assess and plan treatment in patients with molar incisior hypomineralisation (MIH). Eur Arch Paediatr Dent. 2017 Oct;18(5):355-361. doi: 10.1007/s40368-017-0301-0. Epub 2017 Sep 14.

  PMID: 28913739 BACKGROUND

• Mast P, Rodrigueztapia MT, Daeniker L, Krejci I. Understanding MIH: definition, epidemiology, differential diagnosis and new treatment guidelines. Eur J Paediatr Dent. 2013 Sep;14(3):204-8.

  PMID: 24295005 BACKGROUND

MeSH Terms

Conditions

Molar Hypomineralization

Condition Hierarchy (Ancestors)

Dental Enamel Hypomineralization; Developmental Defects of Enamel; Tooth Abnormalities; Stomatognathic System Abnormalities; Stomatognathic Diseases; Tooth Diseases; Congenital Abnormalities; Congenital, Hereditary, and Neonatal Diseases and Abnormalities

Central Study Contacts

mariam samir fahmy, masters

CONTACT

01226493173; mariam.auob@dentistry.cu.edu.eg

Study Design

• Study Type: observational
• Observational Model: ECOLOGIC OR COMMUNITY
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Resident doctor at the Department of Pediatric Dentistry

Study Record Dates

• First Submitted: March 26, 2024
• First Posted: April 2, 2024
• Study Start: September 1, 2024
• Primary Completion: November 1, 2024
• Study Completion: May 1, 2025
• Last Updated: July 16, 2024

Record last verified: 2024-07