Key Insights

Highlights

Success Rate

78% trial completion

Published Results

93 trials with published results (29%)

Research Maturity

176 completed trials (55% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

15.4%

49 terminated out of 318 trials

Success Rate

78.2%

-8.3% vs benchmark

Late-Stage Pipeline

8%

27 trials in Phase 3/4

Results Transparency

53%

93 of 176 completed with results

Key Signals

93 with results78% success49 terminated

Data Visualizations

Phase Distribution

275Total
Not Applicable (24)
Early P 1 (1)
P 1 (128)
P 2 (95)
P 3 (22)
P 4 (5)

Trial Status

Completed176
Terminated49
Recruiting27
Active Not Recruiting25
Unknown21
Not Yet Recruiting9

Trial Success Rate

78.2%

Benchmark: 86.5%

Based on 176 completed trials

Clinical Trials (318)

Showing 20 of 20 trials
NCT05442515Phase 1Recruiting

CD19/CD22 Bicistronic Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory B Cell Malignancies

NCT07519772Phase 1RecruitingPrimary

A Clinical Study of MK-1045 in People With Non-Hodgkin Lymphoma (MK-1045-008)

NCT02663297Phase 1Active Not Recruiting

Administration of T Lymphocytes for Prevention of Relapse of Lymphomas

NCT04935684Phase 2Recruiting

Faecal Microbiota Transplantation After Allogeneic Stem Cell Transplantation

NCT06139406Phase 1Active Not RecruitingPrimary

A Study of JNJ-87801493 in Combination With T-Cell Engagers in Participants With B-cell Non-Hodgkin Lymphoid (NHLs) Cancer

NCT02682667Recruiting

Biospecimen Procurement for Center for Immuno-Oncology Immunotherapy Protocols

NCT06470438Phase 1Active Not RecruitingPrimary

A Study of JNJ-88998377 for Relapsed/Refractory B-cell Non-Hodgkin's Lymphoma

NCT05424822Phase 1Active Not RecruitingPrimary

A Study of JNJ-80948543, a T-cell Redirecting CD79b x CD20 x CD3 Trispecific Antibody, in Participants With Non-Hodgkin Lymphoma (NHL) and Chronic Lymphocytic Leukemia (CLL)

NCT06788509Phase 1Enrolling By Invitation

A Rollover Study for Continued Study Treatment and Ongoing Safety Monitoring

NCT05421663Phase 1RecruitingPrimary

A Study of JNJ-90014496 in Participants With B-Cell Non-Hodgkin Lymphoma

NCT07308132Phase 1RecruitingPrimary

A Study of JNJ-95566692 in Participants With Non-Hodgkin Lymphoid Malignancies

NCT06660563Phase 1Active Not RecruitingPrimary

A Study of JNJ-80948543 in Combination With Other CD3 T-Cell Engagers in Participants With Relapsed/Refractory B-Cell Non-Hodgkin Lymphoma (R/R B-Cell NHL)

NCT05800210Phase 2Recruiting

Alpha/Beta T Cell and CD19+ B Cell Depletion in Allogeneic Stem Cell Transplantation in Patients With Malignant Diseases

NCT04975555Phase 2Completed

Study to Evaluate the Role of Siltuximab in Treatment of Cytokine Release Syndrome (CRS) and Immune Effector Cell Associated Neurotoxicity (ICANS) Related to CAR-T Cell Therapy

NCT04077723Phase 1Active Not RecruitingPrimary

A Study to Evaluate the Safety, Pharmacokinetics and Preliminary Anti-Tumor Activity of Englumafusp Alfa in Combination With Obinutuzumab and in Combination With Glofitamab Following a Pre-Treatment Dose of Obinutuzumab in Participants With Relapsed/Refractory B-Cell Non-Hodgkin's Lymphoma

NCT02693535Phase 2RecruitingPrimary

TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer

NCT04460235Phase 4Recruiting

Clinical Trial Assessing the Immunogenicity of an Anti-pneumococcal Vaccination Strategy (PCV13+PPV23 Versus PREVENAR20) in Adult Patients Treated for a Lymphoma

NCT05515406Phase 1TerminatedPrimary

A Study to Investigate the Safety, Tolerability, PK, PD, and Efficacy of ONO-7018 in Patients With R/R NHL or CLL

NCT07607925Phase 1Not Yet RecruitingPrimary

A Study to Evaluate Safety and Clinical Activity of GSK5926371 in Adult Participants With Relapsed or Refractory B-NHL

NCT06458439Phase 2RecruitingPrimary

Epcoritamab-CAR T Cells for Large B-cell Lymphomas

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