NCT06224933

Brief Summary

The purpose of this study is to determine feasibility and safety of using an augmented reality system in patients undergoing MRI-Guided needle procedures.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
25

participants targeted

Target at below P25 for not_applicable

Timeline
1mo left

Started Feb 2024

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress97%
Feb 2024May 2026

First Submitted

Initial submission to the registry

November 22, 2023

Completed
2 months until next milestone

First Posted

Study publicly available on registry

January 25, 2024

Completed
12 days until next milestone

Study Start

First participant enrolled

February 6, 2024

Completed
2.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 31, 2026

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 31, 2026

Last Updated

September 5, 2025

Status Verified

August 1, 2025

Enrollment Period

2.3 years

First QC Date

November 22, 2023

Last Update Submit

August 28, 2025

Conditions

Outcome Measures

Primary Outcomes (2)

  • Feasibility is measured by successful completion of greater than 80% of cases using the augmented reality needle guidance system.

    1 day

  • Safety of using the augmented reality needle guidance system will be evaluated through assessment of procedure related adverse events that occur within 7 days of the procedure.

    7 days

Secondary Outcomes (3)

  • Procedure time

    1 day

  • Number of MRI scans

    1 day

  • Clinical impressions of the system use and utility

    1 Day

Study Arms (1)

Patients Undergoing Augmented Reality Image-Guided Needle Procedures

EXPERIMENTAL

Patients will undergo their standard of care image-guided needle biopsy, aspiration, or injection with the Augmented Reality system. Patients will be monitored for adverse events for two weeks following their procedure.

Device: Augmented Reality System

Interventions

Subjects will undergo image guided needle aspiration, injection, or biopsy facilitated by the Augmented Reality system. The Augmented Reality guidance system will be operated by the interventional radiologist in the MRI suite.

Patients Undergoing Augmented Reality Image-Guided Needle Procedures

Eligibility Criteria

Age3 Years - 21 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • Provision of signed and dated informed consent form
  • Stated willingness to comply with all study procedures and availability for the duration of the study
  • Male or female, ages 3 to 21
  • Patient referred to Interventional Radiology for image-guided needle injection, aspiration, or biopsy.

You may not qualify if:

  • Patients who are unable to give informed consent themselves or through their parents.
  • Patients under 3 years of age
  • Patients over 300 pounds.
  • Patients who are claustrophobic and unable to tolerate MRI-guided procedure.
  • Contraindications to MRI such as MR-unsafe implants.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Children's National Hospital

Washington D.C., District of Columbia, 20010, United States

RECRUITING

MeSH Terms

Conditions

InfectionsPainDisease

Condition Hierarchy (Ancestors)

Neurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and SymptomsPathologic Processes

Study Officials

  • Karun Sharma, MD, PhD

    Children's National Research Institute

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
DEVICE FEASIBILITY
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Director of Interventional Radiology

Study Record Dates

First Submitted

November 22, 2023

First Posted

January 25, 2024

Study Start

February 6, 2024

Primary Completion (Estimated)

May 31, 2026

Study Completion (Estimated)

May 31, 2026

Last Updated

September 5, 2025

Record last verified: 2025-08

Locations