Transverse Thoracic Plane Block, Midpoint Transverse Process Plane to Pleura Block and Erector Spinae Plane Block for Analgesia in Patients Undergoing Thoracoscopic Sympathectomy

NCT06987110 | Completed

• 1 other identifier: 36264PR1182/4/25.
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

This study compares the transversus thoracic muscle plane block (TTPB), midtransverse to pleura block (MTPB), and erector spinae plane block (ESPB) for postoperative analgesia in patients undergoing thoracoscopic sympathectomy.

Conditions

Transverse Thoracic Plane Block; Midpoint Transverse Process Plane to Pleura Block; Erector Spinae Plane Block; Analgesia; Thoracoscopic Sympathectomy

Outcome Measures

Primary Outcomes (1)

• Time to the 1st rescue analgesia

  Time to the first request for the rescue analgesia (time from end of surgery to first dose of morphine administrated)

  24 hours postoperatively

Secondary Outcomes (6)

• Total morphine consumption

  24 hours postoperatively

• Degree of pain

  24 hours postoperatively

• Heart rate

  Till the end of surgery (Up to 2 hours)

• Mean arterial pressure

  Till the end of surgery (Up to 2 hours)

• Degree of patient satisfaction

  24 hours postoperatively

Study Arms (3)

Transverse thoracic plane block group

EXPERIMENTAL

Patients will receive a transverse thoracic plane block.

Other: Transverse thoracic plane block

Midpoint transverse process plane to pleura block group

EXPERIMENTAL

Patients will receive a midpoint transverse process plane to pleura block.

Other: Midpoint transverse process plane to pleura block

Erector spinae plane block group

EXPERIMENTAL

Patients will receive an erector spinae plane block.

Other: Erector spinae plane block

Interventions

Transverse thoracic plane block OTHER

Patients will receive a transverse thoracic plane block.

Transverse thoracic plane block group

Midpoint transverse process plane to pleura block OTHER

Patients will receive a midpoint transverse process plane to pleura block.

Midpoint transverse process plane to pleura block group

Erector spinae plane block OTHER

Patients will receive an erector spinae plane block.

Erector spinae plane block group

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Age from 18 to 65 years.
• Both sexes.
• American Society of Anesthesiology (ASA) physical status I-II.
• Scheduled for thoracoscopic sympathectomy

You may not qualify if:

• Coagulopathy.
• History of opiate abuse.
• Pre-existing chronic pain.
• Allergy to local anesthetics or analgesics.
• Infection at the site of injection.
• Mental or neurological disorders.
• Pregnancy

Sponsors & Collaborators

• Tanta University: lead

Study Sites (1)

Tanta University

Tanta, El-Gharbia, 31527, Egypt

Location

MeSH Terms

Conditions

Agnosia

Condition Hierarchy (Ancestors)

Perceptual Disorders; Neurobehavioral Manifestations; Neurologic Manifestations; Nervous System Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Lecturer of Anesthesiology, Surgical Intensive Care and Pain Medicine, Faculty of Medicine, Tanta University, Tanta, Egypt.

Study Record Dates

• First Submitted: May 15, 2025
• First Posted: May 23, 2025
• Study Start: May 24, 2025
• Primary Completion: October 11, 2025
• Study Completion: October 11, 2025
• Last Updated: November 25, 2025

Record last verified: 2025-11

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL
• Time Frame: After the end of the study for one year.
• Access Criteria: The data will be available upon a reasonable request from the corresponding author.

Locations

EG (1)