Effect of PECS II, Parasternal and Serratus Plane Blocks on Postoperative Pain in MIDCAB Surgery

NCT06584981 | Completed DMC

• 1 other identifier: HisarH
• Study Type: interventional
• Target: 88
• Locations: 1 country
• Sites: 1

Brief Summary

AIM: It was aimed to evaluate the effectiveness of pectoral nerve block (PECS II), parasternal and serratus plane blocks in postoperative analgesia in minimally invasive cardiac surgery (MIDCAB). INTRODUCTION: The frequency of minimally invasive cardiac surgery has increased in recent years. With this method, Coronary artery bypass graft (CABG) operations can be performed without sternotomy. It is a beneficial method for early postoperative mobilization, early recovery and better aesthetic appearance. Since there is a surgical intervention between the ribs, pain control is important in these patients. METHOD: In the preoperative evaluation of patients planned for CABG, PECS II, parasternal and serratus plane blocks are routinely recommended for postoperative pain control. Consent for the procedure is obtained from patients who accept this procedure. After induction and before the surgical incision, these block applications are performed under sterile conditions under the guidance of ultrasonography. Standard intravenous analgesic agents are applied to our patients who do not accept block applications. The hospital core system files of our patients who underwent cardiac surgery with minimally invasive intervention in our hospital between January 1, 2021 and December 31, 2021 will be scanned retrospectively. Patients with and without block application will be divided into two groups. From our patients' files; Demographic data, extubation time, drain site and incision site pain at the 1st, 2nd, 4th, 12th, 24th, 48th and 72nd hours after extubation will be noted. In addition, it will be noted whether there is a need for additional rescue analgesia in cases where block is performed. The data obtained will be evaluated statistically and the results will be published in national or international scientific journals.

Conditions

Pain, Postoperative; Coronary Artery Disease

Outcome Measures

Primary Outcomes (1)

• Analgesic efficiency

  drain site and incision site pain at the 1st, 2nd, 4th, 12th, 24th, 48th and 72nd hours after extubation will be noted

Study Arms (2)

Patients who underwent block

ACTIVE COMPARATOR

Patients who underwent pectoral nerve block (PECS II), parasternal and serratus plane blocks will be included in this group.

Procedure: pectoral nerve block (PECS II), parasternal and serratus plane blocks

Patients who did not receive block

OTHER

Patients who were not given a block and received standard intravenous analgesics will be included in this group.

Other: analgesic

Interventions

pectoral nerve block (PECS II), parasternal and serratus plane blocks PROCEDURE

These block applications are performed under sterile conditions under the guidance of ultrasonography

Patients who underwent block

analgesic OTHER

Analgesia needs of patients who do not receive blockade are met with intravenous drugs.

Patients who did not receive block

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Adult patients aged 18 and over
• Patients who underwent MIDCAB surgery

You may not qualify if:

• Patients under 18 years of age
• Patients who did not undergo MIDCAB surgery

Sponsors & Collaborators

• Hisar Intercontinental Hospital: lead

Study Sites (1)

Hisar Intercontinental Hospital

Istanbul, Turkey (Türkiye)

Location

Related Publications (3)

• Gautam S, Pande S, Agarwal A, Agarwal SK, Rastogi A, Shamshery C, Singh A. Evaluation of Serratus Anterior Plane Block for Pain Relief in Patients Undergoing MIDCAB Surgery. Innovations (Phila). 2020 Mar/Apr;15(2):148-154. doi: 10.1177/1556984520908962.

  PMID: 32352903 RESULT

• Xin L, Wang L, Feng Y. Ultrasound-guided erector spinae plane block for postoperative analgesia in patients undergoing minimally invasive direct coronary artery bypass surgery: a double-blinded randomized controlled trial. Can J Anaesth. 2024 Jun;71(6):784-792. doi: 10.1007/s12630-023-02637-6. Epub 2023 Nov 21.

  PMID: 37989939 RESULT

• Moll V, Ward CT, Jabaley CS, O'Reilly-Shah VN, Boorman DW, McKenzie-Brown AM, Halkos ME, Prabhakar A, Pyronneau LR, Schmidt PC. Erector Spinae Regional Anesthesia for Robotic Coronary Artery Bypass Surgery Is Not Associated With Reduced Postoperative Opioid Use: A Retrospective Observational Study. J Cardiothorac Vasc Anesth. 2021 Jul;35(7):2034-2042. doi: 10.1053/j.jvca.2020.09.112. Epub 2020 Sep 20.

  PMID: 33127286 RESULT

MeSH Terms

Conditions

Pain, Postoperative; Coronary Artery Disease

Interventions

Analgesics

Condition Hierarchy (Ancestors)

Postoperative Complications; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Pain; Neurologic Manifestations; Signs and Symptoms; Coronary Disease; Myocardial Ischemia; Heart Diseases; Cardiovascular Diseases; Arteriosclerosis; Arterial Occlusive Diseases; Vascular Diseases

Intervention Hierarchy (Ancestors)

Sensory System Agents; Peripheral Nervous System Agents; Physiological Effects of Drugs; Pharmacologic Actions; Chemical Actions and Uses; Central Nervous System Agents; Therapeutic Uses

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: NONE
• Purpose: SCREENING
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Hasan Huseyin Kilic

Study Record Dates

• First Submitted: August 20, 2024
• First Posted: September 5, 2024
• Study Start: September 1, 2024
• Primary Completion: April 30, 2025
• Study Completion: June 30, 2025
• Last Updated: December 9, 2025

Record last verified: 2024-08

Locations

TU (1)