Comparing the Effects of Upper and Lower Body Resistance Training on Pain Sensitivity

NCT05985382 | Completed Results

• 1 other identifier: 5
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

Resistance exercise may immediately lessen the perception of pain. The purpose of this study is compare the effects of an upper body exercise to a lower body exercise on the perception of pain (pressure pain threshold).

Conditions

Healthy

Outcome Measures

Primary Outcomes (1)

• Lower Body Resistance Exercise

  For pressure pain threshold, an algometer was gradually increased until the sensation changed from pressure to pain. Pressure at threshold was recorded in kilopascals.

  Pressure pain threshold will be applied to the quadriceps immediately after each exercise.

Secondary Outcomes (1)

• Heat Pain Threshold

  Heat Pain Threshold will be applied over the quadriceps before and after the exercise.

Study Arms (2)

Lower Body Resistance Exercise

EXPERIMENTAL

Participants will perform a leg extension exercise with weight that is 75% of their estimated 1-repetition maximum (1-RM) for 3 sets of 10 repetitions.

Other: Lower Body Resistance Exercise

Upper Body Resistance Exercise

EXPERIMENTAL

Participants will perform a shoulder press with weight that is 75% of their estimated 1-repetition maximum (1-RM) for 3 sets of 10 repetitions.

Other: Upper Body Resistance Exercise

Interventions

Lower Body Resistance Exercise OTHER

Participants will complete a leg extension exercise with weight equivalent to 75% of their estimated 1-repetition maximum 3 sets, 10 repetitions.

Lower Body Resistance Exercise

Upper Body Resistance Exercise OTHER

Participants will complete a leg extension exercise with weight equivalent to 75% of their estimated 1-repetition maximum 3 sets, 10 repetitions.

Upper Body Resistance Exercise

Eligibility Criteria

• Age: 18 Years - 60 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• pain free

You may not qualify if:

• non-English speaking
• regular use of prescription pain medications
• current or history of chronic pain condition
• currently taking blood-thinning medication
• any blood clotting disorder
• medical conditions known to affect sensation, such as: uncontrolled diabetes or neurological conditions
• any contraindication to the application of ice, including: uncontrolled hypertension, cold urticaria, cryoglobulinemia, paroxysmal cold hemoglobinuria, circulatory compromise
• not physically ready to exercise without a medical exam as indicated by the Physical Activity Readiness Questionnaire Plus (PAR-Q+)
• surgery, injury, or fracture within the past 6 months
• unable to perform exercise portions of the study
• unable to attend three sessions
• pregnant

Sponsors & Collaborators

• University of Central Florida: lead

Study Sites (1)

University of Central Florida

Orlando, Florida, 32765, United States

Location

Results Point of Contact

• Title: Abigail Anderson
• Organization: University of Central Florida

Abigail.Wilson@ucf.edu

4078231026

Study Officials

• Abigail Wilson, PT, DPT, PhD

  University of Central Florida

  PRINCIPAL INVESTIGATOR

Publication Agreements

• PI is Sponsor Employee: No
• Restrictive Agreement: No

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: July 26, 2023
• First Posted: August 14, 2023
• Study Start: August 29, 2023
• Primary Completion: October 16, 2023
• Study Completion: October 16, 2023
• Last Updated: March 4, 2025
• Results First Posted: March 4, 2025

Record last verified: 2025-02

Locations

US (1)