NCT06171009

Brief Summary

This is a single-site, two-arm, parallel-group randomized clinical trial (RCT). The analgesic effects of a 4-minute audio-recorded mindfulness intervention for orthopedic patients will be investigated relative to a 4-minute audio-recoding about pain psychoeducation. Analgesic mechanisms of mindfulness will also be investigated.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
158

participants targeted

Target at P75+ for not_applicable pain

Timeline
Completed

Started May 2024

Shorter than P25 for not_applicable pain

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

December 6, 2023

Completed
8 days until next milestone

First Posted

Study publicly available on registry

December 14, 2023

Completed
5 months until next milestone

Study Start

First participant enrolled

May 15, 2024

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 18, 2024

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 18, 2024

Completed
Last Updated

September 19, 2024

Status Verified

September 1, 2024

Enrollment Period

1 month

First QC Date

December 6, 2023

Last Update Submit

September 5, 2024

Conditions

Outcome Measures

Primary Outcomes (1)

  • Change in Pain Unpleasantness Numeric Rating Scale

    Single Likert scale item ranging from 0-10, with 0 indicating no pain and 10 representing the most unpleasant pain imaginable.

    Immediately before to after 4-minute audio recording

Secondary Outcomes (3)

  • Change in Pain Intensity Numeric Rating Scale

    Immediately before to after 4-minute audio recording

  • Change in Decentering

    Immediately before to after 4-minute audio recording

  • Change in Self-Transcendent State

    Immediately before to after 4-minute audio recording

Study Arms (2)

Pain Coping Information

ACTIVE COMPARATOR
Behavioral: Pain Coping Information

Mindful Pain Management

EXPERIMENTAL
Behavioral: Mindful Pain Management

Interventions

A 4-minute audio recording providing common pain coping techniques (e.g., ice, rest, medication, surgery).

Pain Coping Information

A 4-minute audio recording consisting of a 1-minute introduction to mindfulness followed by a 1-minute and 30-second mindful breathing practice and a 1-minute and 30-second mindfulness of pain practice.

Mindful Pain Management

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Age ≥18
  • Seeking treatment at the Tallahassee Orthopedic Center

You may not qualify if:

  • Cognitive impairment preventing completion of study procedures.
  • Other unstable illness judged by medical staff to interfere with study involvement.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Tallahassee Orthopedic Clinic (TOC)

Tallahassee, Florida, 32308, United States

Location

Related Publications (1)

  • Hanley AW, Gibson R, Davis A, Stecher C, Childs K, Worts P. Mindfulness in the Orthopedic Clinic Waiting Room Decreases Pain: Results From A Randomized Controlled Trial. Int J Behav Med. 2025 Nov 10. doi: 10.1007/s12529-025-10398-3. Online ahead of print.

MeSH Terms

Conditions

Pain

Condition Hierarchy (Ancestors)

Neurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
TRIPLE
Who Masked
PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor

Study Record Dates

First Submitted

December 6, 2023

First Posted

December 14, 2023

Study Start

May 15, 2024

Primary Completion

June 18, 2024

Study Completion

June 18, 2024

Last Updated

September 19, 2024

Record last verified: 2024-09

Locations