NCT06112626

Brief Summary

Chlorhexidine gluconate (CHG) bathing is an effective intervention to reduce hospitalized patient's risk of acquiring a central line-associated bloodstream infection (CLABSI). While daily CHG bathing for hospitalized patients is widely supported in the literature, patient adherence with this practice is suboptimal. Written and verbal information is provided to patients by nursing staff regarding the importance of CHG bathing and the correct usage of the CHG cloths; however, these methods can be hindered by literacy and language barriers. Medical videos have become popular avenues to provide necessary education to patients, and have been shown to improve patient-reported outcomes. Whereas the benefits of educational videos has been described in previous studies on advanced care planning and postoperative quality of life, they have not been described for CHG bathing. In this study, we aim to provide education (including the rationale/importance of CHG bathing, and the appropriate process for bathing) through the use of a short video provided to hospitalized patients. The purpose of this study is to evaluate the use of medical videos to educate patients on CHG bathing while hospitalized in the inpatient setting.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,000

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started May 2024

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

October 10, 2023

Completed
22 days until next milestone

First Posted

Study publicly available on registry

November 1, 2023

Completed
6 months until next milestone

Study Start

First participant enrolled

May 1, 2024

Completed
1.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 30, 2025

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 30, 2025

Completed
Last Updated

October 15, 2025

Status Verified

October 1, 2025

Enrollment Period

1.4 years

First QC Date

October 10, 2023

Last Update Submit

October 13, 2025

Conditions

Infections

Outcome Measures

Primary Outcomes (1)

  • Percentage of patients with a documented chlorhexidine gluconate bath documentation compliance

    Compliance with documenting CHG bath treatment in the electronic health record; measured via a report from the electronic health record

    Up to 12 months

Secondary Outcomes (3)

  • Rate of central line associated bloodstream infections per 1000 central line days

    Up to 12 months

  • Patient use of CHG skin treatment video

    4 weeks

  • Patient-centered outcome questionnaire

    4 weeks

Study Arms (2)

Intervention Group

EXPERIMENTAL

Intervention Group: In addition to the current educational document available for CHG bathing, patients in the intervention group would be provided access to a CHG bathing video through multiple avenues (QR codes placed in the room/unit, video provided on unit iPads). Nurses will be instructed to provide QR codes to patients to scan and watch the video. Patients can scan the QR code using their own smart device or through unit-based iPads. After viewing the video, there is another QR code to scan that goes to a short patient survey.

Behavioral: CHG Skin Treatment Video

Control Group

NO INTERVENTION

Control Group: Patients in the control group would have access to the current education available (patient education document) - usual care

Interventions

CHG Skin Treatment VideoBEHAVIORAL

Short CHG skin treatment video that reviews the rationale/importance of CHG bathing, and the appropriate process for bathing

Intervention Group

Eligibility Criteria

Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Patients admitted to an intervention unit who require a CHG skin treatment

You may not qualify if:

  • CHG allergy
  • Patients on comfort care

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Duke University Hospital

Durham, North Carolina, 27710, United States

Location

WakeMed Health and Hospitals

Raleigh, North Carolina, 27610, United States

Location

MeSH Terms

Conditions

Infections

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
HEALTH SERVICES RESEARCH
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 10, 2023

First Posted

November 1, 2023

Study Start

May 1, 2024

Primary Completion

September 30, 2025

Study Completion

September 30, 2025

Last Updated

October 15, 2025

Record last verified: 2025-10

Data Sharing

IPD Sharing
Will not share

Locations

US(2)