Lumbar Erector Spinae Plane Block vs Fascia Iliaca Block vs Lumbar Plexus Block for Postoperative Analgesia for Total Hip Arthroplasty

NCT06573931 | Completed

• 1 other identifier: 36264PR760/7/24
• Study Type: interventional
• Target: 90
• Locations: 1 country
• Sites: 1

Brief Summary

This study aims to compare lumbar erector spinae plane block, fascia iliaca block, and lumbar plexus block for postoperative analgesia for hip surgery.

Conditions

Lumbar Erector Spinae Plane Block; Fascia Iliaca Block; Lumbar Plexus Block; Analgesia; Total Hip Arthroplasty

Outcome Measures

Primary Outcomes (1)

• Time to the 1st rescue analgesia

  Time to the first request for the rescue analgesia (time from end of block to first dose of morphine administrated) will be recorded.

  24 hours postoperatively

Secondary Outcomes (3)

• Total morphine consumption in the 1st 24h

  24 hours postoperatively

• Degree of pain

  24 hours postoperatively

• Incidence of adverse events

  24 hours postoperatively

Study Arms (3)

Lumbar Erector Spinae Plane Block

EXPERIMENTAL

Patients will receive lumbar erector spinae plane block at the end of surgery.

Other: Lumbar Erector Spinae Plane Block

Fascia Iliaca Block

EXPERIMENTAL

Patients will receive fascia iliaca block at the end of surgery.

Other: Fascia Iliaca Block

Lumbar Plexus Block

EXPERIMENTAL

Patients will receive lumbar plexus block at the end of surgery.

Other: Lumbar Plexus Block

Interventions

Lumbar Erector Spinae Plane Block OTHER

Patients will receive lumbar erector spinae plane block at the end of surgery.

Lumbar Erector Spinae Plane Block

Fascia Iliaca Block OTHER

Patients will receive fascia iliaca block at the end of surgery.

Fascia Iliaca Block

Lumbar Plexus Block OTHER

Patients will receive lumbar plexus block at the end of surgery.

Lumbar Plexus Block

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Age ≥ 18 years.
• Both sexes.
• American Society of Anesthesiology (ASA) physical status I-III.
• Undergoing total hip arthroplasty under spinal anesthesia.

You may not qualify if:

• Obesity (Body Mass Index \> 30 kg/m2).
• Allergy to any drug used in the study.
• Contraindications to spinal anesthesia (such as Thrombocytopenia (platelets \<100,000/mCL) and coagulopathy (INR \>1.4 or insufficient time since stopping systemic anticoagulation)).
• Epilepsy.
• Psychiatric disease.
• Pre-existing neurologic deficits or neuropathies.
• Pregnancy.
• Pre-existing alcohol/opioid use disorder.
• Previously diagnosed with chronic pain.

Sponsors & Collaborators

• Tanta University: lead

Study Sites (1)

Tanta University

Tanta, El-Gharbia, 31527, Egypt

Location

MeSH Terms

Conditions

Agnosia

Condition Hierarchy (Ancestors)

Perceptual Disorders; Neurobehavioral Manifestations; Neurologic Manifestations; Nervous System Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Lecturer of Anesthesiology, Surgical Intensive Care and Pain Medicine, Faculty of Medicine, Tanta University, Tanta, Egypt.

Study Record Dates

• First Submitted: August 24, 2024
• First Posted: August 27, 2024
• Study Start: August 29, 2024
• Primary Completion: February 15, 2025
• Study Completion: February 15, 2025
• Last Updated: April 18, 2025

Record last verified: 2025-04

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL
• Time Frame: After the end of study for one year.
• Access Criteria: The data will be available upon a reasonable request from the corresponding author.

Locations

EG (1)