The Effect of Acute Concurrent Exercise on Inhibitory Control: An Event-related Potential Study

NCT06370286 | Completed

• 1 other identifier: PACNL_rueihongli_CE_IC
• Study Type: interventional
• Target: 78
• Locations: 1 country
• Sites: 1

Brief Summary

The present study aimed to determine the effects of acute concurrent exercise on inhibitory control via behavioral and event-related potential approaches and to examine its potential mediational role on lactate among younger adults. The main questions it aims to answer are: (1) Does acute concurrent exercise improve inhibitory control via behavioral and event-related potential approaches? (2) Does lactate play a potential mediational role in the effect of acute concurrent exercise on inhibitory control?

Conditions

Exercise; Cognition

Outcome Measures

Primary Outcomes (1)

• Inhibitory control

  Inhibitory control was assessed using a modified computerized version of the Stroop test, which was administered through Neuroscan Stim2 software (Compumedics Neuroscan, Charlotte, NC). The test comprised four blocks, each consisting of 108 trials. Within each block, three types of trials were presented: neutral, congruent, and incongruent. The neutral trial involved displaying a square printed in red, green, or blue color. The congruent trial presented Chinese language prints in corresponding colors and words \[i.e., 紅 (RED), 綠 (GREEN), or 藍 (BLUE)\]. In contrast, the incongruent trial displayed Chinese language prints in different colors and words \[e.g., 紅 (RED) printed in blue color\]. Each block included 36 neutral trials, 36 congruent trials, and 36 incongruent trials. Participants were instructed to respond promptly and accurately to the color of the stimulus presented. Subsequently, the mean response time (RT) of correct trials and accuracy for each Stroop condition were examined.

  30 minutes

Secondary Outcomes (1)

• Blood lactate

  Timepoint 1 (prior to the commencement of treatment), Timepoint 2 (17 minutes after the initiation of treatment), and Timepoint 3 (30 minutes after the start of treatment).

Study Arms (3)

concurrent exercise (CE)

EXPERIMENTAL

Participants in the concurrent exercise group engaged in 12-minutes of aerobic exercise (40%-59% of heart rate reserve \[HRR\]) coupled with 13-minutes of resistance exercise (1 set, with 75% of 10-repetition maximum, and 12 repetitions of 8 movements). Prior to and following exercise onset, participants completed a 5-minute warm-up and cool-down.

Behavioral: concurrent exercise (CE)

aerobic exercise (AE)

EXPERIMENTAL

Participants in the aerobic exercise (AE) group participated in 25 minutes of AE (40%-59% of heart rate reserve \[HRR\]). Prior to and following exercise onset, participants completed a 5-minute warm-up and cool-down.

Behavioral: aerobic exercise (AE)

control (CON)

NO INTERVENTION

Participants in the control group read books for 35 minutes.

Interventions

concurrent exercise (CE) BEHAVIORAL

Participants in the concurrent exercise group engaged in 12-minutes of aerobic exercise (40%-59% of heart rate reserve \[HRR\]) coupled with 13-minutes of resistance exercise (1 set, with 75% of 10-repetition maximum, and 12 repetitions of 8 movements). Prior to and following exercise onset, participants completed a 5-minute warm-up and cool-down.

concurrent exercise (CE)

aerobic exercise (AE) BEHAVIORAL

Participants in the aerobic exercise (AE) group participated in 25 minutes of AE (40%-59% of heart rate reserve \[HRR\]). Prior to and following exercise onset, participants completed a 5-minute warm-up and cool-down.

aerobic exercise (AE)

Eligibility Criteria

• Age: 20 Years - 30 Years
• Gender Eligibility Details: Participant eligibility is based on self-representation of gender identity.
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• aged between 20 and 30 years
• able to exercise without undue risk (i.e., the first seven questions of the Physical Activity Readiness Questionnaire for Everyone \[PAR-Q+\] were answered "No")
• right-handed dominance
• typical or corrected-to-typical eyesight
• limited physical activity in the previous month (i.e., \< 150 minutes/week of moderate-intensity physical activity)

You may not qualify if:

• psychiatric or neurological ailments
• cardiorespiratory or neuromuscular conditions
• obese status (body mass index \[BMI\] \> 27 kg/m2)

Sponsors & Collaborators

• National Taiwan Normal University: lead

Study Sites (1)

Department of Physical Education and Sport Sciences, National Taiwan Normal University

Taipei, 106, Taiwan

Location

Related Publications (1)

• Li RH, Chen TR, Gilson ND, Brazaitis M, Cheng YT, Wu HF, Lee JH, Chang YK. Acute Concurrent Exercise Improves Inhibitory Control Without Mediating the Role of Lactate: An Event-Related Potential Study. Sports Med Open. 2025 Jan 27;11(1):12. doi: 10.1186/s40798-024-00809-2.

  PMID: 39871026 DERIVED

MeSH Terms

Conditions

Motor Activity

Interventions

Exercise

Condition Hierarchy (Ancestors)

Behavior

Intervention Hierarchy (Ancestors)

Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Officials

• Yu-Kai Chang, PhD

  Department of Physical Education and Sport Sciences, National Taiwan Normal University

  STUDY CHAIR

• Ruei-Hong Li, MS

  Department of Physical Education and Sport Sciences, National Taiwan Normal University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: Participants were randomly assigned to either a concurrent exercise (CE), aerobic exercise (AE), or control (CON) group. Participants in the CE group engaged in 12-minutes of AE (40%-59% of heart rate reserve \[HRR\]) coupled with 13-minutes of resistance exercise (1 set, with 75% of 10-repetition maximum, and 12 repetitions of 8 movements). The AE group participated in 25 minutes of AE (40%-59% HRR). Prior to and following exercise onset, participants in both the CE and AE groups completed a 5-minute warm-up and cool-down. Participants in the CON group read books for 35 minutes. Lactate concentrations were measured at timepoint of 0-, 17-, and 30-minutes relative to the treatment onset. Response time (RT) and accuracy in the Stroop test, as well as P3 amplitudes, were assessed before and after the treatment.

Study Record Dates

• First Submitted: April 12, 2024
• First Posted: April 17, 2024
• Study Start: February 15, 2021
• Primary Completion: August 15, 2021
• Study Completion: February 15, 2022
• Last Updated: April 18, 2024

Record last verified: 2024-04

Locations

TW (1)