Caffeine Supplementation on Movement Patterns and Reactive Agility in Rugby Sevens Matches

NCT06612463 | Completed Early Phase 1

• 2 other identifiers: 111-03MOST 111-2410-H-028-002-MY3
• Study Type: interventional
• Target: 8
• Locations: 1 country
• Sites: 1

Brief Summary

Caffeine is widely used by rugby players for its performance-enhancing effects. The main questions it aims to answer are: (1) the impact of caffeine supplementation on various performance metrics, including distance covered at different speeds, acceleration, deceleration, collisions, and repeated high-intensity efforts; and (2) reactive agility, across four matches over two consecutive days in collegiate male rugby sevens players.A position-matched, double-blind, randomized crossover design was employed, with six male collegiate rugby players (mean height: 1.78 ± 0.09 m, mean weight: 81.3 ± 9.2 kg) participating in two trials. Each trial consisted of a two-day tournament, with two matches per day. Movement was monitored using global positioning system units.

Conditions

Exercise

Keywords

caffeine; rugby sevens; global positioning system

Outcome Measures

Primary Outcomes (5)

• Total Distance and Distance Covered in Speed Zones

  This variable was measured with wearable global positioning system device during rugby sevens matches. Speed is divided into six zones: standing and walking (0-6 km/h), jogging (6-12 km/h), cruising (12-14 km/h), striding (14-18 km/h), high-intensity running (18-20 km/h), and sprinting (\> 20 km/h). The distance covered in each speed zone and the total distance covered were recorded.

  Each trial contained 2 days, with 2 matches on each day. Each participant completed 2 trials

• Acceleration and Deceleration

  This variable was measured with wearable global positioning system device during rugby sevens matches. For an activity to be included in the analysis, the movement speed must exceed 5 km/h, and the acceleration must be greater than 2 m/s² or the deceleration must be less than -2 m/s², sustained for more than 0.9 s. If the interval between two movements is less than 1 s, the subsequent movement will be combined with the previous one for analysis. The frequency and distance covered during these acceleration and deceleration phases were recorded.

  Each trial contained 2 days, with 2 matches on each day. Each participant completed 2 trials

• collision

  This variable was measured with wearable global positioning system device during rugby sevens matches. Collision is defined as the number of times a participant accumulates 0.5 s standing after body contact resulting in a fall. Specific collision events include rucks, tackles, and instances where a player falls after contact

  Each trial contained 2 days, with 2 matches on each day. Each participant completed 2 trials

• Repeated High-Intensity Effort

  This variable was measured with wearable global positioning system device during rugby sevens matches. A repeated high-intensity effort is defined as the completion of three or more high-intensity actions in succession, with rest periods of no more than 21 s between each action. The criteria for high-intensity actions include a movement speed of at least 14 km/h, an acceleration of at least 2 m/s², and a deceleration of at least -2 m/s²

  Each trial contained 2 days, with 2 matches on each day. Each participant completed 2 trials

• Reactive Agility

  The participants sprinted with the ball, passing through a light gate, after which an indicator light immediately displayed a left or right direction. The participants had to respond by changing direction according to the indicator and continue moving until they passed the second light gate positioned 1.5 m away from the indicator. The fastest time from two attempts was used for analysis.

  Each trial contained 2 days, with 2 matches on each day. Reactive agility was measured before each match. Each participant completed 2 trials

Study Arms (2)

Caffeine

EXPERIMENTAL

In the caffeine trial, participants ingested a capsule containing 3 mg/kg caffeine (Wako Pure Chemical Industries, Ltd., Osaka, Japan) 60 min prior to the match.

Dietary Supplement: Caffeine 6mg/kg

Placebo

PLACEBO COMPARATOR

In the placebo trial, participants ingested a capsule containing starch (Chung-Yu Biotech Co LTD, Taichung, Taiwan) at the same time point.

Dietary Supplement: Placebo

Interventions

Caffeine 6mg/kg DIETARY_SUPPLEMENT

In the caffeine trial, participants ingested a capsule containing 3 mg/kg caffeine 60 min prior to each rugby sevens match. There was 2 matches per day. So the total dosage is 6 mg/kg/ day

Caffeine

Placebo DIETARY_SUPPLEMENT

In the placebo trial, participants ingested a capsule containing starch 60 min before each rugby sevens match. There were 2 matches per day

Placebo

Eligibility Criteria

• Age: 18 Years+
• Sex: male
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Have undergone regular rugby training for at least three years
• Member of a Division I university rugby team

You may not qualify if:

• Musculoskeletal injury within one month prior to the study
• Presence of major cardiovascular diseases
• Presence of major metabolic diseases

Sponsors & Collaborators

• National Taiwan Sport University: lead

Study Sites (1)

National Taiwan University of Sport

Taichung, 404, Taiwan

Location

Related Publications (1)

• Del Coso J, Portillo J, Munoz G, Abian-Vicen J, Gonzalez-Millan C, Munoz-Guerra J. Caffeine-containing energy drink improves sprint performance during an international rugby sevens competition. Amino Acids. 2013 Jun;44(6):1511-9. doi: 10.1007/s00726-013-1473-5. Epub 2013 Mar 5.

  PMID: 23462927 RESULT

MeSH Terms

Conditions

Motor Activity

Interventions

Caffeine

Condition Hierarchy (Ancestors)

Behavior

Intervention Hierarchy (Ancestors)

Xanthines; Alkaloids; Heterocyclic Compounds; Purinones; Purines; Heterocyclic Compounds, 2-Ring; Heterocyclic Compounds, Fused-Ring

Study Officials

• Chen-Kang Chang, PhD

  National Taiwan University of Sport

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: early phase 1
• Allocation: NON RANDOMIZED
• Masking: TRIPLE
• Who Masked: PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
• Masking Details: The capsules used in both trials were identical in appearance. The caffeine and placebo supplements were prepared by a laboratory technician who was independent of the study.
• Purpose: BASIC SCIENCE
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Model Details: 2 types of Intervention: caffeine or placebo. Arm 1: Caffeine trial: Participants ingested a capsule containing 3 mg/kg caffeine (Wako Pure Chemical Industries, Ltd., Osaka, Japan) 60 min prior to the match. Arm 2: Placebo trial: Participants ingested a capsule containing starch (Chung-Yu Biotech Co LTD, Taichung, Taiwan) at the same time point. The capsules used in both trials were identical in appearance. The caffeine and placebo supplements were prepared by a laboratory technician who was independent of the study.

Study Record Dates

• First Submitted: September 21, 2024
• First Posted: September 25, 2024
• Study Start: August 1, 2023
• Primary Completion: October 30, 2023
• Study Completion: April 30, 2024
• Last Updated: October 1, 2024

Record last verified: 2024-09

Data Sharing

• IPD Sharing: Will not share

Locations

TW (1)