Strength Training and Muscle Lipids
Strength-Lip
The Effects of Strength Training on Neuromuscular Function and Muscle Lipids.
1 other identifier
interventional
14
1 country
4
Brief Summary
The purpose of this study is examine the effects of 8 weeks (3 days/week) of resistance exercise training in children 8 to 10 years of age on muscle strength and power, motor unit activation, and lipid profiles of the vastus lateralis.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable healthy
Started Jul 2024
4 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
June 24, 2024
CompletedFirst Posted
Study publicly available on registry
June 28, 2024
CompletedStudy Start
First participant enrolled
July 1, 2024
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 7, 2024
CompletedStudy Completion
Last participant's last visit for all outcomes
December 7, 2024
CompletedAugust 20, 2025
August 1, 2025
5 months
June 24, 2024
August 14, 2025
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Change in muscular power of the leg extensors, as measured with isokinetic strength testing.
The score will reflect the muscular power of the leg extensors. The higher score, reflects greater muscular strength.
Baseline, following the intervention (9 weeks)
Secondary Outcomes (1)
Change from baseline in thigh muscle cross-sectional area
Baseline, following the intervention (9 weeks)
Other Outcomes (7)
Change from baseline in intramyocellular lipids of the vastus lateralis, as measure with magnetic resonance spectroscopy
baseline, following the intervention (9 weeks)
Change from baseline in extramyocellular lipids of the vastus lateralis, as measure with magnetic resonance spectroscopy
baseline, following the intervention (9 weeks)
Change from baseline in the fatty acid saturation levels of the extramyocellular lipids of the vastus lateralis, as measure with magnetic resonance spectroscopy
baseline, following the intervention (9 weeks)
- +4 more other outcomes
Study Arms (2)
Resistance exercise training
EXPERIMENTALControl
NO INTERVENTIONInterventions
Participants will strength train via linear periodization resistance exercise training.
Eligibility Criteria
You may qualify if:
- Healthy volunteer males and females ages 8 - 10 years.
You may not qualify if:
- No history or ongoing neuromuscular diseases.
- No history or ongoing musculoskeletal injuries.
- No history or ongoing disease that effects metabolism.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (4)
Hoglund Biomedical Imaging Center
Kansas City, Kansas, 66103, United States
Neuromechanics Laboratory
Lawrence, Kansas, 66045, United States
Exercise and Human Performance Laboratory
Overland Park, Kansas, 66213, United States
Metabolic and Body Composition Laboratory
Overland Park, Kansas, 66213, United States
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NON RANDOMIZED
- Masking
- NONE
- Purpose
- BASIC SCIENCE
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
June 24, 2024
First Posted
June 28, 2024
Study Start
July 1, 2024
Primary Completion
December 7, 2024
Study Completion
December 7, 2024
Last Updated
August 20, 2025
Record last verified: 2025-08
Data Sharing
- IPD Sharing
- Will not share