A Study Evaluating Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASH
A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Safety and Efficacy of Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASH
1 other identifier
interventional
2,150
19 countries
318
Brief Summary
This is a multi-center evaluation of efruxifermin (EFX) in a randomized, double-blind, placebo-controlled study in subjects with compensated cirrhosis due to NASH/MASH.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for phase_3
Started Sep 2024
Longer than P75 for phase_3
318 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
June 28, 2024
CompletedFirst Posted
Study publicly available on registry
July 30, 2024
CompletedStudy Start
First participant enrolled
September 4, 2024
CompletedPrimary Completion
Last participant's last visit for primary outcome
February 1, 2030
ExpectedStudy Completion
Last participant's last visit for all outcomes
March 1, 2030
April 24, 2026
April 1, 2026
5.4 years
June 28, 2024
April 21, 2026
Conditions
Outcome Measures
Primary Outcomes (2)
Time from randomization to the first significant clinical event including disease progression, liver decompensation events, etc.
Measured by composite of protocol-specified clinical events
5 years
Cohort 1 only: Proportion of subjects with ≥ 1 stage improvement in fibrosis and no worsening of steatohepatitis
Based on NASH CRN fibrosis score (scored by a fibrosis score of 0-4, where 0 = no fibrosis, 1 = centrilobular pericellular fibrosis, 2 = centrilobular and periportal fibrosis, 3 = bridging fibrosis, 4 = cirrhosis)
96 Weeks
Secondary Outcomes (19)
Change from baseline of non-invasive markers of liver fibrosis
96 Weeks, 5 Years
Change from baseline of non-invasive markers of liver fibrosis
96 Weeks, 5 Years
Change from baseline of non-invasive markers of liver fibrosis
96 Weeks, 5 Years
Change from baseline of markers of liver injury
96 Weeks, 5 Years
Change from baseline of lipoproteins
96 Weeks, 5 Years
- +14 more secondary outcomes
Study Arms (2)
EFX 50 mg
EXPERIMENTALPlacebo
PLACEBO COMPARATORInterventions
Eligibility Criteria
You may qualify if:
- Cohort 1: Biopsy proven compensated cirrhosis (fibrosis stage 4) due to NASH/MASH and NAS score of \>=3 (at least 1 in each category) or evidence of steatosis and 2 current features of metabolic comorbidities
- Cohort 2: Biopsy proven or non-invasively diagnosed compensated cirrhosis (fibrosis stage 4) due to NASH/MASH
You may not qualify if:
- Other causes of liver disease based on medical history and/or liver histology and/or central laboratory results
- Type 1 diabetes or unstable Type 2 diabetes
- Any current or prior history of decompensated liver disease
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (318)
Akero Clinical Study Site
Birmingham, Alabama, 35209, United States
Akero Clinical Study Site
Dothan, Alabama, 36301, United States
Akero Clinical Study Site
Chandler, Arizona, 85224, United States
Akero Clinical Study Site
Flagstaff, Arizona, 86001, United States
Akero Clinical Study Site
Peoria, Arizona, 85381, United States
Akero Clinical Study Site
Scottsdale, Arizona, 85258, United States
Akero Clinical Study Site
Tucson, Arizona, 85712, United States
Akero Clinical Study Site
Tucson, Arizona, 85712, United States
Akero Clinical Study Site
Tucson, Arizona, 85713, United States
Akero Clinical Study Site
Tucson, Arizona, 85715, United States
Akero Clinical Study Site
Conway, Arkansas, 72032, United States
Akero Clinical Study Site
Jonesboro, Arkansas, 72401, United States
Akero Clinical Study Site
Little Rock, Arkansas, 72205, United States
Akero Clinical Study Site
North Little Rock, Arkansas, 72117, United States
Akero Clinical Study Site
Coronado, California, 92118, United States
Akero Clinical Study Site
Escondido, California, 92025, United States
Akero Clinical Study Site
Folsom, California, 95630, United States
Akero Clinical Study Site
Lancaster, California, 93534, United States
Akero Clinical Study Site
Long Beach, California, 90815, United States
Akero Clinical Study Site
Los Angeles, California, 90048, United States
Akero Clinical Study Site
Newport Beach, California, 92663, United States
Akero Clinical Study Site
Orange, California, 92868, United States
Akero Clinical Study Site
Pasadena, California, 91105, United States
Akero Clinical Study Site
Redwood City, California, 94063, United States
Akero Clinical Study Site
Sacramento, California, 95817, United States
Akero Clinical Study Site
San Francisco, California, 94115, United States
Akero Clinical Study Site
San Francisco, California, 94117, United States
Akero Clinical Study Site
San Jose, California, 95116, United States
Akero Clinical Study Site
Tarzana, California, 91356, United States
Akero Clinical Study Site
Aurora, Colorado, 80045, United States
Akero Clinical Study Site
Colorado Springs, Colorado, 80907, United States
Akero Clinical Study Site
Englewood, Colorado, 80113, United States
Akero Clinical Study Site
New Haven, Connecticut, 06511, United States
Akero Clinical Study Site
Washington D.C., District of Columbia, 20422, United States
Akero Clinical Study Site
Bradenton, Florida, 34208, United States
Akero Clinical Study Site
Brandon, Florida, 33511, United States
Akero Clinical Study Site
Cutler Bay, Florida, 33189, United States
Akero Clinical Study Site
Doral, Florida, 33126, United States
Akero Clinical Study Site
Fort Myers, Florida, 33912, United States
Akero Clinical Study Site
Hialeah Gardens, Florida, 33016, United States
Akero Clinical Study Site
Inverness, Florida, 34452, United States
Akero Clinical Study Site
Lakewood Rch, Florida, 34211, United States
Akero Clinical Study Site
Largo, Florida, 33777, United States
Akero Clinical Study Site
Lehigh Acres, Florida, 33936, United States
Akero Clinical Study Site
Margate, Florida, 33063, United States
Akero Clinical Study Site
Miami, Florida, 33136, United States
Akero Clinical Study Site
Miami, Florida, 33175, United States
Akero Clinical Study Site
Miami Gardens, Florida, 33014, United States
Akero Clinical Study Site
Naples, Florida, 34102, United States
Akero Clinical Study Site
New Port Richey, Florida, 34653, United States
Akero Clinical Study Site
Ocala, Florida, 34471, United States
Akero Clinical Study Site
Orlando, Florida, 32806, United States
Akero Clinical Study Site
Orlando, Florida, 32807, United States
Akero Clinical Study Site
Pembroke Pines, Florida, 33027, United States
Akero Clinical Study Site
Riverview, Florida, 33578, United States
Akero Clinical Study Site
Sarasota, Florida, 34240, United States
Akero Clinical Study Site
Temple Terrace, Florida, 33617, United States
Akero Clinical Study Site
Venice, Florida, 34285, United States
Akero Clinical Study Site
Viera, Florida, 32940, United States
Akero Clinical Study Site
Weston, Florida, 33331, United States
Akero Clinical Study Site
Zephyrhills, Florida, 33542, United States
Akero Clinical Study Site
Atlanta, Georgia, 30309, United States
Akero Clinical Study Site
Gainesville, Georgia, 30501, United States
Akero Clinical Study Site
Marietta, Georgia, 30060, United States
Akero Clinical Study Site
Snellville, Georgia, 30078, United States
Akero Clinical Study Site
Chicago, Illinois, 60611, United States
Akero Clinical Study Site
Hammond, Indiana, 46324, United States
Akero Clinical Study Site
Indianapolis, Indiana, 46202, United States
Akero Clinical Study Site
South Bend, Indiana, 46635, United States
Akero Clinical Study Site
West Des Moines, Iowa, 50265, United States
Akero Clinical Study Site
Topeka, Kansas, 66606, United States
Akero Clinical Study Site
Louisville, Kentucky, 40202, United States
Akero Clinical Study Site
Bastrop, Louisiana, 71220, United States
Akero Clinical Study Site
Covington, Louisiana, 70433, United States
Akero Clinical Study Site
Houma, Louisiana, 70363, United States
Akero Clinical Study Site
Lafayette, Louisiana, 70503, United States
Akero Clinical Study Site
Marrero, Louisiana, 70072, United States
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Metairie, Louisiana, 70006, United States
Akero Clinical Study Site
Shreveport, Louisiana, 71105, United States
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West Monroe, Louisiana, 71291, United States
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Baltimore, Maryland, 21202, United States
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Bethesda, Maryland, 20889-0004, United States
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Russells Mills, Massachusetts, 02747, United States
Akero Clinical Study Site
Clinton Township, Michigan, 48038, United States
Akero Clinical Study Site
Novi, Michigan, 48377, United States
Akero Clinical Study Site
Southfield, Michigan, 48075, United States
Akero Clinical Study Site
Rochester, Minnesota, 55905, United States
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Flowood, Mississippi, 39232, United States
Akero Clinical Study Site
Columbia, Missouri, 65201, United States
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Kansas City, Missouri, 64131, United States
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St Louis, Missouri, 63110, United States
Akero Clinical Study Site
St Louis, Missouri, 63123, United States
Akero Clinical Study Site
Las Vegas, Nevada, 89106, United States
Akero Clinical Study Site
Jackson, New Jersey, 08527, United States
Akero Clinical Study Site
Somers Point, New Jersey, 08244, United States
Akero Clinical Study Site
Sparta, New Jersey, 07871, United States
Akero Clinical Study Site
Buffalo, New York, 14203, United States
Akero Clinical Study Site
Manhasset, New York, 11030, United States
Akero Clinical Study Site
New York, New York, 10016, United States
Akero Clinical Study Site
New York, New York, 10021, United States
Akero Clinical Study Site
New York, New York, 10029, United States
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Rochester, New York, 14642, United States
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Chapel Hill, North Carolina, 27516, United States
Akero Clinical Study Site
Charlotte, North Carolina, 28204, United States
Akero Clinical Study Site
Charlotte, North Carolina, 28207, United States
Akero Clinical Study Site
Durham, North Carolina, 27710, United States
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Fayetteville, North Carolina, 28304, United States
Akero Clinical Study Site
Morehead City, North Carolina, 28557, United States
Akero Clinical Study Site
Raleigh, North Carolina, 27612, United States
Akero Clinical Study Site
Statesville, North Carolina, 28625, United States
Akero Clinical Study Site
Akron, Ohio, 44320, United States
Akero Clinical Study Site
Springboro, Ohio, 45066, United States
Akero Clinical Study Site
Westlake, Ohio, 44145, United States
Akero Clinical Study Site
Oklahoma City, Oklahoma, 73112, United States
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Hershey, Pennsylvania, 17033, United States
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Philadelphia, Pennsylvania, 19104, United States
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Philadelphia, Pennsylvania, 19107, United States
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Pittsburgh, Pennsylvania, 15213, United States
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Charleston, South Carolina, 29425, United States
Akero Clinical Study Site
Columbia, South Carolina, 29204, United States
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Summerville, South Carolina, 29485, United States
Akero Clinical Study Site
Clarksville, Tennessee, 37040, United States
Akero Clinical Study Site
Hermitage, Tennessee, 37076, United States
Akero Clinical Study Site
Nashville, Tennessee, 37211, United States
Akero Clinical Study Site
Amarillo, Texas, 79106, United States
Akero Clinical Study Site
Austin, Texas, 78745, United States
Akero Clinical Study Site
Austin, Texas, 78757, United States
Akero Clinical Study Site
Austin, Texas, 78757, United States
Akero Clinical Study Site
Bellaire, Texas, 77401, United States
Akero Clinical Study Site
Brownsville, Texas, 78520, United States
Akero Clinical Study Site
Corpus Christi, Texas, 78404, United States
Akero Clinical Study Site
Dallas, Texas, 75203, United States
Akero Clinical Study Site
Dallas, Texas, 75216, United States
Akero Clinical Study Site
Dallas, Texas, 75234, United States
Akero Clinical Study Site
Dallas, Texas, 75246, United States
Akero Clinical Study Site
Dallas, Texas, 75390, United States
Akero Clinical Study Site
Denison, Texas, 75020, United States
Akero Clinical Study Site
Edinburg, Texas, 78539, United States
Akero Clinical Study Site
Edinburg, Texas, 78539, United States
Akero Clinical Study Site
Fort Sam Houston, Texas, 78234, United States
Akero Clinical Study Site
Fort Worth, Texas, 76104, United States
Akero Clinical Study Site
Garland, Texas, 75044, United States
Akero Clinical Study Site
Houston, Texas, 77030, United States
Akero Clinical Study Site
Houston, Texas, 77030, United States
Akero Clinical Study Site
Houston, Texas, 77030, United States
Akero Clinical Study Site
Houston, Texas, 77074, United States
Akero Clinical Study Site
Houston, Texas, 77079, United States
Akero Clinical Study Site
Pasadena, Texas, 77505, United States
Akero Clinical Study Site
Pharr, Texas, 78577, United States
Akero Clinical Study Site
San Antonio, Texas, 78222, United States
Akero Clinical Study Site
San Antonio, Texas, 78229, United States
Akero Clinical Study Site
San Antonio, Texas, 78229, United States
Akero Clinical Study Site
San Antonio, Texas, 78251, United States
Akero Clinical Study Site
Sugar Land, Texas, 77478, United States
Akero Clinical Study Site
Sugar Land, Texas, 77478, United States
Akero Clinical Study Site
Waco, Texas, 76710, United States
Akero Clinical Study Site
Waco, Texas, 76712, United States
Akero Clinical Study Site
Webster, Texas, 77598, United States
Akero Clinical Study Site
Wichita Falls, Texas, 76301, United States
Akero Clinical Study Site
Norfolk, Virginia, 23502, United States
Akero Clinical Study Site
Richmond, Virginia, 23226-1925, United States
Akero Clinical Study Site
Richmond, Virginia, 23236, United States
Akero Clinical Study Site
Richmond, Virginia, 23249, United States
Akero Clinical Study Site
Richmond, Virginia, 23284, United States
Akero Clinical Study Site
Roanoke, Virginia, 24014, United States
Akero Clinical Study Site
Seattle, Washington, 98105, United States
Akero Clinical Study Site
Madison, Wisconsin, 53705, United States
Akero Clinical Study Site
Buenos Aires, Buenos Aires, C1180AAX, Argentina
Akero Clinical Study Site
Ciudad Autónoma de Buenos Aires, Buenos Aires, C1056ABI, Argentina
Akero Clinical Study Site
Ciudad Autónoma de Buenos Aires, Buenos Aires, C1199ABB, Argentina
Akero Clinical Study Site
La Plata, Buenos Aires, B1902AWL, Argentina
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Ramos Mejía, Buenos Aires, B1704ETD, Argentina
Akero Clinical Study Site
Buenos Aires, Distrito Federal, C1406EEI, Argentina
Akero Clinical Study Site
Rosario, Sante Fe, S2002KDT, Argentina
Akero Clinical Study Site
Broadmeadow, New South Wales, 2292, Australia
Akero Clinical Study Site
Kingswood, New South Wales, 2747, Australia
Akero Clinical Study Site
Liverpool, New South Wales, 1871, Australia
Akero Clinical Study Site
Westmead, New South Wales, 2145, Australia
Akero Clinical Study Site
Herston, Queensland, 4029, Australia
Akero Clinical Study Site
Adelaide, South Australia, 5000, Australia
Akero Clinical Study Site
Box Hill, Victoria, 3128, Australia
Akero Clinical Study Site
Clayton, Victoria, 3168, Australia
Akero Clinical Study Site
Epping, Victoria, 3076, Australia
Akero Clinical Study Site
Heidelberg, Victoria, 3084, Australia
Akero Clinical Study Site
Melbourne, Victoria, 3004, Australia
Akero Clinical Study Site
Murdoch, Western Australia, 6150, Australia
Akero Clinical Study Site
Nedlands, Western Australia, 6009, Australia
Akero Clinical Study Site
Perth, Western Australia, 6000, Australia
Akero Clinical Study Site
Brasília, Federal District, 71681-603, Brazil
Akero Clinical Study Site
Goiânia, Goiás, 74690-900, Brazil
Akero Clinical Study Site
Belo Horizonte, Minas Gerais, 30220-140, Brazil
Akero Clinical Study Site
Porto Alegre, Rio Grande do Sul, 90035-903, Brazil
Akero Clinical Study Site
Edmonton, Alberta, T6G 2X8, Canada
Akero Clinical Study Site
Toronto, Ontario, M5G 2C4, Canada
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Toronto, Ontario, M6H 3M1, Canada
Akero Clinical Study Site
Vaughan, Ontario, L4L 4Y7, Canada
Akero Clinical Study Site
Montreal, Quebec, H2X 0A9, Canada
Akero Clinical Study Site
Terrebonne, Quebec, J7B6B7, Canada
Akero Clinical Study Site
La Serena, Coquimbo Region, 1700000, Chile
Akero Clinical Study Site
Las Condes, Santiago Metropolitan, 7500000, Chile
Akero Clinical Study Site
Santiago, Santiago Metropolitan, 8320000, Chile
Akero Clinical Study Site
Santiago, Santiago Metropolitan, 8330109, Chile
Akero Clinical Study Site
Santiago, Santiago Metropolitan, 8380000, Chile
Akero Clinical Study Site
Strasbourg, Bas-Rhin, 67200, France
Akero Clinical Study Site
Limoges, Haute-Vienne, 87042, France
Akero Clinical Study Site
Lille, Hauts-de-France, 59037, France
Akero Clinical Study Site
Clichy, Hauts-de-Seine, 92118, France
Akero Clinical Study Site
Vandœuvre-lès-Nancy, Lorraine, 54511, France
Akero Clinical Study Site
Angers, Maine-et-Loire, 49933, France
Akero Clinical Study Site
Toulouse, Occitanie, 31059, France
Akero Clinical Study Site
Marseille, Provence-Alpes-Côte d'Azur Region, 13008, France
Akero Clinical Study Site
Montpellier Cedex 5, Provence-Alpes-Côte d'Azur Region, 34295, France
Akero Clinical Study Site
Nice, Provence-Alpes-Côte d'Azur Region, 06202, France
Akero Clinical Study Site
Lyon, Rhône, 69004, France
Akero Clinical Study Site
Créteil, Val-de-Marne, 94010, France
Akero Clinical Study Site
Le Chesnay, Île-de-France Region, 78150, France
Akero Clinical Study Site
Paris, Île-de-France Region, 75013, France
Akero Clinical Study Site
Frankfurt am Main, Hesse, 60590, Germany
Akero Clinical Study Site
Homburg, Saarland, 66421, Germany
Akero Clinical Study Site
Leipzig, Saxony, 04103, Germany
Akero Clinical Study Site
Leipzig, Saxony, 04103, Germany
Akero Clinical Study Site
Lübeck, Schleswig-Holstein, 23538, Germany
Akero Clinical Study Site
Berlin, State of Berlin, 13353, Germany
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Hyderabad, Andhra Pradesh, 500 082, India
Akero Clinical Study Site
Surat, Gujarat, 395002, India
Akero Clinical Study Site
Surat, Gujarat, 395009, India
Akero Clinical Study Site
Vadodara, Gujarat, 390007, India
Akero Clinical Study Site
Mysore, Karnataka, 570001, India
Akero Clinical Study Site
Thiruvananthapuram, Kerala, 695011, India
Akero Clinical Study Site
Mumbai, Maharashtra, 400008, India
Akero Clinical Study Site
Mumbai, Maharashtra, 400012, India
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Nagpur, Maharashtra, 440010, India
Akero Clinical Study Site
Pune, Maharashtra, 412201, India
Akero Clinical Study Site
New Delhi, National Capital Territory of Delhi, 110 070, India
Akero Clinical Study Site
New Delhi, National Capital Territory of Delhi, 110029, India
Akero Clinical Study Site
New Delhi, National Capital Territory of Delhi, 110060, India
Akero Clinical Study Site
Chandigarh, Punjab, 160012, India
Akero Clinical Study Site
Ludhiana, Punjab, 141002, India
Akero Clinical Study Site
Jaipur, Rajasthan, 302001, India
Akero Clinical Study Site
Jaipur, Rajasthan, 302001, India
Akero Clinical Study Site
Coimbatore, Tamil Nadu, 641005, India
Akero Clinical Study Site
Hyderabad, Telangana, 500 004, India
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Varanasi, Uttar Pradesh, 221005, India
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Varanasi, Uttar Pradesh, 221005, India
Akero Clinical Study Site
Rishikesh, Uttarakhand, 249203, India
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Kolkata, West Bengal, 700020, India
Akero Clinical Study Site
Kolkata, West Bengal, 700020, India
Akero Clinical Study Site
Kolkata, West Bengal, 700073, India
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Petah Tikva, Central District, 4941492, Israel
Akero Clinical Study Site
Ramat Gan, Central District, 5265601, Israel
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Haifa, Haifa District, 3109601, Israel
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Haifa, Haifa District, 3436212, Israel
Akero Clinical Study Site
Jerusalem, Jerusalem, 9103102, Israel
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Jerusalem, Jerusalem, 9112001, Israel
Akero Clinical Study Site
Afula, Northern District, 18101, Israel
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Nahariya, Northern District, 22100, Israel
Akero Clinical Study Site
Tel Aviv, Tel Aviv, 6423906, Israel
Akero Clinical Study Site
Tel Aviv, Tel Aviv, 69710, Israel
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Foggia, Apulia, 71122, Italy
Akero Clinical Study Site
San Giovanni Rotondo, Foggia, 71013, Italy
Akero Clinical Study Site
Messina, Messina, 98124, Italy
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Milan, Milan, 20122, Italy
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Milan, Milan, 20122, Italy
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Rozzano, Milan, 20089, Italy
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Novara, Novara, 28100, Italy
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Torino, Turin, 10126, Italy
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Bologna, 40138, Italy
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Catania, 95100, Italy
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Modena, 41124, Italy
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Acapulco de Juárez, Guerrero, 39670, Mexico
Akero Clinical Study Site
Guadalajara, Jalisco, 44130, Mexico
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Cuauhtémoc, Mexico City, 06700, Mexico
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Mexico City, Mexico City, 01376, Mexico
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Mérida, Yucatán, 97070, Mexico
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Benito Juárez, 3330, Mexico
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Mexico City, 14050, Mexico
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Poznan, Greater Poland Voivodeship, 61-293, Poland
Akero Clinical Study Site
Krakow, Lesser Poland Voivodeship, 31-501, Poland
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Wroclaw, Lower Silesian Voivodeship, 50-381, Poland
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Wroclaw, Lower Silesian Voivodeship, 53-673, Poland
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Lodz, Lódzkie, 91-473, Poland
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Warsaw, Masovian Voivodeship, 00-215, Poland
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Warsaw, Masovian Voivodeship, 02-672, Poland
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Gdansk, Pomeranian Voivodeship, Poland 80-382, Poland
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Częstochowa, Silesian Voivodeship, 42-202, Poland
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Katowice, Silesian Voivodeship, 40-752, Poland
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Manati, Manatí, 00674, Puerto Rico
Akero Clinical Study Site
Mayagüez, Puerto Rico, 00680, Puerto Rico
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San Juan, Puerto Rico, 00927, Puerto Rico
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Daegu, Daegu Gwang'Yeogsi [Taegu-Kwangyokshi], 41944, South Korea
Akero Clinical Study Site
Incheon, Gyeonggi-do, 22332, South Korea
Akero Clinical Study Site
Goyang-si, Gyeonggido, 10444, South Korea
Akero Clinical Study Site
Daegu, Gyeongsangbugdo [Kyongsangbuk-do], 42601, South Korea
Akero Clinical Study Site
Seoul, Seoul Teugbyeolsi [Seoul-T'Ukpyolshi], 03080, South Korea
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Seoul, Seoul Teugbyeolsi, 04763, South Korea
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Barcelona, Barcelona, 08035, Spain
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Sabadell, Barcelona, 08208, Spain
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Santander, Cantabria, 39008, Spain
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Madrid, Madrid, 28007, Spain
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Madrid, Madrid, 28027, Spain
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Majadahonda, Madrid, 28222, Spain
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Seville, Sevilla, 41013, Spain
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Valencia, Valencia, 46010, Spain
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Valencia, Valencia, 46015, Spain
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Bern, Canton of Bern, 3010, Switzerland
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Sankt Gallen, Canton of St. Gallen, 9007, Switzerland
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Zurich, Canton of Zurich, 8091, Switzerland
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Lugano, Canton Ticino, 6900, Switzerland
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Ankara, Ankara, 06560, Turkey (Türkiye)
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Bursa, Bursa, 16059, Turkey (Türkiye)
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Rize, Rize Province, 53020, Turkey (Türkiye)
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London, England, SE5 9RS, United Kingdom
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Nottingham, England, NG7 2UH, United Kingdom
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Birmingham, B15 2TH, United Kingdom
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London, NW3 2QG, United Kingdom
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London, SW10 9NH, United Kingdom
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Newcastle upon Tyne, NE7 7DN, United Kingdom
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Whitechapel, E1 1FR, United Kingdom
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- phase 3
- Allocation
- RANDOMIZED
- Masking
- QUADRUPLE
- Who Masked
- PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- INDUSTRY
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
June 28, 2024
First Posted
July 30, 2024
Study Start
September 4, 2024
Primary Completion (Estimated)
February 1, 2030
Study Completion (Estimated)
March 1, 2030
Last Updated
April 24, 2026
Record last verified: 2026-04