Key Insights

Highlights

Success Rate

72% trial completion

Published Results

28 trials with published results (20%)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

13.9%

19 terminated out of 137 trials

Success Rate

71.6%

-14.9% vs benchmark

Late-Stage Pipeline

4%

6 trials in Phase 3/4

Results Transparency

58%

28 of 48 completed with results

Key Signals

28 with results72% success19 terminated

Data Visualizations

Phase Distribution

124Total
Not Applicable (14)
Early P 1 (2)
P 1 (62)
P 2 (40)
P 3 (3)
P 4 (3)

Trial Status

Completed48
Unknown24
Recruiting20
Terminated19
Active Not Recruiting12
Withdrawn9

Trial Success Rate

71.6%

Benchmark: 86.5%

Based on 48 completed trials

Clinical Trials (137)

Showing 20 of 20 trials
NCT03162536Phase 1Active Not RecruitingPrimary

A Study of Nemtabrutinib (MK-1026) in Participants With Relapsed or Refractory Hematologic Malignancies (ARQ 531-101/MK-1026-001)

NCT07188558Phase 3Recruiting

A Study to Investigate Ronde-cel Versus Investigator's Choice CD19 CAR T-Cell Therapy

NCT04884035Phase 1RecruitingPrimary

Study of Safety and Efficacy of Iberdomide (CC-220) and CC-99282 Combined With R-CHOP to Treat Lymphoma

NCT06381830Phase 2TerminatedPrimary

Clinical Study of CAR-T Cell Therapy Following ASCT for R/R B-cell Non-Hodgkin's Lymphoma

NCT05421663Phase 1Recruiting

A Study of JNJ-90014496 in Participants With B-Cell Non-Hodgkin Lymphoma

NCT01087294Phase 1Completed

Administration of Anti-CD19-chimeric-antigen-receptor-transduced T Cells From the Original Transplant Donor to Patients With Recurrent or Persistent B-cell Malignancies After Allogeneic Stem Cell Transplantation

NCT06528301Phase 1RecruitingPrimary

A Phase 1 Study of UB-VV111 With and Without Rapamycin in Relapsed/Refractory CD19+ B-cell Malignancies

NCT06954805Phase 2Recruiting

Defining ctDNA Metrics in Posttransplant Lymphoproliferative Disorder (PTLD)

NCT04161248Early Phase 1Active Not RecruitingPrimary

Phase I Master Protocol of Novel Combination Therapy for Patients With Relapsed or Refractory Aggressive B-Cell Lymphoma

NCT05797233Phase 1Active Not Recruiting

Trial of Anti-CD19 and Anti-CD20 Bicistronic Chimeric Antigen Receptor T Cells for Treating B-Cell Malignancies

NCT05463263Phase 1RecruitingPrimary

A Phase 1/2 Study of STP938 for Adult Subjects With Relapsed/Refractory B-Cell and T-Cell Lymphomas

NCT07502872Phase 2Not Yet Recruiting

TPG: Tafasitamab, Polatuzumab Vedotin, and Glofitamab as First-line Therapy for Diffuse Large B-cell Lymphoma and High-grade B-cell Lymphoma

NCT04629729Phase 1Active Not RecruitingPrimary

FT819 in Subjects With B-cell Malignancies

NCT05540340Phase 1Active Not Recruiting

A Study of Melphalan in People With Lymphoma Getting an Autologous Hematopoietic Cell Transplant

NCT04842877Phase 2Active Not RecruitingPrimary

Study of Valemetostat Tosylate as a Single Agent in Patients With Relapse/Refractory B-cell Lymphoma

NCT04849416Phase 2Completed

A Study of LOXO-305 in Chinese Participants With Blood Cancer (Including Lymphoma and Chronic Leukemia)

NCT03598608Phase 1Completed

Study to Evaluate the Safety and Efficacy of a Combination of Favezelimab (MK-4280) and Pembrolizumab (MK-3475) in Participants With Hematologic Malignancies (MK-4280-003)

NCT05784415Completed

Observational Study of People Living With HIV Treated With CD19-directed CAR T Cell

NCT06693830Not ApplicableRecruiting

ctDNA-guided Therapy Optimization in Newly Diagnosed DLBCL

NCT04594798Phase 2Active Not Recruiting

A Study of Polatuzumab Vedotin, Rituximab and Dose Attenuated CHP in Older Patients With DLBCL

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