The Relationship Between Body Mass Index and Patient Outcomes in Low Flow Anaesthesia

NCT06636448 | Completed

• 1 other identifier: 2024-04
• Study Type: observational
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

This study was designed as a prospective observational study.

Conditions

Major Gynecological Cancer Surgery; Low Flow Anesthesia

Keywords

major gynecological cancer surgery; low flow aneshesia; cerebral oxygenation; hypoxia

Outcome Measures

Primary Outcomes (1)

• postoperative hospital stay

  The primary aim of this study was to evaluate the duration of postoperative hospital stay

  up to 10 days postoperative

Other Outcomes (1)

• Intraoperative cerebral oxygenation

  intraoperative process

Study Arms (1)

obese patients undergoing low-flow anaesthesia

Low-flow anaesthesia was performed in patients with a body mass index between 30-40

Procedure: the effect of body mass index during low-flow anesthesia

Interventions

the effect of body mass index during low-flow anesthesia PROCEDURE

The investigator planned to evaluate the effect of body mass index on patient outcomes during low-flow anesthesia in patients undergoing gynecologic cancer surgery.

obese patients undergoing low-flow anaesthesia

Eligibility Criteria

• Age: 18 Years+
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

A total of 40 patients were planned for this study

You may qualify if:

• Patients with ASA II-III
• \>18 years
• Patients undergoing major open surgery for endometrium, cervix or ovarian ca in gynaecological oncology clinic

You may not qualify if:

• Patients who refused to participate in the study
• Cerebrovascular disease
• Those with severe pulmonary disease
• Those with serious cardiovascular disease

Sponsors & Collaborators

• Bakirkoy Dr. Sadi Konuk Research and Training Hospital: lead

Study Sites (1)

Duygu

Istanbul, Turkey (Türkiye)

Location

Related Publications (3)

• Mychaskiw G 2nd. Low and minimal flow anesthesia: Angels dancing on the point of a needle. J Anaesthesiol Clin Pharmacol. 2012 Oct;28(4):423-5. doi: 10.4103/0970-9185.101883. No abstract available.

  PMID: 23225917 BACKGROUND

• Oterkus M, Donmez I, Nadir AH, Rencuzogullari I, Karabag Y, Binnetoglu K. The effect of low flow anesthesia on hemodynamic and peripheral oxygenation parameters in obesity surgery. Saudi Med J. 2021 Mar;42(3):264-269. doi: 10.15537/smj.2021.42.3.20200575.

  PMID: 33632904 BACKGROUND

• Akbas S, Ozkan AS. Comparison of effects of low-flow and normal-flow anesthesia on cerebral oxygenation and bispectral index in morbidly obese patients undergoing laparoscopic sleeve gastrectomy: a prospective, randomized clinical trial. Wideochir Inne Tech Maloinwazyjne. 2019 Jan;14(1):19-26. doi: 10.5114/wiitm.2018.77265. Epub 2018 Jul 24.

  PMID: 30766625 BACKGROUND

MeSH Terms

Conditions

Hypoxia

Condition Hierarchy (Ancestors)

Signs and Symptoms, Respiratory; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 1 Day
• Sponsor Type: OTHER GOV
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal investigator

Study Record Dates

• First Submitted: September 27, 2024
• First Posted: October 10, 2024
• Study Start: November 1, 2024
• Primary Completion: February 1, 2025
• Study Completion: March 1, 2025
• Last Updated: August 13, 2025

Record last verified: 2024-09

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)