Key Insights

Highlights

Success Rate

83% trial completion

Published Results

25 trials with published results (21%)

Research Maturity

53 completed trials (44% of total)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 49/100

Termination Rate

9.1%

11 terminated out of 121 trials

Success Rate

82.8%

-3.7% vs benchmark

Late-Stage Pipeline

9%

11 trials in Phase 3/4

Results Transparency

47%

25 of 53 completed with results

Key Signals

25 with results83% success11 terminated

Data Visualizations

Phase Distribution

94Total
Not Applicable (30)
P 1 (21)
P 2 (32)
P 3 (7)
P 4 (4)

Trial Status

Completed53
Unknown21
Recruiting12
Active Not Recruiting12
Terminated11
Withdrawn6

Trial Success Rate

82.8%

Benchmark: 86.5%

Based on 53 completed trials

Clinical Trials (121)

Showing 20 of 20 trials
NCT03587831Not ApplicableRecruitingPrimary

Vertical Sleeve Gastrectomy and Lifestyle Modification for the Treatment of Non-Alcoholic Steatohepatitis

NCT06528314Phase 3RecruitingPrimary

A Study Evaluating Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASH

NCT05165446Active Not RecruitingPrimary

Novel MRE Technique to Assess a Risk Factor for Liver Cancer

NCT03472157Not ApplicableRecruiting

A Randomized Controlled Study Evaluating Bariatric Surgery as a Treatment for Severe NASH With Advanced Liver Fibrosis in Non-severe Obese Patients

NCT04383951Not ApplicableActive Not RecruitingPrimary

Safety and Efficacy of Ketogenic Diet for Promoting Weight Loss in Obese Individuals With Compensated NASH Cirrhosis

NCT06195943Not ApplicableCompletedPrimary

Feasibility, Safety and Acceptability of a Mobile Health Delivered Exercise Training Program in Patients With Nonalcoholic Steatohepatitis

NCT04849728Phase 3Active Not RecruitingPrimary

A Phase 3 Study Evaluating Efficacy and Safety of Lanifibranor Followed by an Active Treatment Extension in Adult Patients With (NASH) and Fibrosis Stages F2 and F3 ( NATiV3 )

NCT03468556Phase 2Not Yet RecruitingPrimary

A Randomized, Double-Blind, Placebo Controlled Study to Assess the Efficacy and Safety of SNP-610 for the Treatment of Patients With Non-alcoholic Steatohepatitis

NCT04591106Completed

Quantifying Body Composition and Liver Disease in Children Using Free-Breathing MRI and MRE

NCT04365868Phase 2Terminated

Study Evaluating the Efficacy and Safety of Belapectin for the Prevention of Esophageal Varices in NASH Cirrhosis

NCT02581085Phase 2Active Not Recruiting

Tocotrienol Against the Progression of End Stage Liver Disease

NCT04232566Recruiting

Investigating the Link Between Type 2 Immunity and NAFLD in Human Obesity

NCT04679376Phase 2Active Not RecruitingPrimary

Statins for the Treatment of NASH

NCT05023044Active Not Recruiting

Nonalcoholic Fatty Liver Disease in HIV Database

NCT03997422Not ApplicableActive Not RecruitingPrimary

Hepatic Energy Fluxes in NASH and NAS Patients

NCT04306939Suspended

Genomic Resources for Enhancing Available Therapies (GREAT1.0) Study

NCT04929483Phase 2CompletedPrimary

Study Evaluating the Safety, Efficacy and Tolerability of BIO89-100 in Subjects With Biopsy-confirmed Nonalcoholic Steatohepatitis (NASH)

NCT05364684Phase 2Completed

The Impact of Ibutamoren on Nonalcoholic Fatty Liver Disease

NCT04616664Completed

Diagnostic Accuracy of the "LLIFT", a Novel Non-invasive Biomarker for the Diagnosis of Non Alcoholic Fatty Liver (NAFL) and SteatoHepatitis (NASH) in a Population With High Risk of Metabolic Syndrome"

NCT04054310Not ApplicableRecruitingPrimary

Non-Invasive Quantification of Liver Health in NASH (N-QUAN)

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