Interference of Endurance Training on Strength Development and Neuromuscular Adaptations

NCT06378762 | Active Not Recruiting DMC

• 1 other identifier: 6/2021
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

This study aims to find out if performing combined strength and endurance exercise in the same program (called concurrent training-CT) leads to similar long-term improvements in neuromuscular function as doing each type of exercise separately. The main questions it seeks to answer are: Does performing CT result in similar improvements in strength and power as doing just strength training? Does performing CT result in similar improvements in cardiorespiratory fitness as doing just endurance training? Are neuromuscular adaptations similar between CT and just strength training? Researchers will compare the results between three groups: the CT group, the endurance training group (E), and the strength training group (S) to answer these questions.

Conditions

Exercise

Keywords

Neuromuscular adaptations; Concurrent training; Interference effect; Endurance; Strength

Outcome Measures

Primary Outcomes (9)

• Maximal Isometric Strength

  Maximal voluntary isometric strength of the plantarflexors and leg press exercise in Newtons

  Baseline, Week 5, Week 11

• Maximal Dynamic Strength

  Maximal dynamic strength on the back squat exercise in kilograms lifted

  Baseline, Week 5, Week 11

• Surface EMG

  Using surface electromyography (EMG), the muscle activation of the plantarflexors muscles will me assessed, as well as the quadriceps femoris during the leg press and back squat exercise

  Baseline, Week 5, Week 11

• H-reflex excitability

  Using percutaneous electrostimulation of the tibial nerve, spinal reflex excitability will be explored by assessing H-reflex evoked responses

  Baseline, Week 5, Week 11

• V-wave

  Using percutaneous electrostimulation of the tibial nerve, neural drive to the active muscle will be assessed by measuring V-wave amplitudes

  Baseline, Week 5, Week 11

• Lower Body Muscle Power

  Lower body muscle power in watts will be assessed during countermovement jumps

  Baseline, Week 5, Week 11

• Muscle fascicle length

  Fascicle length of the vastus lateralis muscles in centimeters

  Baseline, Week 5, Week 11

• Muscle fascicle pennation angle

  Pennation angle of the vastus laterais fascicles, in degrees

  Baseline, Week 5, Week 11

• Muscle thickenss

  Muscle thickenss of the vastus lateralis, in centimeters

  Baseline, Week 5, Week 11

Study Arms (3)

Endurance

EXPERIMENTAL

Behavioral: Endurance Exercise

Strength

EXPERIMENTAL

Behavioral: Strength Exercise

Concurrent

EXPERIMENTAL

Behavioral: Concurrent Exercise

Interventions

Endurance Exercise BEHAVIORAL

30 minutes of running at an intensity corresponding to the heavy-domain (between the first and second ventilatory thresholds)

Endurance

Strength Exercise BEHAVIORAL

Combination of strength and power exercises Weeks 1-5 focus on building maximal strength Weeks 6-11 focus on maintaining maximal strength and improve muscle power

Strength

Concurrent Exercise BEHAVIORAL

Combining both strength and endurance training programs, with strength preceding endurance, incorporating a 20-min rest period between each modality

Concurrent

Eligibility Criteria

• Age: 18 Years - 30 Years
• Sex: male
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may not qualify if:

• Active smoking status
• Orthopedic injuries
• On medication
• Known cardiovascular or respiratory disease

Sponsors & Collaborators

• University of Lisbon: lead
• Fundação para a Ciência e a Tecnologia: collaborator

Study Sites (1)

Faculdade de Motricidade Humana - Universidade de Lisboa

Lisbon, Cruz Quebrada - Dafundo, 1499-002, Portugal

Location

MeSH Terms

Conditions

Motor Activity

Condition Hierarchy (Ancestors)

Behavior

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Invited Assistant Professor

Study Record Dates

• First Submitted: April 8, 2024
• First Posted: April 22, 2024
• Study Start: April 1, 2022
• Primary Completion: July 30, 2024
• Study Completion: July 30, 2025
• Last Updated: December 3, 2024

Record last verified: 2024-11

Data Sharing

• IPD Sharing: Will not share

Locations

PT (1)