NCT06701552

Brief Summary

We are conducting a study to understand how often MIH (Molar Incisor Hypomineralization) occurs and whether it is linked to a higher chance of dental cavities (caries). MIH is a condition where the enamel (the hard outer surface) of the first permanent molars and incisors (front teeth) doesn't develop properly, making these teeth more prone to damage and decay. We are looking at whether patients with MIH have more cavities in their teeth compared to patients without MIH. This study aims to help us learn more about the connection between MIH and dental health, so we can improve care and prevention strategies for kids at risk of cavities.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
266

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Nov 2024

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2024

Completed
19 days until next milestone

First Submitted

Initial submission to the registry

November 20, 2024

Completed
2 days until next milestone

First Posted

Study publicly available on registry

November 22, 2024

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2025

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 2025

Completed
Last Updated

November 22, 2024

Status Verified

November 1, 2024

Enrollment Period

2 months

First QC Date

November 20, 2024

Last Update Submit

November 20, 2024

Conditions

Keywords

MIH

Outcome Measures

Primary Outcomes (1)

  • prevalence of MIH

    Prevalence of MIH among patients will be described as a percentage

    one year

Study Arms (1)

A Group of 266 young adult Egyptian patients

Patients will be examined for prevalence of molar incisor hypomineraliztion and its correlation to caries incidence

Eligibility Criteria

Age18 Years - 30 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)
Sampling MethodProbability Sample
Study Population

Egyptian participants whose between 18 and 30 years old, both sexes will be included

You may qualify if:

  • patients whose age between 18 and 30 years old provide informed consent Egyptian patients from both sexes

You may not qualify if:

  • patients under or over this age group patients undergoing orthodontic treatment patients who refuse to participate

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Faculty of Dentistry, Cairo University

Cairo, Egypt

Location

Biospecimen

Retention: SAMPLES WITHOUT DNA

There is no sample to be retained as this is a cross sectional study aiming to know the prevalence of MIH among young adults and its correlation to caries prevalence

MeSH Terms

Conditions

Molar HypomineralizationDental Caries

Condition Hierarchy (Ancestors)

Dental Enamel HypomineralizationDevelopmental Defects of EnamelTooth AbnormalitiesStomatognathic System AbnormalitiesStomatognathic DiseasesTooth DiseasesCongenital AbnormalitiesCongenital, Hereditary, and Neonatal Diseases and AbnormalitiesTooth Demineralization

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
dentist

Study Record Dates

First Submitted

November 20, 2024

First Posted

November 22, 2024

Study Start

November 1, 2024

Primary Completion

January 1, 2025

Study Completion

February 1, 2025

Last Updated

November 22, 2024

Record last verified: 2024-11

Data Sharing

IPD Sharing
Will share

Locations