Key Insights

Highlights

Success Rate

78% trial completion

Published Results

20 trials with published results (7%)

Research Maturity

67 completed trials (25% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

7.1%

19 terminated out of 269 trials

Success Rate

77.9%

-8.6% vs benchmark

Late-Stage Pipeline

7%

19 trials in Phase 3/4

Results Transparency

30%

20 of 67 completed with results

Key Signals

20 with results78% success19 terminated

Data Visualizations

Phase Distribution

219Total
Not Applicable (21)
Early P 1 (5)
P 1 (94)
P 2 (80)
P 3 (14)
P 4 (5)

Trial Status

Completed67
Unknown65
Recruiting61
Active Not Recruiting27
Terminated19
Not Yet Recruiting14

Trial Success Rate

77.9%

Benchmark: 86.5%

Based on 67 completed trials

Clinical Trials (269)

Showing 20 of 20 trials
NCT06768905Phase 1Recruiting

IOMAB-CAR-T Followed by CAR-T Cell Therapy in R/R DLBCL

NCT05006716Phase 1Recruiting

A Dose-Escalation and Expansion Study of BGB-16673 in Participants With B-Cell Malignancies

NCT04491370Phase 1Recruiting

Autologous Stem Cell Transplant Followed by Polatuzumab Vedotin in Patients With B-cell Non-Hodgkin and Hodgkin Lymphoma

NCT07476105Not ApplicableNot Yet RecruitingPrimary

Geriatric-guided Care Versus Conventional Care in Elderly Unfit/Frail Patients With Diffuse Large B-cell Lymphoma in First Line Treatment

NCT03226704Enrolling By Invitation

Leukapheresis for CAR or Adoptive Cell Therapy Manufacturing

NCT07528352Phase 1Not Yet RecruitingPrimary

External Beam Radiotherapy Followed by Bispecific Antibody Therapy for Relapsed/Refractory DLBCL

NCT06544265Phase 1Recruiting

SynKIR-310 for Relapsed/Refractory B-NHL

NCT04911478Active Not Recruiting

Long-term Follow-up Study of Allogeneic Gamma Delta (γδ) CAR T Cells

NCT01241734Phase 1CompletedPrimary

Study of Lenalidomide in Combination With RICE With Lenalidomide Maintenance Post-Auto Transplant for DLBCL

NCT04542824Phase 1Active Not RecruitingPrimary

Trial of the Safety and Efficacy of Epcoritamab in Japanese Subjects With Relapsed or Refractory (R/R) B-Cell Non-Hodgkin Lymphoma (R/R B-NHL)

NCT06451497Phase 1Recruiting

This is a Phase 1 Trial of ZM008, an Anti-LLT1 Antibody, Used as Single Agent Followed by Combination Treatment With Toripalimab in Patients With Advanced Solid Tumors

NCT05618366Phase 1Terminated

Tazemetostat and Venetoclax in Relapsed/Refractory Non-Hodgkin Lymphoma

NCT07502872Phase 2Not Yet RecruitingPrimary

TPG: Tafasitamab, Polatuzumab Vedotin, and Glofitamab as First-line Therapy for Diffuse Large B-cell Lymphoma and High-grade B-cell Lymphoma

NCT05757219Phase 2RecruitingPrimary

Itacitinib Pre-modulation in DLBCL Receiving CAR T Cell Therapy

NCT06687772Phase 2RecruitingPrimary

CNS-Relapse Prevention in High-Risk Diffuse Large B-cell Lymphoma With Thiotepa-based Autologous Stem Cell Transplant

NCT06533579Phase 1Recruiting

Gene Therapy for CD19-Positive Hematologic Malignancies (SENTRY-CD19)

NCT05514327Not ApplicableRecruitingPrimary

A Study of Ultra-fraction Radiotherapy Bridging CART in R/R DLBCL

NCT02952508Phase 2Active Not Recruiting

Study of Iopofosine I-131 (CLR 131) in Select B-Cell Malignancies (CLOVER-1) With Expansion in Waldenstrom

NCT04594642Phase 1Recruiting

A Study of AZD0486 in Subjects With B-Cell Non-Hodgkin Lymphoma

NCT01679119Phase 2CompletedPrimary

Treatment of Patients With Diffuse Large B Cell Lymphoma Who Are Not Suitable for Anthracycline Containing Chemotherapy

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