Key Insights

Highlights

Success Rate

83% trial completion

Published Results

418 trials with published results (20%)

Research Maturity

1173 completed trials (57% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 72/100

Termination Rate

11.9%

243 terminated out of 2045 trials

Success Rate

82.8%

-3.7% vs benchmark

Late-Stage Pipeline

9%

176 trials in Phase 3/4

Results Transparency

36%

418 of 1173 completed with results

Key Signals

418 with results83% success243 terminated

Data Visualizations

Phase Distribution

1,749Total
Not Applicable (247)
Early P 1 (21)
P 1 (667)
P 2 (638)
P 3 (154)
P 4 (22)

Trial Status

Completed1,173
Terminated243
Unknown232
Recruiting185
Withdrawn89
Active Not Recruiting76

Trial Success Rate

82.8%

Benchmark: 86.5%

Based on 1173 completed trials

Clinical Trials (2045)

Showing 20 of 20 trials
NCT07524530Phase 2Not Yet Recruiting

Stem Cell Transplantation for Participants With Germline RUNX1 Associated Blood Cancers

NCT03602157Phase 1Active Not RecruitingPrimary

Study of CAR-T Cells Expressing CD30 and CCR4 for r/r CD30+ HL and CTCL

NCT07014293Not ApplicableNot Yet RecruitingPrimary

Increasing Resiliency Among Early Post-Treatment Lymphoma Survivors

NCT07302347Phase 1Recruiting

A Study of Pembrolizumab in Japanese Pediatric Participants With Solid Tumors or Lymphomas and Japanese Adult Participants With Merkel Cell Carcinoma (MK-3475-G21/KEYNOTE-G21)

NCT05673785Phase 2Active Not RecruitingPrimary

A Study of Brentuximab Vedotin in Combination With Cyclophosphamide, Doxorubicin (Hydroxydaunorubicin), Prednisone (CHP) in Chinese Participants With CD30-Positive (CD30+) Peripheral T-Cell Lymphomas (PTCL)

NCT01430390Phase 1Active Not Recruiting

In Vitro Expanded Allogeneic Epstein-Barr Virus Specific Cytotoxic T-Lymphocytes (EBV-CTLs) Genetically Targeted to the CD19 Antigen in B-cell Malignancies

NCT03226704Enrolling By Invitation

Leukapheresis for CAR or Adoptive Cell Therapy Manufacturing

NCT07015242Phase 2RecruitingPrimary

A Study of the Efficacy and Safety of Lisocabtagene Maraleucel (Liso-cel) as First-Line Therapy in Adults With Transplant-Ineligible Primary Central Nervous System Lymphoma

NCT05237986RecruitingPrimary

Cognitive Aftereffects of Neurotoxicity in Children and Young Adults With Relapsed/Refractory Hematologic Malignancies Who Receive CAR T-cell Therapy

NCT05403177Recruiting

Marathon of Hope Cancer Centres Network Study for Ontario (MOHCCN-O)

NCT02663297Phase 1Active Not Recruiting

Administration of T Lymphocytes for Prevention of Relapse of Lymphomas

NCT05891821Phase 2RecruitingPrimary

Assessment of the Safety and Efficacy of Balstilimab for the Treatment of Relapsed/Refractory Lymphomas (IMMONC0001)

NCT06643221Early Phase 1Recruiting

Exercise as an Immune Adjuvant for Allogeneic Cell Therapies

NCT03258567Phase 2Recruiting

Nivolumab in Epstein-Barr Virus (EBV)-Positive Lymphoproliferative Disorders and EBV-Positive Non-HodgkinLymphomas

NCT07628634Early Phase 1Recruiting

Feasibility Study on the Effect of a Methionine-Reduced Diet on Serum Levels in Pts w/ Solid Tumors

NCT03223610Phase 1RecruitingPrimary

Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Revlimid (ViPOR) in Relapsed/Refractory B-cell Lymphoma

NCT06131801Recruiting

Pharmacokinetic Study of Venetoclax Tablets Crushed and Dissolved Into a Solution

NCT05751798Phase 1Recruiting

Dose-finding and Dose Expansion Study of OSE-279 in Subjects With Advanced Solid Tumors or Lymphomas

NCT02465060Phase 2Active Not Recruiting

Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)

NCT06084936Phase 3RecruitingPrimary

A Study to Evaluate Glofitamab as a Single Agent vs. Investigator's Choice in Participants With Relapsed/Refractory Mantle Cell Lymphoma

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