Comprehensive Dementia Management : From Translational Medicine to Innovative Care

NCT06214962 | Recruiting

• 1 other identifier: KMUHIRB-SV(I)-20220016
• Study Type: observational
• Target: 652
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this stage is to conduct analysis and discussion through expert meetings (consultation) based on the current data of the elderly in each dementia base and Rizhao Center, as well as the weekly courses and activities of the service site (base, Rizhao), and make recommendations.

Conditions

Exercise

Outcome Measures

Primary Outcomes (5)

• basic information

  Including gender, age, height, weight, marital status, education level, Gender: This pertains to the participant's biological gender and may be identified as either male or female. Age: Represents the participant's age, typically measured in years. Height: The participant's height, typically measured in centimeters or inches. Weight: The participant's weight, typically measured in kilograms or pounds. Marital Status: Describes the participant's current marital status, such as married, unmarried, divorced, etc. Educational Level: This indicates the participant's level of education, including degrees or other educational qualifications. Medical Conditions: Describes the participant's health condition, which may encompass past medical history, current illnesses, or chronic conditions.

  Two weeks before intervention

• cognitive function assessment

  (SPMSQ - Short Portable Mental Status Questionnaire): Description: SPMSQ, a concise cognitive screening tool, assesses memory and cognitive function via questions on orientation, memory, and mathematical abilities. (Mini-Mental State Examination; MMSE): Description: MMSE, widely used for cognitive function assessment, covers domains like orientation, registration, attention, calculation, recall, language, and visuospatial skills. (Cognitive Abilities Screening Instrument; CASI): Description: CASI, a comprehensive tool, assesses attention, concentration, orientation, short-term memory, language, and visual construction. Scoring: Scores can range from 0 to 100, with higher scores indicating better cognitive function. Specific cutoff scores may be used to identify different levels of cognitive impairment.

  Two weeks before intervention

• Psychiatric and behavioral symptoms

  Use NPI or other mental behavioral scales that are more suitable for Rizhao elders NPI (Neuropsychiatric Inventory): Description: The NPI is a tool designed to assess neuropsychiatric behaviors, particularly in the elderly. It covers various domains such as hallucinations, anxiety, depression, insomnia, etc., providing insights into the assessed individual's behavioral symptoms. Scoring: Each domain has corresponding scores, and a total score helps assess the severity of neuropsychiatric symptoms.

  Two weeks before intervention

• daily life functions

  Measured by Pap scale and IADL. Barthel Index: Description: The Barthel Index assesses an individual's activities of daily living and self-care abilities, especially in rehabilitation and residential care settings. It includes basic activities like eating, bathing, dressing, toileting, etc. Scoring: Each activity is assigned specific scores, and the total score is used to evaluate the overall self-care abilities of the individual. Higher scores indicate better daily living skills. IADL (Instrumental Activities of Daily Living): Description: IADL is used to assess more complex daily living skills, such as shopping, cooking, using the phone, handling finances, etc. These skills reflect an individual's level of independence in social and home settings. Scoring: IADL scores are used to evaluate the individual's capabilities in these more complex activities. Higher scores indicate stronger independent abilities.

  Two weeks before intervention

• body movement function

  Hand Grip Strength: Description: Hand grip strength is a test to assess an individual's hand muscle strength, usually measured using a hand dynamometer. Single Leg Stand: Description: Single leg stand is a test to assess balance and stability, typically requiring the individual to stand on one leg for a certain duration to test their control of the center of gravity. Five Times Sit-to-Stand: Description: This test assesses lower limb strength and the ability to stand up, requiring the individual to stand up and sit down five times to test muscle strength and coordination. Timed Up and Go: Description: Timed Up and Go is a test assessing dynamic balance and walking ability. It requires the individual to stand up from a chair, walk a distance, and then return to sit down. Walking Speed: Description: Walking speed tests assess the individual's speed during walking, serving as an important indicator of daily activity ability and quality of life.

  Two weeks before intervention

Interventions

(multiple training modalities, MTM) BEHAVIORAL

1. Invite experts to discuss the course content of each unit of MTM, and then invite teachers to take pictures , and combine them into one course for the benefit of the elderly in the institution. 2. Select 3 units to try out in the dementia base, and make corrections based on the feedback of the elders and the base staff. 3. Continue to complete other units based on the experience of the first 3 units. (2) In the Rizhao part, experts are mainly used to develop various course modules suitable for the elderly with dementia in Rizhao, and each module unit is tested on the elderly with dementia and then revised The planning task is mainly to establish a solution strategy. The method is to set up an "activity course module planning or design group" to develop various course modules suitable for Rizhao demented elders.

Eligibility Criteria

• Age: 50 Years - 99 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The objects of data collection are the elders, their families, and caregivers in the bases and Rizhao. The research team only makes suggestions on the courses in the institutions that are willing to participate, and makes suggestions on the implementation of course activities with the personnel who originally booked the courses. It is not the project that sends people to the base or directly leads the activities in Rizhao. The researchers of this project are Facilitator of course activities and data collector or evaluator of effectiveness items.

You may qualify if:

• Recruit the elders (and their family members) in community bases and Rizhao centers, caregivers of bases and Rizhao centers.

You may not qualify if:

• Because the plan hopes to conduct an extensive inventory/detection of the dementia and disability status of the elderly in the dementia stronghold and Rizhao Center, unless the subjects do not want to To join the research, there are no conditions for case scheduling in this plan

Sponsors & Collaborators

• Kaohsiung Medical University Chung-Ho Memorial Hospital: lead
• National Health Research Institutes, Taiwan: collaborator

Study Sites (1)

Lih-Jiun Liaw

Kaohsiung City, 807057, Taiwan

RECRUITING

MeSH Terms

Conditions

Motor Activity

Interventions

myotubularin

Condition Hierarchy (Ancestors)

Behavior

Study Officials

• Li-Jiun Liaw

  Kaohsiung Medical University Department of Physical Therapy Associate Professor

  STUDY DIRECTOR

Central Study Contacts

Li-Jiun Liaw

CONTACT

+88673121101; lijili@kmu.edu.tw

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: March 13, 2023
• First Posted: January 22, 2024
• Study Start: June 10, 2022
• Primary Completion: February 1, 2026
• Study Completion: February 28, 2026
• Last Updated: March 21, 2024

Record last verified: 2023-03

Data Sharing

• IPD Sharing: Will not share

Locations

TW (1)