NCT05311202

Brief Summary

The current study is a five-arm, single bout program aiming to assess the effects of training volume and intensity of acute resistance exercise on inhibitory control on neurocognitive function with respect to event-related potential in adults aged 20 - 26 years.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
175

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Apr 2022

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 16, 2022

Completed
16 days until next milestone

Study Start

First participant enrolled

April 1, 2022

Completed
4 days until next milestone

First Posted

Study publicly available on registry

April 5, 2022

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 30, 2022

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2022

Completed
Last Updated

May 13, 2022

Status Verified

May 1, 2022

Enrollment Period

6 months

First QC Date

March 16, 2022

Last Update Submit

May 9, 2022

Conditions

Keywords

Acute resistance exerciseInhibitory controlTraining volumeIntensityEvent-related potential

Outcome Measures

Primary Outcomes (2)

  • Changes In Inhibitory Control

    The computerized Stroop test will be administrated to assess participants' inhibitory function, and the changes in Emotional Stroop test performance (i.e., response time and accuracy) before (pre-test) and after (post-test) intervention will be examined.

    30 minutes each before & after intervention

  • Changes In Neuroelectrical Activities: Event-Related Potential Recording and Analysis

    The continuous electroencephalogram (EEG) activity of each participant will be recorded throughout the entire Stroop task using a Neuroscan Quick-Cap, with 32 Ag/AgCl electrodes arranged following the international 10-20 system (NeuroScan Inc., El Paso, TX, USA). Changes in the neuroelectrical activities before and after the intervention will be examined. The time windows for each ERP component will be determined based on a visual inspection of the averaged grand waveform.

    30 minutes each before & after intervention

Secondary Outcomes (6)

  • Changes In Positive & Negative Affect

    5 minutes after pre-test and post-test of Stroop test

  • Muscular Fitness Measurements (1RM)-Deadlift

    2 hours on the first day

  • Muscular Fitness Measurements (1RM)-Bench Press

    2 hours on the first day

  • Muscular Fitness Measurements (1RM)-Squat

    2 hours on the first day

  • Muscular Fitness Measurements (1RM)-Rowing

    2 hours on the first day

  • +1 more secondary outcomes

Study Arms (5)

low-volume moderate-intensity group

EXPERIMENTAL

Participants will attend the trainer-supervised resistance exercise program for 30 minutes

Behavioral: low-volume moderate-intensity group

moderate-volume moderate-intensity group

EXPERIMENTAL

Participants will attend the trainer-supervised resistance exercise program for 40 minutes

Behavioral: moderate-volume moderate-intensity group

high-volume moderate-intensity group

EXPERIMENTAL

Participants will attend the trainer-supervised resistance exercise program for 50 minutes

Behavioral: high-volume moderate-intensity group

moderate-volume low-intensity group

EXPERIMENTAL

Participants will attend the trainer-supervised resistance exercise program for 45 minutes

Behavioral: moderate-volume low-intensity group

Control group

EXPERIMENTAL

Reading for 40 minutes

Behavioral: Control group

Interventions

The interventional program will include (1) 5 minutes of warm-up and aerobic exercise from light to moderate intensity; (2) 20 minutes of two sets of moderate intensity resistance exercise with 10 repetitions; (3) 5 minutes of cool down

low-volume moderate-intensity group

The interventional program will include (1) 5 minutes of warm-up and aerobic exercise from light to moderate intensity; (2) 30 minutes of three sets of moderate intensity resistance exercise with 10 repetitions; (3) 5 minutes of cool down

moderate-volume moderate-intensity group

The interventional program will include (1) 5 minutes of warm-up and aerobic exercise from light to moderate intensity; (2) 40 minutes of four sets of moderate intensity resistance exercise with 10 repetitions; (3) 5 minutes of cool down

high-volume moderate-intensity group

The interventional program will include (1) 5 minutes of warm-up and aerobic exercise from light to moderate intensity; (2) 35 minutes of four sets of low intensity resistance exercise with 20 repetitions; (3) 5 minutes of cool down

moderate-volume low-intensity group
Control groupBEHAVIORAL

Reading a book related to cognitive function \& exercise for 40 minutes

Control group

Eligibility Criteria

Age20 Years - 26 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • The dominant hand is right-handed
  • \< BMI \< 26
  • Can cooperate with fingertip blood collection
  • No color blindness and epilepsy
  • Not taking medications that affect brain function
  • Irregular exercise (more than 150 minutes per week for 3 months)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

National Taiwan Normal University

Taipei, 106, Taiwan

RECRUITING

Related Publications (1)

  • Chen YC, Lo YH, Hung CS, Cheng YT, Li RH, Chen FT, Chang YK. Acute effects of resistance exercise intensity and repetition at a predetermined volume on inhibitory control: a randomized controlled trial. Front Sports Act Living. 2025 Mar 13;7:1551624. doi: 10.3389/fspor.2025.1551624. eCollection 2025.

MeSH Terms

Conditions

Motor Activity

Interventions

Control Groups

Condition Hierarchy (Ancestors)

Behavior

Intervention Hierarchy (Ancestors)

Epidemiologic Research DesignEpidemiologic MethodsInvestigative TechniquesResearch DesignMethods

Study Officials

  • Yu-Kai Chang, Ph.D.

    Department of Physical Education and Sport Sciences, National Taiwan Normal University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Yu-Kai Chang, Ph.D

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
HEALTH SERVICES RESEARCH
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Research Chair professor

Study Record Dates

First Submitted

March 16, 2022

First Posted

April 5, 2022

Study Start

April 1, 2022

Primary Completion

September 30, 2022

Study Completion

December 31, 2022

Last Updated

May 13, 2022

Record last verified: 2022-05

Data Sharing

IPD Sharing
Will not share

Locations