The Effects of L-arginine Supplementation on Anaerobic Exercise Performance

NCT06475391 | Recruiting

• 1 other identifier: HE2024-0063
• Study Type: interventional
• Target: 20
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to evaluate if acute ingestion of L-arginine will enhance anaerobic exercise performance in young, healthy, and recreationally active adults.

Conditions

Skeletal Muscle; Human Performance

Outcome Measures

Primary Outcomes (3)

• Grip Strength

  Grip strength measurement in kilograms of force produced on a hand held dynamometer.

  5 minutes

• Counter movement vertical jump

  Counter movement vertical jump performance height in centimeters.

  3 minutes

• Wingate anaerobic cycle ergometer test

  Maximum pedaling power output for 30 seconds of all-out sprinting on a cycle ergometer.

  30 seconds

Study Arms (2)

L-arginine

EXPERIMENTAL

Participants will ingest 2 grams of L-arginine before completing three anaerobic exercise tasks (grip strength, vertical jump, and Wingate cycle ergometer test).

Dietary Supplement: L-arginine

Placebo

PLACEBO COMPARATOR

Participants will ingest 2 grams of placebo (dextrose) before completing three anaerobic exercise tasks (grip strength, vertical jump, and Wingate cycle ergometer test).

Dietary Supplement: Placebo

Interventions

L-arginine DIETARY_SUPPLEMENT

2 grams iof L-arginine will be ingested before an acute testing bout of exercise tasks in 250 mL of cranberry juice.

L-arginine

Placebo DIETARY_SUPPLEMENT

Placebo

Placebo

Eligibility Criteria

• Age: 18 Years - 39 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Recreationally physically active individuals will be recruited for the study. In this context it means all participants perform 1-hour of exercise per day over 3-days per week at a minimum for 1-month. All participants will be between the ages of 18-39 years of age.

Sponsors & Collaborators

• University of Manitoba: lead

Study Sites (1)

Applied Research Centre; Active Living Centre

Winnipeg, Manitoba, R3T 2N2, Canada

RECRUITING

MeSH Terms

Interventions

Arginine

Intervention Hierarchy (Ancestors)

Amino Acids, Basic; Amino Acids; Amino Acids, Peptides, and Proteins; Amino Acids, Diamino; Amino Acids, Essential

Central Study Contacts

Stephen M Cornish, PhD

CONTACT

204-381-7296; Stephen.Cornish@umanitoba.ca

Mikal Thrones, BSc

CONTACT

thronesm@myumanitoba.ca

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: TRIPLE
• Who Masked: PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
• Purpose: BASIC SCIENCE
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 20, 2024
• First Posted: June 26, 2024
• Study Start: June 14, 2024
• Primary Completion: September 1, 2024
• Study Completion: December 31, 2024
• Last Updated: June 26, 2024

Record last verified: 2024-06

Data Sharing

• IPD Sharing: Will not share

Locations

CA (1)