Key Insights

Highlights

Success Rate

78% trial completion

Published Results

94 trials with published results (29%)

Research Maturity

178 completed trials (55% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

15.8%

51 terminated out of 322 trials

Success Rate

77.7%

-8.8% vs benchmark

Late-Stage Pipeline

8%

27 trials in Phase 3/4

Results Transparency

53%

94 of 178 completed with results

Key Signals

94 with results78% success51 terminated

Data Visualizations

Phase Distribution

277Total
Not Applicable (24)
Early P 1 (1)
P 1 (129)
P 2 (96)
P 3 (22)
P 4 (5)

Trial Status

Completed178
Terminated51
Recruiting27
Active Not Recruiting24
Unknown21
Not Yet Recruiting10

Trial Success Rate

77.7%

Benchmark: 86.5%

Based on 178 completed trials

Clinical Trials (322)

Showing 20 of 20 trials
NCT06660563Phase 1Active Not RecruitingPrimary

A Study of JNJ-80948543 in Combination With Other CD3 T-Cell Engagers in Participants With Relapsed/Refractory B-Cell Non-Hodgkin Lymphoma (R/R B-Cell NHL)

NCT06470438Phase 1Active Not RecruitingPrimary

A Study of JNJ-88998377 for Relapsed/Refractory B-cell Non-Hodgkin's Lymphoma

NCT06788509Phase 1Enrolling By Invitation

A Rollover Study for Continued Study Treatment and Ongoing Safety Monitoring

NCT06139406Phase 1Active Not RecruitingPrimary

A Study of JNJ-87801493 in Combination With T-Cell Engagers in Participants With B-cell Non-Hodgkin Lymphoid (NHLs) Cancer

NCT05421663Phase 1Active Not RecruitingPrimary

A Study of JNJ-90014496 in Participants With B-Cell Non-Hodgkin Lymphoma

NCT05424822Phase 1Active Not RecruitingPrimary

A Study of JNJ-80948543, a T-cell Redirecting CD79b x CD20 x CD3 Trispecific Antibody, in Participants With Non-Hodgkin Lymphoma (NHL) and Chronic Lymphocytic Leukemia (CLL)

NCT01676805Recruiting

Tissue Collection for Studies of Lymph Cancer

NCT05442515Phase 1Recruiting

CD19/CD22 Bicistronic Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory B Cell Malignancies

NCT07735533Phase 1Not Yet Recruiting

A Phase 1/2 Study of UB-VV400 With Rapamycin in Relapsed/Refractory B-cell Malignancies

NCT02682667Recruiting

Biospecimen Procurement for Center for Immuno-Oncology Immunotherapy Protocols

NCT03598608Phase 1Terminated

Study to Evaluate the Safety and Efficacy of a Combination of Favezelimab (MK-4280) and Pembrolizumab (MK-3475) in Participants With Hematologic Malignancies (MK-4280-003)

NCT07519772Phase 1RecruitingPrimary

A Clinical Study of MK-1045 in People With Non-Hodgkin Lymphoma (MK-1045-008)

NCT04975555Phase 2Completed

Study to Evaluate the Role of Siltuximab in Treatment of Cytokine Release Syndrome (CRS) and Immune Effector Cell Associated Neurotoxicity (ICANS) Related to CAR-T Cell Therapy

NCT07721194CompletedPrimary

Primary Bone Mature B-Cell NHL in Children

NCT07713459Phase 2Not Yet RecruitingPrimary

A Phase II Study to Evaluate the Efficacy of UF-KURE19 Cells in Patients With Relapsed or Refractory B Cell Non-Hodgkin Lymphomas

NCT05024045Phase 1Completed

Study of Oral LOXO-338 in Patients With Advanced Blood Cancers

NCT03480360Phase 3Completed

Haploidentical Allogeneic Peripheral Blood Transplantation: Examining Checkpoint Immune Regulators' Expression

NCT04996706Enrolling By InvitationPrimary

Evaluation of Lymphoma Prognosis and Survivorship in Recently Diagnosed Patients, LEO Study

NCT07101328Phase 1RecruitingPrimary

A Study of LY4152199 in Participants With Previously Treated B-cell Malignancies (BAF_FRontier-1 )

NCT07308132Phase 1RecruitingPrimary

A Study of JNJ-95566692 in Participants With Non-Hodgkin Lymphoid Malignancies

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