Isolated or Combined Use of NUTRIC Score and NRS-2002 to Predict Mortality in the Intensive Care Unit

NCT06115525 | Completed

• 1 other identifier: 2012-KAEK-15/2627
• Study Type: observational
• Target: 750
• Locations: 1 country
• Sites: 1

Brief Summary

The objective of this investigation was to assess the predictive capacity of the NUTRIC Score and NRS-2002, separately or combined, in forecasting hospital, 28-day and 3-month mortality in patients with respiratory failure admitted to the intensive care unit.

Conditions

Nutrition Disorders; Malnutrition; Mortality

Keywords

mNUTRIC; NRS-2002; Respiratory Failure; Intensive Care Unit; Nutrition

Outcome Measures

Primary Outcomes (1)

• Mortality

  Mortality data of patients admitted to the intensive care unit due to respiratory failure during 3-month follow-up period

  3 month

Secondary Outcomes (2)

• mNUTRIC score

  72 hours

• NRS-2002 score

  72 hours

Study Arms (2)

Survivors

Patients admitted to the intensive care unit due to respiratory failure with no mortality in the 3-month follow-up period

Other: mNUTRIC score; Other: NRS-2002

Nonsurvivors

Patients who were admitted to the intensive care unit due to respiratory failure and mortality was observed in the 3-month follow-up period

Other: mNUTRIC score; Other: NRS-2002

Interventions

mNUTRIC score OTHER

The mNUTRIC score is a useful means of gauging the nutritional risk of patients in intensive care. Originally designed for IC unit patients, the score is calculated even when patient cooperation is unfeasible, making it applicable for intubated patients. Information necessary for calculation can be obtained from the patient's kin. The mNUTRIC score (without IL-6) classifies patients according to predefined metrics. The following information is necessary: (1) the patient's age, (2) their APACHE II score, (3) their SOFA score, (4) their comorbidities, and (5) the number of days they were hospitalized before being admitted to ICU.

Also known as: Modified Nutrition Risk in Critically Ill Score

Nonsurvivors; Survivors

NRS-2002 OTHER

The NRS-2002 score is a tool utilised to measure the nutritional risk of patients in intensive care units. This tool was specifically developed for the purpose of evaluating intensive care unit patients and can be calculated without requiring the patient's active involvement. Additionally, it can be applied to patients who have been intubated and the required information can be sourced from their family members or relatives. The Nutritional Risk Screening (NRS)-2002 assesses a patient's nutritional risk based on five variables: (1) recent unexplained weight loss, (2) appetite, (3) BMI, (4) disease-related stress factors (comorbidities), and (5) age over 70 years which is an additional risk factor.

Also known as: Nutritional Risk Score-2002

Nonsurvivors; Survivors

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

All adult patients (aged ≥18) admitted to the Intensive Care Units at the Anesthesiology and Reanimation Clinic of Ankara Atatürk Sanatorium Training and Research Hospital with respiratory distress, who remain in ICU for over 72 hours and meet the study criteria, are included.

You may qualify if:

• All patients aged 18 and over
• Admission to the intensive care unit due to respiratory failure (respiratory distress is included in the complaints of patients when admitted to the intensive care unit).

You may not qualify if:

• Patients diagnosed with neurodegenerative diseases (Alzheimer's disease and other dementia diseases, Parkinson's disease, Prion disease, Motor neuron diseases, Huntington's Disease, Spinocerebellar ataxia, Spinal muscular atrophy)
• Pregnant patients
• Patients with a length of stay in the ICU of less than 72 hours
• Patients in the terminal period who were diagnosed with malignancy and whose treatment process was terminated due to lack of response to treatment.

Sponsors & Collaborators

• Ankara Ataturk Sanatorium Training and Research Hospital: lead

Study Sites (1)

Ankara Atatürk Sanatorium Training and Research Hospital

Ankara, Keçiören, 06290, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Nutrition Disorders; Malnutrition; Respiratory Insufficiency

Condition Hierarchy (Ancestors)

Nutritional and Metabolic Diseases; Respiration Disorders; Respiratory Tract Diseases

Study Officials

• Onur KÜÇÜK, specialist

  Ankara Ataturk Sanatorium Training and Research Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER GOV
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Department of anesthesiology and reanimation, Principal Investigator, Specialist Doctor

Study Record Dates

• First Submitted: October 30, 2023
• First Posted: November 3, 2023
• Study Start: February 10, 2023
• Primary Completion: August 10, 2023
• Study Completion: November 10, 2023
• Last Updated: December 1, 2023

Record last verified: 2023-11

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)