NCT06573099

Brief Summary

The aim of this study is to prospectively collect clinical information on patients with extranodal lymphoma, and to explore the best therapeutic strategies in the real-world population.

Trial Health

65
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
5,000

participants targeted

Target at P75+ for all trials

Timeline
41mo left

Started Sep 2024

Longer than P75 for all trials

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress34%
Sep 2024Sep 2029

First Submitted

Initial submission to the registry

August 8, 2024

Completed
19 days until next milestone

First Posted

Study publicly available on registry

August 27, 2024

Completed
5 days until next milestone

Study Start

First participant enrolled

September 1, 2024

Completed
3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2027

Expected
2 years until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2029

Last Updated

August 27, 2024

Status Verified

August 1, 2024

Enrollment Period

3 years

First QC Date

August 8, 2024

Last Update Submit

August 23, 2024

Conditions

Keywords

LYMPHOMAEXTRANODALDLBCL

Outcome Measures

Primary Outcomes (1)

  • Progression Free Survival (PFS)

    Progression-Free Survival (PFS) will be defined from the date of starting therapy and the date of disease progression, relapse or death from any cause.

    Baseline up to data cut-off (up to approximately 1 year)

Secondary Outcomes (1)

  • Overall Survival (OS)

    Baseline up to data cut-off (up to approximately 1 year)

Interventions

No interventions need to be specified for this study

Eligibility Criteria

Age18 Years+
Sexall
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Adult patients with histologically confirmed diagnosis of non-Hodgkin lymphoma with extranodal involvement.

You may qualify if:

  • Age ≥ 18 years (including 18 years old).
  • Patients newly diagnosed with non-Hodgkin lymphoma with extranodal involvement, whether it is primary, secondary, or cannot be determined.
  • Patients who have received systematic clinical treatment.
  • Patients with measurable lesions, at least containing one effective evaluation of efficacy.

You may not qualify if:

  • Patients who only receive supportive treatment.
  • Patients who cannot obtain effective evaluation data of efficacy.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

LymphomaLymphoma, B-CellLymphoma, Non-HodgkinLymphoma, Large B-Cell, Diffuse

Condition Hierarchy (Ancestors)

Neoplasms by Histologic TypeNeoplasmsLymphoproliferative DisordersLymphatic DiseasesHemic and Lymphatic DiseasesImmunoproliferative DisordersImmune System Diseases

Central Study Contacts

Weili Zhao, MD, PhD

CONTACT

Pengpeng Xu, MD

CONTACT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
First Deputy Director, Hematology Department

Study Record Dates

First Submitted

August 8, 2024

First Posted

August 27, 2024

Study Start

September 1, 2024

Primary Completion (Estimated)

September 1, 2027

Study Completion (Estimated)

September 1, 2029

Last Updated

August 27, 2024

Record last verified: 2024-08