Comparison of Two Different Intensity Exercises on Young Women With Obesity

NCT06610955 | Recruiting

• 1 other identifier: AEU-FTR-EK-01
• Study Type: interventional
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

Obesity is one of the most common preventable public health problems. Diet regulation and exercise practices are the most commonly used methods in reducing fat tissue. There are various exercise methods applied in the weight loss process and the effects of different types of exercise modalities on body fat rate and metabolic status.The aim of our study is to determine the effects of high intensity interval exercise and moderate intensity continuous exercise on serum , omentin, leptin and adiponectin levels, anthropometric measurements used in obesity follow up, body fat percentage and their effects on the quality of sleep and life of women with obesity.

Conditions

Obesity; Exercise Training

Keywords

Obesity; Exercise Training; Adipokines

Outcome Measures

Primary Outcomes (1)

• Serum adipokine levels

  This study aimed to investigate the effects of high intensity interval exercise and moderate intensity continuous exercise on serum adiponectin, leptin and omentin levels in young women with obesity.

  8 weeks

Secondary Outcomes (4)

• Anthropometric measurement

  8 weeks

• Percentage of body fat

  8 weeks

• The impact of weight on quality of life

  8 weeks

• Quality of sleep

  8 weeks

Study Arms (2)

High intensity interval training exercise group

ACTIVE COMPARATOR

After a 10 minutes warm up exercise, participants will exercise with a bicycle ergometry device at 80% of their maximum heart rate for 4 minutes, and the active recovery period will be 3 minutes (4x4 minutes). During the recovery period, the participant will exercise with the Ergoline bicycle ergometry system for 4 sets at 60% of their maximum heart rate for 3 minutes. A total of 45 minutes exercise session will be completed with a 10 minutes cool down exercise. Exercise will be done 5 days a week for a total of 8 weeks. In the first 4 weeks, exercise will be done at 80% intensity, and in the following weeks, the exercise intensity will be increased by 5% each week, respectively, to 85%, 90%, 95%, and 100% in the last week.

Other: High intensity interval training

Moderate intensity continuous exercise group

ACTIVE COMPARATOR

Following a 10 minutes warm up exercise, participants will exercise continuously for 30 minutes at 65% of their maximum heart rate with the Ergoline bicycle ergometry system. A 5 minutes cool down exercise will end the 45 minutes exercise session. The exercise duration is 5 days a week for a total of 8 weeks.

Other: Moderate intensity continuous training

Interventions

High intensity interval training OTHER

After a 10 minutes warm up exercise, participants will exercise with a bicycle ergometry device at 80% of their maximum heart rate for 4 minutes, and the active recovery period will be 3 minutes (4x4 minutes). During the recovery period, the participant will exercise with the Ergoline bicycle ergometry system for 4 sets at 60% of their maximum heart rate for 3 minutes. A total of 45 minutes exercise session will be completed with a 10 minutes cool down exercise. Exercise will be done 5 days a week for a total of 8 weeks. In the first 4 weeks, exercise will be done at 80% intensity, and in the following weeks, the exercise intensity will be increased by 5% each week, respectively, to 85%, 90%, 95%, and 100% in the last week.

High intensity interval training exercise group

Moderate intensity continuous training OTHER

Following a 10 minutes warm up exercise, participants will exercise continuously for 30 minutes at 65% of their maximum heart rate with the Ergoline bicycle ergometry system. A 5 minutes cool down exercise will end the 45 minutes exercise session. The exercise duration is 5 days a week for a total of 8 weeks.

Moderate intensity continuous exercise group

Eligibility Criteria

• Age: 18 Years - 45 Years
• Sex: female
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Female between the age of 18-45
• BMI 30-40 kg/m²
• Primary obesity

You may not qualify if:

• Patients with cardiac, pulmonary, endocrinological, rheumatological diseases
• Pregnancy and breastfeeding
• Using antipsychotics, antidepressants (lithium, tricyclic antidepressants, mono amino oxidase inhibitors), anticonvulsants, antihistamines, glucocorticoids, antidiabetics (sulfonylureas, insulins, glitazones) sex hormones
• Using oral contraceptives
• History of bariatric surgery
• Patients using obesity medication in the last 6 months, complying with a regular diet and exercise program
• Presence of orthopedic or neurological problems that difficulty of participate aerobic exercise training

Sponsors & Collaborators

• Ahi Evran University Education and Research Hospital: lead
• Kirsehir Ahi Evran Universitesi: collaborator

Study Sites (1)

Kırşehir Ahi Evran Üniversitesi

Kırşehir, 40100, Turkey (Türkiye)

RECRUITING

Related Links

• Effect of High-Intensity Interval Training on Plasma Omentin-1 Concentration in Overweight/Obese and Normal-Weight Youth

MeSH Terms

Conditions

Obesity

Interventions

High-Intensity Interval Training

Condition Hierarchy (Ancestors)

Overweight; Overnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases; Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Physical Conditioning, Human; Exercise; Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Officials

• Figen Tuncay, Professor

  Ahi Evran Univeristy

  PRINCIPAL INVESTIGATOR

• Elif Kapaklı, RA

  Kirsehir Ahi Evran Universitesi

  STUDY CHAIR

• Gamze Turna Saltoğlu, Ass. Prof.

  Kirsehir Ahi Evran Universitesi

  STUDY CHAIR

• Başak Çiğdem Karaçay, Assoc. Prof.

  Kirsehir Ahi Evran Universitesi

  STUDY CHAIR

• Nazife Kapan, Ass. Prof.

  Kirsehir Ahi Evran Universitesi

  STUDY CHAIR

• Başak Kavalcı Kol, Ass. Prof.

  Kirsehir Ahi Evran Universitesi

  STUDY CHAIR

• Merve Fırat, Ass. Prof.

  Kirsehir Ahi Evran Universitesi

  STUDY CHAIR

Central Study Contacts

Figen Tuncay, Professor

CONTACT

5353046401; figentuncay3206@hotmail.com

Elif Kapaklı, RA

CONTACT

5432139966; elifkapakli@gmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: INVESTIGATOR, OUTCOMES ASSESSOR
• Masking Details: Outcome assessments will be performed by a doctor who will be blinded to exercise group allocation
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Model Details: Two groups without control group

Study Record Dates

• First Submitted: September 15, 2024
• First Posted: September 24, 2024
• Study Start: October 18, 2024
• Primary Completion: July 1, 2025
• Study Completion: July 1, 2025
• Last Updated: February 5, 2025

Record last verified: 2025-02

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)