OPERATION WIPE OUT: Multi-Channel Communication Campaign to Promote HPV Vaccination in Chambers County, Alabama

NCT06247124 | Active Not Recruiting

• 2 other identifiers: IRB3000011735P30CA013148
• Study Type: interventional
• Target: 29
• Locations: 1 country
• Sites: 1

Brief Summary

The Advisory Committee on Immunization Practices (ACIP) recommends HPV vaccination for all children and adults ages 9 to 26 in the U.S. However, HPV vaccination rates nationally and in Alabama lag far behind the Healthy People 2020 goal of 80% coverage. Despite multiple efforts, Alabama still ranks third in cervical cancer mortality and incidence nationally with great disparities within the state, particularly between urban and rural counties. In order to address this public health challenge, organizations have come together to develop, implement, and evaluate a statewide action plan to eliminate cervical cancer as a public health problem in Alabama by 2033. This plan was officially launched by the State Health Officer in May 2023 as a partnership between government, academia, civic organizations, and non-profit organizations and is known as OPERATION WIPE OUT. The overall goal of this Supplement is to develop, implement, and examine the feasibility and scalability of a theory-driven, participatory multi-channel communication campaign to promote HPV vaccination uptake that is designed and delivered by high school students with the support of OPERATION WIPE OUT partners and linked to school-based vaccination in a rural county that has the highest cervical cancer incidence in the state (Chambers County). The specific aims are: (1) To develop and examine the feasibility of a theory-driven, participatory multi-channel communication campaign to promote HPV vaccination uptake with high school students being agents of change and provision of school-based vaccination; and (2) To examine specific features of the multi-channel communication campaign regarding scalability, sustainability, and potentially a future full-scale implementation science trial. The primary outcome will be HPV vaccination uptake at the county level obtained Alabama Department of Public Health Vaccination Registry (ImmPRINT). Additionally, treatment fidelity and scalability assessments will be conducted to inform sustainability efforts.

Conditions

HPV Vaccination

Keywords

HPV vaccination; Schools; High school students

Outcome Measures

Primary Outcomes (1)

• HPV Vaccination at the county level

  HPV vaccination uptake at the county level

  One year

Secondary Outcomes (1)

• HPV vaccination at the school level

  one year

Other Outcomes (1)

• Knowledge and confidence among the high school students

  6 months

Study Arms (1)

HPV vaccination

OTHER

Multi-channel campaign to promote HPV vaccination

Behavioral: multi-channel communication campaign to promote HPV vaccination

Interventions

multi-channel communication campaign to promote HPV vaccination BEHAVIORAL

High school students will develop, implement, and evaluate a multi-channel communication campaign to promote HPV vaccination.

HPV vaccination

Eligibility Criteria

• Age: 15 Years - 18 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64)

You may qualify if:

• High school students enrolled in the Health Science Program at the Chambers County School District, Alabama

Sponsors & Collaborators

• University of Alabama at Birmingham: lead

Study Sites (1)

Chambers County School District

Lafayette, Alabama, 36862, United States

Location

Study Officials

• Isabel Scarinci, PhD

  University of Alabama at Birmingham

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Model Details: high school students are enrolled as research participants to develop a multi-channel campaign to promote HPV vaccination

Study Record Dates

• First Submitted: January 30, 2024
• First Posted: February 7, 2024
• Study Start: November 1, 2023
• Primary Completion: March 31, 2026
• Study Completion: March 31, 2026
• Last Updated: February 9, 2026

Record last verified: 2026-02

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)