Key Insights

Highlights

Success Rate

78% trial completion

Published Results

21 trials with published results (8%)

Research Maturity

69 completed trials (26% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

7.4%

20 terminated out of 269 trials

Success Rate

77.5%

-9.0% vs benchmark

Late-Stage Pipeline

7%

19 trials in Phase 3/4

Results Transparency

30%

21 of 69 completed with results

Key Signals

21 with results78% success20 terminated

Data Visualizations

Phase Distribution

219Total
Not Applicable (21)
Early P 1 (5)
P 1 (94)
P 2 (80)
P 3 (14)
P 4 (5)

Trial Status

Completed69
Unknown63
Recruiting57
Active Not Recruiting32
Terminated20
Withdrawn12

Trial Success Rate

77.5%

Benchmark: 86.5%

Based on 69 completed trials

Clinical Trials (269)

Showing 20 of 20 trials
NCT06323447Active Not RecruitingPrimary

Pivotal Study to Validate a Novel System to Non-Invasively Detect Severe Neutropenia

NCT04263584Phase 2CompletedPrimary

Copanlisib in Combination With Rituximab and CHOP Chemotherapy in Patients With Previously Untreated DLBCL

NCT05365659Phase 1Recruiting

IKS03 in Patients With Advanced B Cell Non-Hodgkin Lymphomas

NCT05725720Active Not RecruitingPrimary

Role of the Gut Microbiome in the Outcome of Diffuse Large B-Cell Lymphoma Patients Treated With CAR-T Cell Therapy

NCT05006716Phase 1Recruiting

A Dose-Escalation and Expansion Study of BGB-16673 in Participants With B-Cell Malignancies

NCT03226704Enrolling By Invitation

Leukapheresis for CAR or Adoptive Cell Therapy Manufacturing

NCT04104776Phase 1Recruiting

A Study of Tulmimetostat DZR123 (CPI-0209) in Patients With Advanced Solid Tumors and Lymphomas

NCT05665062Phase 1Active Not Recruiting

Autologous CD19 CAR-T Cell Therapy (SYNCAR-001) + Orthogonal IL-2 (STK-009) in Subjects With CD19+ Hematologic Malignancies

NCT07225439Phase 1Not Yet Recruiting

Rituximab (Rtx) + Tafasitamab in Combination With Allogeneic NK Cells for Treatment of Relapsed/Refractory (r/r) B-cell Non-Hodgkin Lymphoma (NHL)

NCT03681535Not ApplicableActive Not RecruitingPrimary

Dose-Reduced Consolidation Radiation Therapy in Patients With Diffuse Large B-cell Lymphoma

NCT04542824Phase 1Active Not RecruitingPrimary

Trial of the Safety and Efficacy of Epcoritamab in Japanese Subjects With Relapsed or Refractory (R/R) B-Cell Non-Hodgkin Lymphoma (R/R B-NHL)

NCT06227026Phase 1Recruiting

Pilot Study of Anti-CD19 Chimeric Antigen Receptor T Cells (CAR-T Cells) for the Treatment of Relapsed/Refractory CD19+ Malignancies

NCT06694779CompletedPrimary

Thrombosis in Diffuse Large B-cell Lymphoma:the PREDIC-TO (PREDICt ThrOmbosis) Study

NCT05820841Phase 3Recruiting

Acalabrutinib in Combination With R-miniCHOP in Older Adults With Untreated Diffuse Large B-Cell Lymphoma

NCT04545762Phase 1Recruiting

Anti-CD19 Chimeric Antigen Receptor T Cells for Treatment of Relapsed or Refractory Non-Hodgkin Lymphoma

NCT06352242Not ApplicableRecruitingPrimary

Is Trogocytosis a Predictive Marker of CAR-T Cell Response in Diffuse Large B-cell Lymphoma?

NCT04594642Phase 1Active Not Recruiting

A Study of AZD0486 in Subjects With B-Cell Non-Hodgkin Lymphoma

NCT05934838Phase 1Active Not Recruiting

A Feasibility Trial of Tazemetostat Plus CAR T Cell Therapy in B-cell Lymphomas

NCT03162536Phase 1Active Not Recruiting

A Study of Nemtabrutinib (MK-1026) in Participants With Relapsed or Refractory Hematologic Malignancies (ARQ 531-101/MK-1026-001)

NCT06131801Recruiting

Pharmacokinetic Study of Venetoclax Tablets Crushed and Dissolved Into a Solution

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