NCT02919254

Brief Summary

The purpose of this study is to examine the effect of varying nitrate doses of beetroot juice supplementation on dynamic, multijoint resistance exercise performance in active, trained individuals. Performance will be assessed based on parameters including neuromuscular efficiency, anaerobic performance capability, oxygen consumption, plasma nitrate/nitrite levels, specific muscle tissue biomarkers including lactate, and anthropometric measurements of select muscle groups.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
13

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Aug 2016

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 1, 2016

Completed
4 days until next milestone

First Submitted

Initial submission to the registry

August 5, 2016

Completed
2 months until next milestone

First Posted

Study publicly available on registry

September 29, 2016

Completed
7 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2017

Completed
1.6 years until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2018

Completed
Last Updated

January 31, 2020

Status Verified

January 1, 2020

Enrollment Period

9 months

First QC Date

August 5, 2016

Last Update Submit

January 29, 2020

Conditions

Outcome Measures

Primary Outcomes (1)

  • Muscle activation and fiber recruitment

    Muscle activation/fiber recruitment to be measured in millivolts (mV) using electromyography (EMG) sensor during maximum voluntary contractions (MVC) and compared between study arms.

    5 weeks

Secondary Outcomes (3)

  • Plasma nitrate/nitrite levels

    5 weeks

  • Number of repetitions performed

    5 weeks

  • Oxygen consumption

    5 weeks

Study Arms (3)

High Dosage

ACTIVE COMPARATOR

Subjects will receive approximately 8 mmol of dietary nitrate per day delivered as a commercially available beetroot juice supplement for 7 days.

Dietary Supplement: Beet It Sport Shot

Moderate Dosage

ACTIVE COMPARATOR

Subjects will receive approximately 0.5 mmol of dietary nitrate per day delivered as a commercially available beetroot juice supplement for 7 days.

Dietary Supplement: Beet It Sport Shot

Placebo

PLACEBO COMPARATOR

Subjects will receive a placebo beverage containing negligible nitrate for 7 days.

Other: Placebo

Interventions

Beet It Sport ShotDIETARY_SUPPLEMENT

Commercially available concentrated beetroot juice supplement intended for athletes.

High DosageModerate Dosage
PlaceboOTHER

Fruit juice cordial containing negligible nitrate

Placebo

Eligibility Criteria

Age18 Years - 35 Years
Sexmale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Minimum 6 consecutive months experience in resistance training, engaging at least 2 times per week.
  • Possess sufficient mobility to properly execute movements required in testing protocol

You may not qualify if:

  • Usage of any banned dietary supplements or performance enhancing drugs (thermogenics, anabolic steroids, prohormones, etc.)
  • Any physical condition or malady that would impede participant from performing exercise or by doing so, endanger the individual

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Richardson Centre for Functional Foods and Nutraceuticals

Winnipeg, Manitoba, R3T 6C5, Canada

Location

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, INVESTIGATOR
Purpose
BASIC SCIENCE
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Dr. Semone Myrie

Study Record Dates

First Submitted

August 5, 2016

First Posted

September 29, 2016

Study Start

August 1, 2016

Primary Completion

May 1, 2017

Study Completion

December 1, 2018

Last Updated

January 31, 2020

Record last verified: 2020-01

Data Sharing

IPD Sharing
Will not share

Locations