NCT06300242

Brief Summary

In this work, we are assessing the impact of messaging with or without a $50 financial incentive on influenza vaccination rates in a county health system. Our main hypothesis is that a message with a $50 financial incentive will increase vaccination rates relative to a control/"treatment as usual" group. We further hypothesize that the financial incentive will increase vaccination rates relative to the message only arm.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
69,972

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Jan 2024

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 17, 2024

Completed
7 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 24, 2024

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

February 28, 2024

Completed
1 day until next milestone

Study Completion

Last participant's last visit for all outcomes

February 29, 2024

Completed
8 days until next milestone

First Posted

Study publicly available on registry

March 8, 2024

Completed
Last Updated

May 13, 2024

Status Verified

May 1, 2024

Enrollment Period

7 days

First QC Date

February 28, 2024

Last Update Submit

May 9, 2024

Conditions

Outcome Measures

Primary Outcomes (1)

  • Vaccination status at 1 week

    influenza vaccination status as documented in the EMR and from the California Immunization Registry (CAIRS)

    1 week

Secondary Outcomes (2)

  • Vaccination status at 2 weeks

    2 weeks

  • Vaccination status at 1 month

    1 month

Study Arms (3)

Message Only

EXPERIMENTAL

Patients sent an email or SMS reminding them to get vaccinated against the flu.

Behavioral: Reminders

Message + Financial Incentive

EXPERIMENTAL

Patients sent an email or SMS reminding them to get vaccinated against the flu and offering them a $50 financial incentive if they are vaccinated within 1-week.

Behavioral: RemindersBehavioral: Financial Incentive

Active Control

ACTIVE COMPARATOR

Patients not sent any reminder message.

Other: Placebo

Interventions

RemindersBEHAVIORAL

Reminders

Message + Financial IncentiveMessage Only

$50 financial incentive for getting vaccinated within 1-week

Message + Financial Incentive
PlaceboOTHER

No special messages or incentives

Active Control

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Ages 18 and over
  • Empaneled patients or non-empaneled patients with a primary care visit in past 18 months with valid insurance
  • Due for an annual flu shot according to the electronic medical record
  • Active phone number or email
  • Do not have "Do not contact" flag

You may not qualify if:

  • Under age 18
  • Received an annual flu shot based on medical record

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Contra Costa Health Services

Martinez, California, 94553, United States

Location

Related Publications (1)

  • Chang TY, Jacobson M, Shah M, Pramanik R, Shah SB. Impact of reminder messages, with and without financial incentives, on influenza vaccination: A randomized trial in a California health system. Vaccine. 2026 Jan 27;75:128263. doi: 10.1016/j.vaccine.2026.128263. Online ahead of print.

MeSH Terms

Conditions

Influenza, Human

Condition Hierarchy (Ancestors)

Respiratory Tract InfectionsInfectionsOrthomyxoviridae InfectionsRNA Virus InfectionsVirus DiseasesRespiratory Tract Diseases

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
HEALTH SERVICES RESEARCH
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor

Study Record Dates

First Submitted

February 28, 2024

First Posted

March 8, 2024

Study Start

January 17, 2024

Primary Completion

January 24, 2024

Study Completion

February 29, 2024

Last Updated

May 13, 2024

Record last verified: 2024-05

Data Sharing

IPD Sharing
Will share

Will be shared with qualified researchers upon request.

Shared Documents
STUDY PROTOCOL, SAP, ANALYTIC CODE

Locations